anti-Human WNT5A Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended WNT5A Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) Antikörper
  • hWNT5A
  • wnt-5A
  • wnt5a-B
  • WNT5A
  • 8030457G12Rik
  • Wnt-5a
  • Wnt family member 5A
  • Wnt family member 5A S homeolog
  • wingless-type MMTV integration site family, member 5a
  • wingless-type MMTV integration site family, member 5A
  • wingless-related MMTV integration site 5A
  • Wnt signaling ligand
  • WNT5A
  • Wnt5a
  • wnt5a.S
  • wnt5a
  • LOC578814
  • wnt5
Epitop
AA 330-380
36
15
14
11
11
7
7
6
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Hund, Human, Maus, Ratte (Rattus)
177
65
50
19
16
16
2
2
1
1
1
1
1
Wirt
Kaninchen
133
56
2
Klonalität
Polyklonal
Konjugat
Dieser WNT5A Antikörper ist unkonjugiert
11
10
8
5
5
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
150
75
61
58
17
12
10
10
6
4
1
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN675758
$ 318.45
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
10.876529 ABIN449945 ICC IF IHC (p) IHC ELISA WB Mouse IgG1 Anmelden zum Anzeigen 6F2 0
1 ABIN651869 FACS IHC (p) WB Rabbit Ig Fraction AA 185-213, Center Anmelden zum Anzeigen Polyclonal 4
1 ABIN3043962 IHC (p) WB Rabbit IgG AA 184-303 Anmelden zum Anzeigen Polyclonal 0
1 ABIN207746 IHC IHC (p) WB Rabbit IgG AA 190-230 Anmelden zum Anzeigen Polyclonal 0
1 ABIN574490 IHC IHC (p) WB Rabbit IgG AA 180-229 Anmelden zum Anzeigen Polyclonal 0
1 ABIN4366183 ELISA IHC IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 3D10 1
1 ABIN4366188 IHC IHC (p) WB Rabbit Anmelden zum Anzeigen Polyclonal 9
1 ABIN462542 ELISA IF IHC IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 6F2 0
1 ABIN462561 ELISA IHC IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 3D10 0
1 ABIN599464 ELISA IHC IHC (p) Mouse IgG2a, kappa AA 201-301 Anmelden zum Anzeigen 3A4 0
1 ABIN5534831 FACS IHC (p) WB Rabbit Ig Fraction AA 185-213 Anmelden zum Anzeigen Polyclonal 0
1 ABIN4902466 ELISA IF IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 6F2 0
1 ABIN4902467 ELISA IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 3D10 0
1 ABIN4366186 IHC IHC (p) WB Rabbit IgG Center Anmelden zum Anzeigen Polyclonal 0
1 ABIN675760 IHC (p) WB Biotin Rabbit IgG AA 330-380 Anmelden zum Anzeigen Polyclonal 1
1 ABIN675767 IHC (p) WB HRP Rabbit IgG AA 330-380 Anmelden zum Anzeigen Polyclonal 0
1 ABIN521385 IHC (p) ELISA Mouse IgG2a kappa AA 201-300, partial Anmelden zum Anzeigen 3A4 1
1 ABIN959990 IHC IHC (p) Mouse IgG2a, kappa Anmelden zum Anzeigen IMG4M5E4 0
1 ABIN5590969 ELISA IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 3D10 0
1 ABIN5590970 ELISA IF IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 6F2 0

General

Antigen Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) Antikörper
Epitop AA 330-380
(36), (15), (14), (11), (11), (7), (7), (6), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Hund, Human, Maus, Ratte (Rattus)
(177), (65), (50), (19), (16), (16), (2), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(133), (56), (2)
Klonalität
Polyklonal
Konjugat Dieser WNT5A Antikörper ist unkonjugiert
(11), (10), (8), (5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(150), (75), (61), (58), (17), (12), (10), (10), (6), (4), (1), (1), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-WNT5A Antikörper

Target Details WNT5A Anwendungsinformationen Handhabung Referenzen für anti-WNT5A Antikörper (ABIN675758) Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human WNT5A
Isotyp IgG
Plasmids, Primers & others

Target Details WNT5A

Produktdetails anti-WNT5A Antikörper Anwendungsinformationen Handhabung Referenzen für anti-WNT5A Antikörper (ABIN675758) Bilder zurück nach oben
Antigen
Andere Bezeichnung Wnt5a (WNT5A Antibody Abstract)
Hintergrund

Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation. Stimulates cell migration. Decreases proliferation, migration, invasiveness and clonogenicity of carcinoma cells and may act as a tumor suppressor. Mediates motility of melanoma cells. Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle. Inhibits type II collagen expression in chondrocytes.

Subcellular location: Secreted

Synonyms: hWNT5A, Protein Wnt-5a, WNT5A

Gen-ID 7474
UniProt P41221
Pathways WNT Signalweg, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size, Tube Formation

Anwendungsinformationen

Produktdetails anti-WNT5A Antikörper Target Details WNT5A Handhabung Referenzen für anti-WNT5A Antikörper (ABIN675758) Bilder zurück nach oben
Applikations-hinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-WNT5A Antikörper Target Details WNT5A Anwendungsinformationen Referenzen für anti-WNT5A Antikörper (ABIN675758) Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Referenzen für anti-WNT5A Antikörper (ABIN675758)

Produktdetails anti-WNT5A Antikörper Target Details WNT5A Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Saha, Aranda, Hayakawa, Bhanja, Atay, Brodin, Li, Asfaha, Liu, Tailor, Zhang, Godwin, Tome, Wang, Guha, Pollard: "Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury." in: Nature communications, Vol. 7, pp. 13096, 2016

Król, Mucha, Majchrzak, Homa, Bulkowska, Majewska, Gajewska, Pietrzak, Perszko, Romanowska, Paw?owski, Manuali, Hellmen, Motyl: "Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors." in: PLoS ONE, Vol. 9, Issue 1, pp. e83995, 2014 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Dog (Canine)).

Bilder

Produktdetails anti-WNT5A Antikörper Target Details WNT5A Anwendungsinformationen Handhabung Referenzen für anti-WNT5A Antikörper (ABIN675758) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 330-380) antibody (ABIN675758) Frozen mouse brain sections labeled with Anti-WNT5A Polyclonal Antibody, Unconjugated...
Immunohistochemistry (IHC) image for anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 330-380) antibody (ABIN675758) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-WNT5A Pol...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 330-380) antibody (ABIN675758) Image kindly submitted by Dr. Magdalena Krol. Formalin-fixed and paraffin embedded ca...
Western Blotting (WB) image for anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 330-380) antibody (ABIN675758) Image kindly provided by Dr. Magdalena Krol. Control tumor cells, tumor cells grown i...
Western Blotting (WB) image for anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 330-380) antibody (ABIN675758) Mouse ovary lysates probed with WNT5A Polyclonal Antibody, unconjugated at 1:300 ove...
Western Blotting (WB) image for anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 330-380) antibody (ABIN675758) Mouse uterus lysates probed with WNT5A Polyclonal Antibody, unconjugated at 1:300 ov...