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anti-Human DKK1 Antikörper:
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Human Monoclonal DKK1 Primary Antibody für IHC (p), IP - ABIN524880
DAmelio, Roato, DAmico, Veneziano, Suman, Sassi, Bisignano, Ferracini, Gargiulo, Castoldi, Pescarmona, Isaia: Bone and bone marrow pro-osteoclastogenic cytokines are up-regulated in osteoporosis fragility fractures. in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2011
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Human Monoclonal DKK1 Primary Antibody für ELISA, WB - ABIN966001
Bond, Kuhn, Binstadt, Quirk, Wu, Tews, Dev, Ericsson: The use of simulation in the development of individual cognitive expertise in emergency medicine. in Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2008
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Dog (Canine) Polyclonal DKK1 Primary Antibody für IF (p), IHC (p) - ABIN678158
Król, Mucha, Majchrzak, Homa, Bulkowska, Majewska, Gajewska, Pietrzak, Perszko, Romanowska, Paw?owski, Manuali, Hellmen, Motyl: Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors. in PLoS ONE 2014
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Human Monoclonal DKK1 Primary Antibody für ELISA, WB - ABIN969085
Yamamoto, Sakane, Yamamoto, Michiue, Kikuchi: Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling. in Developmental cell 2008
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Human DKK1 Primary Antibody für IHC (p) - ABIN643515
de Andrade, de Castro, Vicente, da Rosa, Nader, Pereira, Fröde: Evaluation of circulating levels of inflammatory and bone formation markers in axial spondyloarthritis. in International immunopharmacology 2014
Human Polyclonal DKK1 Primary Antibody für IHC (p), ELISA - ABIN250268
Fedi, Bafico, Nieto Soria, Burgess, Miki, Bottaro, Kraus, Aaronson: Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling. in The Journal of biological chemistry 1999
Human Monoclonal DKK1 Primary Antibody für IHC (p), IP - ABIN524877
Brunetti, Faienza, Piacente, Ventura, Oranger, Carbone, Benedetto, Colaianni, Gigante, Mori, Gesualdo, Colucci, Cavallo, Grano: High dickkopf-1 levels in sera and leukocytes from children with 21-hydroxylase deficiency on chronic glucocorticoid treatment. in American journal of physiology. Endocrinology and metabolism 2013
Human Polyclonal DKK1 Primary Antibody für IHC (p), WB - ABIN388360
Yan, Wu, Chen, Diao, Lai, Huang, Chen, Yu, Gui, Tang, Cai: Developmental expression and function of DKKL1/Dkkl1 in humans and mice. in Reproductive biology and endocrinology : RB&E 2012
Human Polyclonal DKK1 Primary Antibody für IHC (p), ELISA - ABIN4369827
Krupnik, Sharp, Jiang, Robison, Chickering, Amaravadi, Brown, Guyot, Mays, Leiby, Chang, Duong, Goodearl, Gearing, Sokol, McCarthy: Functional and structural diversity of the human Dickkopf gene family. in Gene 1999
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Sclerostin (zeige SOST Antikörper) But Not Dickkopf-1 has roles in increasing prevalence of osteoporotic fracture and lower bone mineral density in postmenopausal Korean women
High serum levels of sclerostin (zeige SOST Antikörper) and Dkk-1 are associated with acute ischaemic stroke
regulated by Dkk-1 secreted by Multiple Myeloma cells and is a potential mechanism contributing to the osteoblast dysfunction noted in Multiple Myeloma.
DKK1 c.121G>A (p.(A41T)) variant was identified in the family with Chiari malformation type 1. Screening of DKK1 in a cohort of 65 CMI sporadic patients identified another missense variant, the c.359G>T (p.(R120L)), in two unrelated patients.
LRP6 (zeige LRP6 Antikörper) ectodomain becomes highly compact upon complexation with the Wnt (zeige WNT2 Antikörper) antagonist Dkk1, suggesting a potential role for the ectodomain conformational change in the regulation of receptor oligomerization and signaling.
Our results suggest that measurement of DKK-1 combined with DKK-1 autoantibodies is a potentially valuable tool for the early detection of ESCC.
TET1 (zeige TET1 Antikörper) potently inhibited canonical Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling by demethylating and upregulating two upstream antagonists of this pathway, SFRP2 (zeige SFRP2 Antikörper) and DKK1, which was associated with inhibition of EMT (zeige ITK Antikörper) and cancer cell metastasis.
This is the first study demonstrating a link between B cell depletion and skin Dkk-1 upregulation in patients with systemic sclerosis
We found significantly increased levels of DKK-1 in patients with acute CO poisoning, compared to healthy controls. High levels of serum DKK-1 in patients were significantly correlated with severe neurological symptoms.
DKK1 prevents lung metastasis of breast cancer cells but promotes breast-to-bone metastasis.
The decreased expression of Dkk-1 in somatic cell nuclear transfer cotyledons that are prone to abnormal placentation suggests a role in cotyledon formation but the mechanism and regulatory control is yet to be revealed[DICKKOPF-1]
Palmatin effect on osteoarthritis is likely mediated via the Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) and Hedgehog (zeige SHH Antikörper) signaling
DKK1 inhibits the WNT (zeige WNT2 Antikörper) signaling pathway and improves pig oocyte maturation.
Association analysis showed that different genotypes of DKK1 were associated with loin muscle area.
activation of the FGF signaling pathway induces the formation of a dorsal axis with a complete head structure through the expression of chd (zeige CHRD Antikörper) and subsequent maintenance of dkk1b expression levels.
Kremen1 (zeige KREMEN1 Antikörper) modulates Wnt (zeige WNT2 Antikörper) activity by restricting the range of secreted Dkk proteins during collective cell migration in the posterior lateral line primordium
Neuromast size is controlled by a balance between growth-promoting Wnt (zeige WNT2 Antikörper) signaling activity in proliferation-competent cells and Wnt (zeige WNT2 Antikörper)-inhibiting Dkk activity produced by differentiated sensory cells.
Dkk1b is abundantly produced by dense regions of androgen-regulated epidermal tubercles on the surfaces of adult male zebrafish pectoral fins
Data show that injury-dependent induction of Ascl1a (zeige ASCL1A Antikörper) suppressed expression of the Wnt (zeige WNT2 Antikörper) signaling inhibitor, Dkk, and induced expression of the Wnt (zeige WNT2 Antikörper) ligand, Wnt4a.
Membrane-bound DKK-1 is a novel Foxp3 (zeige FOXP3 Antikörper) postive Treg cell derived mediator to maintain immunological tolerance in T-cell-mediated autoimmune colitis.
Dkk1 promotes hematopoietic regeneration via direct effects on hematopoietic stem cells, decreasing the levels of mitochondrial reactive oxygen species and suppressing senescence, and via indirect effects on bone marrow endothelial cells, inducing EGF (zeige EGF Antikörper) secretion.
Recombinant Dkk1 suppresses beta-catenin (zeige CTNNB1 Antikörper) target genes in myeloid-derived suppressor cells (MDSCs) from mice and humans and anti-Dkk1 loses its antitumor effects in mice lacking beta-catenin (zeige CTNNB1 Antikörper) in myeloid cells or after depletion of MDSCs, demonstrating that Dkk1 directly targets MDSCs.
A negative feedback loop involving WNT6 (zeige WNT6 Antikörper) and DKK1 attenuates canonical WNT6 (zeige WNT6 Antikörper)-beta-catenin (zeige CTNNB1 Antikörper) signaling, thereby allowing teratocarcinoma cells to differentiate.
Collectively, miR (zeige MLXIP Antikörper)-9 promotes osteoblast differentiation of mesenchymal stem cells by suppressing DKK1 gene expression.
that Dkk1 negatively regulates BMP9 (zeige GDF2 Antikörper)-induced osteogenic differentiation.
Disturbed oscillatory flow increases DKK1 expression. DKK1 knockdown attenuates OSS-induced monocyte adhesion and endothelial impairment. Genetic silencing of DKK1 limits atherogenesis in ApoE (zeige APOE Antikörper)-/- mice.
Dickkopf1 receptor Kremen1 (zeige KREMEN1 Antikörper) is a bona fide dependence receptor, triggering cell death unless bound to its ligand.
These results suggest that inhibiting Wnt (zeige WNT2 Antikörper) signaling in embryonic stem cells using DKK1 may promote mouse ESCs (zeige NR2E3 Antikörper) to differentiate into endoderm in vitro and in vivo
dkk1 preferentially induced the expression of POX2, suggesting that dkk1 works as a morphogen (zeige SHH Antikörper) to determine the different lineages.
N1 is a novel signaling domain within the intact protein that is responsible for the potent effects of Dkk1 on the induction and patterning of the body axis and heart
target Wnts of Dkk activity are maternal Wnt5a (zeige WNT5A Antikörper) and Wnt11, and that both Wnts are essential for canonical and non-canonical signaling
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
dickkopf 1 homolog
, dickkopf related protein-1
, dickkopf-1 like
, dickkopf-like protein 1
, dickkopf-related protein 1
, dickkopf homolog 1
, dickkopf 1
, dickkopf protein