Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Produkte
(Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
Kategorien
This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found. [provided by RefSeq, Jul 2008].
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Ausgewählte Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Kategorien
Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Antikörper
High quality antibodies with extensive validation data.
Tumor Necrosis Factor (Ligand) Superfamily, Member 11 ELISA Kits
Reliable ELISA kits for a wide range of species.
Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rabbit, Rat
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (12)
- (6)
Kat. Nr.
ABIN668556
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Monkey
Applikation
WB, ELISA, IHC, FACS, ICC
Validierungen
- (1)
- (8)
Kat. Nr.
ABIN5611143
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC (p), IF
Validierungen
- (6)
Kat. Nr.
ABIN7210648
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Tumor Necrosis Factor (Ligand) Superfamily, Member 11 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (11)
- (5)
Kat. Nr.
ABIN6574228
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (9)
- (1)
Kat. Nr.
ABIN6960248
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN6960249
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275517
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275516
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275518
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Produkten
: "Bone Remodeling in Mandible of Wistar Rats with Diabetes Mellitus and Osteoporosis." in: European journal of dentistry, (2022) (PubMed).: "Differential Expression of Dickkopf 1 and Periostin in Mouse Strains with High and Low Bone Mass." in: Biology, Vol. 11, Issue 12, (2022) (PubMed).
: "Comparison of RANKL expression, inflammatory markers, and cardiovascular risk in patients with acute coronary syndrome with and without rheumatoid arthritis." in: Rheumatology international, Vol. 39, Issue 10, pp. 1723-1732, (2020) (PubMed).
: "Mice lacking plastin-3 display a specific defect of cortical bone acquisition." in: Bone, Vol. 130, pp. 115062, (2020) (PubMed).
: "RANKL-mediated osteoclastogenic differentiation of macrophages in the abdominal aorta of angiotensin II-infused apolipoprotein E knockout mice." in: Journal of vascular surgery, Vol. 68, Issue 6S, pp. 48S-59S.e1, (2019) (PubMed).
: "The impact of forced swimming on expression of RANKL and OPG in a type 2 diabetes mellitus rat model." in: Archives of physiology and biochemistry, Vol. 125, Issue 3, pp. 195-200, (2019) (PubMed).
: "Role of interleukin-33 in the clinical pathogenesis of chronic apical periodontitis." in: The Journal of international medical research, Vol. 47, Issue 7, pp. 3332-3343, (2019) (PubMed).
: "Effects of the Highly COX-2-Selective Analgesic NSAID Etoricoxib on Human Periodontal Ligament Fibroblasts during Compressive Orthodontic Mechanical Strain." in: Mediators of inflammation, Vol. 2019, pp. 2514956, (2019) (PubMed).
: "The role of mechanotransduction versus hypoxia during simulated orthodontic compressive strain-an in vitro study of human periodontal ligament fibroblasts." in: International journal of oral science, Vol. 11, Issue 4, pp. 33, (2019) (PubMed).
: "The Role of MicroRNA-143-5p in the Differentiation of Dental Pulp Stem Cells into Odontoblasts by Targeting Runx2 via the OPG/RANKL Signaling Pathway." in: Journal of cellular biochemistry, Vol. 119, Issue 1, pp. 536-546, (2018) (PubMed).
Synonyme und alternative Namen zu Tumor Necrosis Factor (Ligand) Superfamily, Member 11
TNF superfamily member 11 (TNFSF11), tumor necrosis factor (ligand) superfamily, member 11 (Tnfsf11), TNF superfamily member 11 (Tnfsf11), TNF receptor superfamily member 11b (TNFRSF11B), TNF superfamily member 11 L homeolog (tnfsf11.L), CD254, cd254, hRANKL2, Ly109l, ODF, odf, OPG, OPGL, opgl, OPTB2, optb2, RANKL, rankl, sOdf, sodf, TNFSF11, tnfsf11, TRANCE, Trance, tranceBezeichner auf Proteinebene für Tumor Necrosis Factor (Ligand) Superfamily, Member 11
- TNF-related activation-induced cytokine
- osteoclast differentiation factor
- osteoprotegerin ligand
- receptor activator of nuclear factor kappa B ligand
- receptor activator of nuclear factor kappa-B ligand
- tumor necrosis factor ligand superfamily member 11
- tumor necrosis factor (ligand) superfamily, member 11
- Receptor activator of nuclear factor kappa-B ligand
- OPG ligand
- receptor activator of NF-kappaB ligand
- tumor necrosis factor-related activation-induced cytokine
- ODF
- OPGL
- TRANCE
- osteoprotegerin
- TNF superfamily member 11 L homeolog
- tumor necrosis factor superfamily member 11 L homeolog
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