anti-Zebrafisch (Danio rerio) COPS5 Antikörper für Western Blotting

Recommended COPS5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) Antikörper
  • BcDNA.LD14392
  • BcDNA:LD14392
  • CG14884
  • CH5
  • CSN-5
  • Csn5
  • DCH5
  • Dch5
  • Dmel\\CG14884
  • JAB1
  • JAB1/CSN5
  • Jab1
  • JadBp
  • csn5
  • dch5
  • jab1/csn5
  • l(3)89Cf
  • l(3)L4032
  • l(3)M203
  • quo
  • COPS5
  • MGC76063
  • AI303502
  • CSN5
  • Mov34
  • Sgn5
  • zgc:73130
  • MOV-34
  • SGN5
  • COP9 signalosome subunit 5
  • COP9 signalosome complex subunit 5
  • COP9 signalosome subunit 5 S homeolog
  • CSN5
  • COPS5
  • cops5
  • CpipJ_CPIJ012314
  • Bm1_46585
  • VDBG_06932
  • LOAG_01443
  • csn5
  • Cops5
  • cops5.S
  • csn-5
Epitop
N-Term
12
6
4
2
2
2
2
2
2
2
2
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
121
103
65
18
7
7
6
4
3
3
3
2
2
2
1
1
1
Wirt
Kaninchen
76
54
2
Klonalität
Polyklonal
Konjugat
Dieser COPS5 Antikörper ist unkonjugiert
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
114
62
43
39
33
22
19
14
1
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Produktnummer ABIN2777332
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
7.8026066 ABIN2706422 IHC WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
1 ABIN2619458 IHC IHC (p) WB Rabbit Internal Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN1977960 IF IHC IHC (p) WB Rabbit IgG AA 175-225 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1822333 IF IP WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN2991919 IHC WB Rabbit Anmelden zum Anzeigen Polyclonal 0

General

Antigen COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) Antikörper
Epitop N-Term
(12), (6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
(121), (103), (65), (18), (7), (7), (6), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1)
Wirt Kaninchen
(76), (54), (2)
Klonalität
Polyklonal
Konjugat Dieser COPS5 Antikörper ist unkonjugiert
(2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(114), (62), (43), (39), (33), (22), (19), (14), (1)
Pubmed 1 Publikation vorhanden
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Produktdetails anti-COPS5 Antikörper

Target Details COPS5 Anwendungsinformationen Handhabung Referenzen für anti-COPS5 Antikörper (ABIN2777332) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN975194.
Sequenz AASGSGMAQK TWELANNMQE AQSIDEIYKY DKKQQQEILA AKPWTKDHHY
Homologie Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
Produktmerkmale This is a rabbit polyclonal antibody against COPS5. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human COPS5
Plasmids, Primers & others

Target Details COPS5

Produktdetails anti-COPS5 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-COPS5 Antikörper (ABIN2777332) Bilder zurück nach oben
Antigen
Andere Bezeichnung COPS5 (COPS5 Antibody Abstract)
Hintergrund COPS5 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CSN5, JAB1, MGC3149, MOV-34, SGN5
Protein Interaction Partner: COPS6, UBC, CUL1, NEDD8, PTGS2, GPS1, LRP1, RANBP9, APP, SIAH1, BACE1, CTNNB1, COPS5, STAT3, CREB3, COPS4, SART3, COPS3, EPB41L1, CAST, KIF5B, PDLIM7, SMAD4, FBXO6, COPS2, TYK2, CDK2, CENPW, CENPT, FBXW4, MYEOV2, COPS8, CHUK, IKBKB, DTL, CD93, DDO, SMAD2,
Protein Size: 334
Molekulargewicht 37 kDa
Gen-ID 10987
NCBI Accession NM_006837, NP_006828
UniProt Q92905
Pathways Zellzyklus

Anwendungsinformationen

Produktdetails anti-COPS5 Antikörper Target Details COPS5 Handhabung Referenzen für anti-COPS5 Antikörper (ABIN2777332) Bilder zurück nach oben
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 334 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-COPS5 Antikörper Target Details COPS5 Anwendungsinformationen Referenzen für anti-COPS5 Antikörper (ABIN2777332) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-COPS5 Antikörper (ABIN2777332)

Produktdetails anti-COPS5 Antikörper Target Details COPS5 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Zhang, Chen, Su, Yang, Lee: "Roles for CSN5 in control of p53/MDM2 activities." in: Journal of cellular biochemistry, Vol. 103, Issue 4, pp. 1219-30, 2008

Bilder

Produktdetails anti-COPS5 Antikörper Target Details COPS5 Anwendungsinformationen Handhabung Referenzen für anti-COPS5 Antikörper (ABIN2777332) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (N-Term) antibody (ABIN2777332) Sample Type: 1. Human blood cells, pure
2. Human blood cells, partially pur...
Western Blotting (WB) image for anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (N-Term) antibody (ABIN2777332) WB Suggested Anti-COPS5 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:2500 Posit...