anti-Ratte (Rattus) TNFAIP3 Antikörper für Immunohistochemistry

Recommended TNFAIP3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) Antikörper
  • tnfaip3
  • MGC82339
  • TNFAIP3
  • A20
  • OTUD7C
  • TNFA1P2
  • Tnfip3
  • TNF alpha induced protein 3
  • TNF alpha induced protein 3 S homeolog
  • tumor necrosis factor, alpha-induced protein 3
  • TNFAIP3
  • tnfaip3.S
  • Tnfaip3
Reaktivität
Maus, Ratte (Rattus), Human
103
67
64
6
2
1
1
Wirt
Kaninchen
72
25
6
Klonalität
Polyklonal
Konjugat
Dieser TNFAIP3 Antikörper ist unkonjugiert
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
74
38
36
31
28
27
19
13
10
6
3
2
2
2
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN3022985
$ 393.25
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
16.014114 ABIN6265632 ELISA ICC IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
10.014114 ABIN604690 ELISA IHC IHC (p) WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
10.014114 ABIN1031138 IHC ELISA WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 0
10.014114 ABIN1030759 IHC ELISA WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
10 ABIN1875125 ICC IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
4 ABIN478080 IHC ELISA WB Rabbit IgG Internal Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN2880119 ICC IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN2574921 ICC IF IHC IHC (p) WB Rabbit Internal Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN2894550 IHC WB Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN1887667 IHC ELISA WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
1 ABIN1886989 IHC ELISA WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN2902986 ELISA IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN1994956 IHC WB Rabbit IgG Anmelden zum Anzeigen 0

General

Antigen Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) Antikörper
Reaktivität Maus, Ratte (Rattus), Human
(103), (67), (64), (6), (2), (1), (1)
Wirt Kaninchen
(72), (25), (6)
Klonalität
Polyklonal
Konjugat Dieser TNFAIP3 Antikörper ist unkonjugiert
(4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(74), (38), (36), (31), (28), (27), (19), (13), (10), (6), (3), (2), (2), (2)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TNFAIP3 Antikörper

Target Details TNFAIP3 Anwendungsinformationen Handhabung Bilder
Reinigung Affinity purification
Immunogen Recombinant protein of human TNFAIP3
Isotyp IgG
Plasmids, Primers & others

Target Details TNFAIP3

Produktdetails anti-TNFAIP3 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung TNFAIP3 (TNFAIP3 Antibody Abstract)
Hintergrund A20, also referred to as TNF-alpha-induced protein 3 (TNFAIP3), is cytokine-inducible protein that functions to inhibit apoptosis and activate NF-kappaB. It was first identified as a TNF-alpha inducible primary response gene in human umbilical vein endothelial cells, and encodes a 790 AA protein containing seven Cys2/Cys2-zinc finger motifs. Constitutive expression of A20 is observed in lymphoid tissues , but it is transiently expressed in a variety of cell types in response to inflammatory signals such as TNF-alpha , IL-1 , phorbol esters , and LPS. Expression of A20 can confer resistance to apoptosis and NF-kappaB activation triggered by these signals, probably through interference with TRAF (TNF receptor associated factor) family members , and interaction with the NF-kappaB inhibiting protein ABIN. Studies also show that A20 contains site-specific ubiquitin modifying activity that can contribute to its biological functions. The amino-terminus of A20 contains de-ubiquitinating (DUB) activity for Lys63 branches, such as those found in TRAF6 and RIP, while the carboxyl-terminus contains ubiquitin ligase (E3) activity for Lys48 branches of the same substrates and leads to their degradation.
Synonyms: A20, MGC104522, MGC138687, MGC138688, OTUD7C, TNFA1P2
Gen-ID 7128
UniProt P21580
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Production of Molecular Mediator of Immune Response

Anwendungsinformationen

Produktdetails anti-TNFAIP3 Antikörper Target Details TNFAIP3 Handhabung Bilder zurück nach oben
Applikations-hinweise Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TNFAIP3 Antikörper Target Details TNFAIP3 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze / thaw cycles
Lagerung -20 °C/-80 °C

Bilder

Produktdetails anti-TNFAIP3 Antikörper Target Details TNFAIP3 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunofluorescence (IF) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibody (ABIN3022985) Immunofluorescence analysis of U2OS cell using TNFAIP3 antibody. Blue: DAPI for nucle...
Western Blotting (WB) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibody (ABIN3022985) Western blot analysis of extracts of various cell lines, using TNFAIP3 antibody.