anti-Human WNT5A Antikörper für Immunofluorescence

Recommended WNT5A Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) Antikörper
  • hWNT5A
  • wnt-5A
  • wnt5a-B
  • WNT5A
  • 8030457G12Rik
  • Wnt-5a
  • Wnt family member 5A
  • Wnt family member 5A S homeolog
  • wingless-type MMTV integration site family, member 5a
  • wingless-type MMTV integration site family, member 5A
  • wingless-related MMTV integration site 5A
  • Wnt signaling ligand
  • WNT5A
  • Wnt5a
  • wnt5a.S
  • wnt5a
  • LOC578814
  • wnt5
Reaktivität
Human
173
66
51
19
17
16
2
2
1
1
1
1
1
Wirt
Maus
133
52
2
Klonalität
Monoklonal
Konjugat
Dieser WNT5A Antikörper ist unkonjugiert
11
10
8
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
149
71
58
57
16
13
10
10
6
4
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN967259
$ 528.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
14.30825 ABIN1109513 EIA IF IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 6F2 1
13 ABIN462542 ELISA IF IHC IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 6F2 0
12.755764 ABIN4902466 ELISA IF IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 6F2 0
12.755764 ABIN5622869 ELISA IF IHC WB Mouse IgG1 Anmelden zum Anzeigen 6F2 0
10 ABIN5590970 ELISA IF IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 6F2 0
4 ABIN2470810 IF IHC ELISA WB Mouse IgG1 Anmelden zum Anzeigen 6F2 0
1 ABIN2769264 ELISA IF IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 6F2 0
1 ABIN2387316 IF IHC ELISA WB Mouse IgG1 Anmelden zum Anzeigen 6F2 0
1 ABIN1580251 IF IHC ELISA WB Mouse Anmelden zum Anzeigen 0

General

Antigen Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) Antikörper
Reaktivität Human
(173), (66), (51), (19), (17), (16), (2), (2), (1), (1), (1), (1), (1)
Wirt Maus
(133), (52), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser WNT5A Antikörper ist unkonjugiert
(11), (10), (8), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(149), (71), (58), (57), (16), (13), (10), (10), (6), (4), (1), (1), (1)
Pubmed 3 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-WNT5A Antikörper

Target Details WNT5A Anwendungsinformationen Handhabung Referenzen für anti-WNT5A Antikörper (ABIN967259) Bilder
Reinigung Ascitic fluid
Immunogen Purified recombinant fragment of human XBP1 expressed in E. Coli.
Klon 6F2
Isotyp IgG1
Plasmids, Primers & others

Target Details WNT5A

Produktdetails anti-WNT5A Antikörper Anwendungsinformationen Handhabung Referenzen für anti-WNT5A Antikörper (ABIN967259) Bilder zurück nach oben
Antigen
Andere Bezeichnung WNT5A (WNT5A Antibody Abstract)
Hintergrund This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5.
Synonyms: hWNT5A
Molekulargewicht 42.3kDa
Gen-ID 7474
Pathways WNT Signalweg, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size, Tube Formation

Anwendungsinformationen

Produktdetails anti-WNT5A Antikörper Target Details WNT5A Handhabung Referenzen für anti-WNT5A Antikörper (ABIN967259) Bilder zurück nach oben
Applikations-hinweise Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-WNT5A Antikörper Target Details WNT5A Anwendungsinformationen Referenzen für anti-WNT5A Antikörper (ABIN967259) Bilder zurück nach oben
Format Liquid
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C

Referenzen für anti-WNT5A Antikörper (ABIN967259)

Produktdetails anti-WNT5A Antikörper Target Details WNT5A Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Martino, Olsen, Fulcher, Wolfgang, ONeal, Ribeiro: "Airway epithelial inflammation-induced endoplasmic reticulum Ca2+ store expansion is mediated by X-box binding protein-1." in: The Journal of biological chemistry, Vol. 284, Issue 22, pp. 14904-13, 2009

Schardt, Weber, Eyholzer, Mueller, Pabst: "Activation of the unfolded protein response is associated with favorable prognosis in acute myeloid leukemia." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 11, pp. 3834-41, 2009

Allgemeine Veröffentlichungen

Jiang, Yang, Thorne, Zhu, Hersey, Zhang: "Human melanoma cells under endoplasmic reticulum stress acquire resistance to microtubule-targeting drugs through XBP-1-mediated activation of Akt." in: Neoplasia (New York, N.Y.), Vol. 11, Issue 5, pp. 436-47, 2009