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Human FAM65B Protein expressed in Wheat germ - ABIN1353580
Rougerie, Largeteau, Megrelis, Carrette, Lejeune, Toffali, Rossi, Zeghouf, Cherfils, Constantin, Laudanna, Bismuth, Mangeney, Delon: Fam65b is a new transcriptional target of FOXO1 that regulates RhoA signaling for T lymphocyte migration. in Journal of immunology (Baltimore, Md. : 1950) 2013
FAM65B has a role in controlling proliferation of transformed and primary T cells
Mouse Ripor2 forms ring-like structures at the base of stereocilia and interacts with RhoC
In our analyses of the DYX2 locus, we observed associations of KIAA0319, ACOT13, and FAM65B with developing cortical thickness and/or functional anisotropy.
These data together elucidate a mechanism for RHOA and pMLC polarization in stimulated neutrophils through direct inhibition of RHOA by FAM65B at the leading edge.
Fam65b expression is necessary for the complex to form.
show that wild-type Fam65b is expressed during embryonic and postnatal development stages in murine cochlea, and that the protein localizes to the plasma membranes of the stereocilia of inner and outer hair cells of the inner ear
PC3 tumors are sustained by a small number of tumor-initiating cells with stem-like characteristics, including strong self-renewal and pro-angiogenic capability and marked by the expression pattern FAM65Bhigh/MFI2low/LEF1low.
C6ORF32 is a novel protein likely to play multiple functions, including promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation
RhoC co-localizes with Fam65b in stereocilia and regulates Fam65b oligomerization what is critical for hair cell function.
The protein encoded by this gene stimulates the formation of a non-mitotic multinucleate syncytium from proliferative cytotrophoblasts during trophoblast differentiation. Two alternatively spliced transcript variants have been found for this gene.
family with sequence similarity 65, member B
, myogenesis-related and NCAM-associated protein homolog
, protein FAM65B
, likely orthologue of H. sapiens chromosome 6 open reading frame 32 (C6orf32)
, myogenesis-related and NCAM-associated protein