anti-Maus TNFAIP3 Antikörper für ELISA

Recommended TNFAIP3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) Antikörper
  • tnfaip3
  • MGC82339
  • TNFAIP3
  • A20
  • OTUD7C
  • TNFA1P2
  • Tnfip3
  • TNF alpha induced protein 3
  • TNF alpha induced protein 3 S homeolog
  • tumor necrosis factor, alpha-induced protein 3
  • TNFAIP3
  • tnfaip3.S
  • Tnfaip3
Reaktivität
Human, Maus, Ratte (Rattus)
103
67
64
6
2
1
1
Wirt
Kaninchen
72
25
6
Klonalität
Polyklonal
Konjugat
Dieser TNFAIP3 Antikörper ist unkonjugiert
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
74
38
35
30
28
26
19
13
10
6
3
2
2
2
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN6265632
$ 390.77
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
7 ABIN2889421 IF ELISA WB Rabbit IgG AA 321-370 Anmelden zum Anzeigen Polyclonal 0
7 ABIN604690 ELISA IHC IHC (p) WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
7 ABIN1031138 IHC ELISA WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 0
7 ABIN1030759 IHC ELISA WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
4 ABIN1740182 IHC (p) ELISA WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
4 ABIN478080 IHC ELISA WB Rabbit IgG Internal Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN2747660 ELISA WB FITC Rabbit IgG AA 690-790 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2747659 ELISA WB Rabbit IgG AA 690-790 Anmelden zum Anzeigen Polyclonal 0
1 ABIN5878733 ELISA IF/ICC WB Rabbit IgG Internal Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN6101772 ELISA IF/ICC WB Rabbit IgG Internal Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN5698569 ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN1887667 IHC ELISA WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
1 ABIN1886989 IHC ELISA WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN2902986 ELISA IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN5878730 ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN5557989 ELISA WB Biotin Rabbit Anmelden zum Anzeigen Polyclonal 0

General

Antigen Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(103), (67), (64), (6), (2), (1), (1)
Wirt Kaninchen
(72), (25), (6)
Klonalität
Polyklonal
Konjugat Dieser TNFAIP3 Antikörper ist unkonjugiert
(4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(74), (38), (35), (30), (28), (26), (19), (13), (10), (6), (3), (2), (2), (2)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TNFAIP3 Antikörper

Target Details TNFAIP3 Anwendungsinformationen Handhabung Bilder
Spezifität TNFAIP3 Antibody detects endogenous levels of total TNFAIP3
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Immunogen A synthesized peptide derived from human TNFAIP3
Isotyp IgG
Plasmids, Primers & others

Target Details TNFAIP3

Produktdetails anti-TNFAIP3 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung TNFAIP3 (TNFAIP3 Antibody Abstract)
Hintergrund

Description: Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity. Essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. In cooperation with TAX1BP1 promotes disassembly of E2-E3 ubiquitin protein ligase complexes in IL-1R and TNFR-1 pathways, affected are at least E3 ligases TRAF6, TRAF2 and BIRC2, and E2 ubiquitin-conjugating enzymes UBE2N and UBE2D3. In cooperation with TAX1BP1 promotes ubiquitination of UBE2N and proteasomal degradation of UBE2N and UBE2D3. Upon TNF stimulation, deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Deubiquitinates TRAF6 probably acting on 'Lys-63'-linked polyubiquitin. Upon T-cell receptor (TCR)-mediated T-cell activation, deubiquitinates 'Lys-63'-polyubiquitin chains on MALT1 thereby mediating disassociation of the CBM (CARD11:BCL10:MALT1) and IKK complexes and preventing sustained IKK activation. Deubiquitinates NEMO/IKBKG, the function is facilitated by TNIP1 and leads to inhibition of NF-kappa-B activation. Upon stimulation by bacterial peptidoglycans, probably deubiquitinates RIPK2. Can also inhibit I-kappa-B-kinase (IKK) through a non-catalytic mechanism which involves polyubiquitin, polyubiquitin promotes association with IKBKG and prevents IKK MAP3K7-mediated phosphorylation. Targets TRAF2 for lysosomal degradation. In vitro able to deubiquitinate 'Lys-11'-, 'Lys-48'- and 'Lys-63' polyubiquitin chains. Inhibitor of programmed cell death. Has a role in the function of the lymphoid system. Required for LPS-induced production of proinflammatory cytokines and IFN beta in LPS-tolerized macrophages.

Gene: TNFAIP3

Molekulargewicht 90kDa
Gen-ID 7128
UniProt P21580
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Production of Molecular Mediator of Immune Response

Anwendungsinformationen

Produktdetails anti-TNFAIP3 Antikörper Target Details TNFAIP3 Handhabung Bilder zurück nach oben
Applikations-hinweise WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TNFAIP3 Antikörper Target Details TNFAIP3 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months

Bilder

Produktdetails anti-TNFAIP3 Antikörper Target Details TNFAIP3 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibody (ABIN6265632) Western blot analysis of Hepg2 whole cell lysates, using TNFAIP3 Antibody. The lane ...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibody (ABIN6265632) ABIN6277109 staining RAW264.7 cells by IF/ICC. The sample were fixed with PFA and pe...
Immunohistochemistry (IHC) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibody (ABIN6265632) ABIN6277109 at 1/100 staining Rat kidney tissue by IHC-P. The sample was formaldehyde...
Western Blotting (WB) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibody (ABIN6265632) Western blot analysis of extracts from various samples, using TNFAIP3 Antibody. Lane...