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Hamster Monoclonal Cyclin B1 Primary Antibody für BI, FM - ABIN967426
Cao, Faha, Dembski, Tsai, Harlow, Dyson: Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F. in Nature 1992
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Human Polyclonal Cyclin B1 Primary Antibody für WB - ABIN3043482
Ren, Huang, Xu, Yang, Yang, Hu: Isoflavone lupiwighteone induces cytotoxic, apoptotic, and antiangiogenic activities in DU-145 prostate cancer cells. in Anti-cancer drugs 2015
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Human Polyclonal Cyclin B1 Primary Antibody für FACS, IF (cc) - ABIN670296
Ghate, Chaudhuri, Sarkar, Sajem, Panja, Rout, Mandal: An antioxidant extract of tropical lichen, Parmotrema reticulatum, induces cell cycle arrest and apoptosis in breast carcinoma cell line MCF-7. in PLoS ONE 2013
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Human Polyclonal Cyclin B1 Primary Antibody für DB, WB - ABIN1881155
Kreis, Sanhaji, Krämer, Sommer, Rödel, Strebhardt, Yuan: Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells. in Oncogene 2010
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Human Monoclonal Cyclin B1 Primary Antibody für ICC, FACS - ABIN969006
Chou, Yen, Lee, Chen: Pro-apoptotic role of Cdc25A: activation of cyclin B1/Cdc2 by the Cdc25A C-terminal domain. in The Journal of biological chemistry 2010
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Human Monoclonal Cyclin B1 Primary Antibody für IHC, ELISA - ABIN969005
Okayama, Kumamoto, Saitou, Hayase, Kofunato, Sato, Miyamoto, Nakamura, Ohki, Sekikawa, Takenoshita: CD44v6, MMP-7 and nuclear Cdx2 are significant biomarkers for prediction of lymph node metastasis in primary gastric cancer. in Oncology reports 2009
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Human Polyclonal Cyclin B1 Primary Antibody für PLA, WB - ABIN514100
Liu, Chen, Chau, Jan, Chen, Hsu, Lin, Juang, Lu, Cheng, Chen, Chang, Ting, Kao, Hsiao, Huang: Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma. in Molecular & cellular proteomics : MCP 2013
Human Polyclonal Cyclin B1 Primary Antibody für FACS, IF (cc) - ABIN670303
Dai, Ye, Peng, Zhou, Bai, Xiao, Ma, Zhou, Tang, Yao, Cao, Qin, Liu, Tan: Aptamer TY04 inhibits the growth of multiple myeloma cells via cell cycle arrest. in Tumour biology 2014
Human Polyclonal Cyclin B1 Primary Antibody für IF (p), IHC (p) - ABIN684448
Hawash, Kahraman, Eren, Cetin Atalay, Baytas: Synthesis and biological evaluation of novel pyrazolic chalcone derivatives as novel hepatocellular carcinoma therapeutics. in European journal of medicinal chemistry 2017
Human Monoclonal Cyclin B1 Primary Antibody für CyTOF, FACS - ABIN4265759
Valdez, Li, Murray, Ji, Liu, Popat, Champlin, Andersson: Comparison of the cytotoxicity of cladribine and clofarabine when combined with fludarabine and busulfan in AML cells: Enhancement of cytotoxicity with epigenetic modulators. in Experimental hematology 2015
intestinal clock controls the expression of key cell cycle regulators, such as cdc2 (zeige CDK1 Antikörper), wee1 (zeige WEE1 Antikörper), p21 (zeige CDKN1A Antikörper), PCNA (zeige PCNA Antikörper) and cdk2 (zeige CDK2 Antikörper), but only weakly influences cyclin B1, cyclin B2 (zeige CCNB2 Antikörper) and cyclin E1 (zeige CCNE1 Antikörper) expression.
the sequence in the coding region of cyclin B1 mRNA plays an important role as a cis (zeige CISH Antikörper)-acting element in both subcellular localization and translational timing of mRNA
Reporter mRNAs with the whole cyclin B1 sequence precisely mimic the localization & translation of endogenous cyclin B1 mRNA. mRNAs containing cyclin B1 3' UTR (zeige UTS2R Antikörper) but lacking ORFs had abnormal localization & precocious translational activation.
zebrafish cyclin B1 3'UTR (zeige UTS2R Antikörper) was quantitatively less effective at stimulating polyadenylation and translation compared to the Xenopus cyclin B1 3'UTR (zeige UTS2R Antikörper) during both zebrafish and Xenopus oocyte maturation
Data show that CDK1 (zeige CDK1 Antikörper) and cyclin B synergize during oocyte maturation to inhibit Myt1 (zeige PKMYT1 Antikörper) ensuring meiotic progression.
new role for Erk (zeige MAPK1 Antikörper) in mitotic regulation, identification of the Ser (zeige SIGLEC1 Antikörper) 101-directed kinase, and a picture of cyclin B1/Cdc2 regulation by the combinatorial action of distinct kinases
Cyclin B1 displays cytoskeleton-dependent localization in blastomere cortex during Xenopus embryonic cell cycle.
Cyclin B dissociation from CDK1 (zeige CDK1 Antikörper) precedes cyclins B degradation upon CDK1 (zeige CDK1 Antikörper) inactivation in mitotic embryo extracts and that proteasome proteolytic activity is dispensable for both activation and inactivation of CDK1 (zeige CDK1 Antikörper) in such extracts.
Defective cyclin B1 induction by T-DM1 (zeige DMPK Antikörper) mediates acquired resistance in HER2 (zeige ERBB2 Antikörper)-positive breast cancer cells.
Up-regulation of CCNB1 could be an indicator for invasiveness of pituitary adenomas.Up-regulation of CCNB1 could be an indicator for invasiveness of pituitary adenomas.
We identified the known APC (zeige APC Antikörper)/C regulator Cdh1 (zeige CDH1 Antikörper) and the F-box protein (zeige FBXW10 Antikörper) Fbxl15 (zeige FBXL15 Antikörper) as specific modulators of N-cyclin B1-luciferase steady-state levels and turnover. Collectively, our studies suggest that analyzing the steady-state levels of luciferase fusion proteins in parallel facilitates identification of specific regulators of protein turnover.
Overexpression of cyclin B1 is correlated with poor survival in most solid tumors, which suggests that the expression status of cyclin B1 is a significant prognostic parameter in solid tumors. [review]
CDK9 (zeige CDK9 Antikörper), in addition to CDK1 (zeige CDK1 Antikörper), has roles in mediating the growth inhibitory effect of dinaciclib on cyclin B1 in triple negative breast cancer
Data show that Islet-1 (ISL1 (zeige ISL1 Antikörper)) activated the expression of cyclin B1 (CCNB1), cyclin B2 (CCNB2 (zeige CCNB2 Antikörper)) and c-myc (c-MYC (zeige MYC Antikörper)) genes by binding to the conserved binding sites on their promoters or enhancers.
XIAP (zeige XIAP Antikörper) is stable during mitotic arrest, but its function is controlled through phosphorylation by the mitotic kinase CDK1 (zeige CDK1 Antikörper)-cyclin-B1 at S40.
ZIC5 (zeige ZIC5 Antikörper) is highly upregulated in non-small cell lung cancer tumor tissues and may act as an oncogene (zeige RAB1A Antikörper) by influencing CCNB1 and CDK1 (zeige CDK1 Antikörper) complex expression
Knockdown of DRG2 (zeige DRG2 Antikörper) elicited down-regulation of the major mitotic promoting factor, the cyclin B1/Cdk1 (zeige CDK1 Antikörper) complex.
Mitochondrial Ribosomal Protein L10 regulates cyclin B1/Cdk1 (cyclin-dependent kinase 1 (zeige CDK1 Antikörper)) activity and mitochondrial protein (zeige COX6B2 Antikörper) synthesis in mammalian cells
Results indicate that CCNB1 is critically required for the proliferation of gonocytes and spermatogonia but may be redundant in meiosis of spermatocytes in mouse spermatogenesis.
Results provide evidence that cdc2 (zeige CDK1 Antikörper)/cyclin B1 kinase activation was synchronous with the initial appearance of cytoskeletal lesions in mouse with Niemann-Pick disease type C.
Inhibition of CDK7 (zeige CDK7 Antikörper) bypasses spindle assembly checkpoint via premature cyclin B degradation during oocyte meiosis.
timing of Ccnb1 mRNA translation in mouse oocytes is dependent on the presence of transcripts with different 3' untranslated regions
AURKA (zeige AURKA Antikörper) induced phosphorylation and recruitment of CDC25B (zeige CDC25B Antikörper) to MTOCs prior to p-Cyclin B1-Ser123, and this sequential regulation is essential for the commitment of the oocytes to resume meiosis.
that MAD2B may play an important role in high glucose-mediated podocyte injury of diabetic nephropathy via modulation of Cdh1, cyclin B1, and Skp2 expression
Parvovirus-induced depletion of cyclin B1 prevents mitotic entry of infected cells.
Cyclin B1/Cdk1 (zeige CDK1 Antikörper)-mediated phosphorylation of mitochondrial substrates allows cells to sense and respond to increased energy demand for G2/M transition and, subsequently, to upregulate mitochondrial respiration for successful cell-cycle progression.
sticky siRNAs against survivin (zeige BIRC5 Antikörper) and cyclin B1 efficiently blocks growth of established subcutaneaous B16-F10 (zeige F10 Antikörper) tumors as well as formation and dissemination of melanoma lung metastases.
Inhibitions of Aurora B (zeige AURKC Antikörper) and Cyclin-dependent kinase 1 (zeige CDK1 Antikörper) activity in vertebrate cells also have opposite effects on the timing of abscission.
Cyclin B1 plays a significant role in promoting the maturation of large-follicle oocytes.
cyclin B1 distribution in porcine oocytes is affected by demecolcine-assisted enucleation
germinal vesicle is not required for the activation of M phase promoting factor during the first meiosis, but it is required for the second meiosis because of its promotion of CCNB1 accumulation
Results describe the expression of maternal cyclin B1 and Cdc2 (zeige CDK1 Antikörper) during in vitro maturation of porcine oocytes.
Cyclin-dependent kinase (zeige CDK1 Antikörper) inhibition did not affect the expression (mRNA and protein levels) and localization of maturation promoting factor(MPF (zeige MSLN Antikörper)) and MAPK (zeige MAPK1 Antikörper), and had nearly no effect on kinase activities during maturation.
link between cytoplasmic polyadenylation of cyclin B1 and translation/appearance of cyclin B1 protein before in vitro maturation of oocytes
Polyadenylation of cyclin B1 was also completely prevented when 3'-dA was added at 0 hr, and greatly reduced when added at 6 hr
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.
, cyclin B1
, cyclin B4
, G2/mitotic-specific cyclin B1
, cyclin B1, related sequence 1
, cyclin B1, related sequence 13
, cyclin B