anti-Human TNFAIP3 Antikörper für Western Blotting

Recommended TNFAIP3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) Antikörper
  • tnfaip3
  • MGC82339
  • TNFAIP3
  • A20
  • OTUD7C
  • TNFA1P2
  • Tnfip3
  • TNF alpha induced protein 3
  • TNF alpha induced protein 3 S homeolog
  • tumor necrosis factor, alpha-induced protein 3
  • TNFAIP3
  • tnfaip3.S
  • Tnfaip3
Epitop
C-Term
34
15
5
4
3
2
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
103
67
64
6
2
1
1
Wirt
Maus
73
24
6
Klonalität
Monoklonal
Konjugat
Dieser TNFAIP3 Antikörper ist unkonjugiert
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Simple Western (SimWes), Western Blotting (WB)
74
37
35
31
30
26
18
13
9
6
3
2
1
1
Hersteller
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Bilder

Produktnummer ABIN4277015
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.0788064 ABIN2788768 WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
3.0788064 ABIN5947830 FACS ICC IF IHC IHC (p) WB Rabbit IgG AA 500-600 Anmelden zum Anzeigen SN07-31 0
3.0788064 ABIN1875125 ICC IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
3.0788064 ABIN615697 EIA IHC (p) WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
3.0788064 ABIN4277012 ELISA ICC IF IHC IHC (p) WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
3.0788064 ABIN4277013 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
3.0788064 ABIN2973497 WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
3.0788064 ABIN3022985 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
3.0788064 ABIN1030759 IHC ELISA WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
3.0788064 ABIN1031138 IHC ELISA WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 0
3.0788064 ABIN4277017 WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
3.0788064 ABIN5589783 ELISA IHC WB Rabbit Anmelden zum Anzeigen Polyclonal 0
3.0788064 ABIN5589782 ELISA IHC WB Rabbit Anmelden zum Anzeigen Polyclonal 0
3.0788064 ABIN5014473 ICC IHC WB Rabbit IgG AA 1-300 Anmelden zum Anzeigen Polyclonal 0
3.0788064 ABIN2904365 IF/ICC IHC IP WB Rabbit AA 1-300 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2889421 IF ELISA WB Rabbit IgG AA 321-370 Anmelden zum Anzeigen Polyclonal 0
1 ABIN680938 IF (p) IHC (p) WB Rabbit IgG AA 80-103 Anmelden zum Anzeigen Polyclonal 0
1 ABIN604690 ELISA IHC IHC (p) WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN207992 IP WB Mouse IgG Anmelden zum Anzeigen 59A426  0
1 ABIN1740182 IHC (p) ELISA WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0

General

Antigen Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) Antikörper
Epitop C-Term
(34), (15), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(103), (67), (64), (6), (2), (1), (1)
Wirt Maus
(73), (24), (6)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser TNFAIP3 Antikörper ist unkonjugiert
(4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Simple Western (SimWes), Western Blotting (WB)
(74), (37), (35), (31), (30), (26), (18), (13), (9), (6), (3), (2), (1), (1)
Pubmed 38 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TNFAIP3 Antikörper

Target Details TNFAIP3 Anwendungsinformationen Handhabung Referenzen für anti-TNFAIP3 Antikörper (ABIN4277015) Bilder
Reinigung Protein G purified
Immunogen Full length recombinant human A20. The epitope has been mapped to the C-terminal portion of A20 (amino acids 440-790)
Klon 59A426
Isotyp IgG1 kappa
Plasmids, Primers & others

Target Details TNFAIP3

Produktdetails anti-TNFAIP3 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TNFAIP3 Antikörper (ABIN4277015) Bilder zurück nach oben
Antigen
Andere Bezeichnung A20/TNFAIP3 (TNFAIP3 Antibody Abstract)
Hintergrund Gene Symbol: TNFAIP3
Gen-ID 7128
UniProt P21580
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Production of Molecular Mediator of Immune Response

Anwendungsinformationen

Produktdetails anti-TNFAIP3 Antikörper Target Details TNFAIP3 Handhabung Referenzen für anti-TNFAIP3 Antikörper (ABIN4277015) Bilder zurück nach oben
Applikations-hinweise Western Blot 2-4 μg/mL, Simple Western 1:100, Flow Cytometry 1:20-1:2000, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunoprecipitation 1-2 μg/mL, Immunohistochemistry-Paraffin 1:10-1:500, CyTOF-readyThe A20 antibody (clone 59A426) has also been used in Immunohistochemistry-Paraffin (Metellus, 2010) and Flow Cytometry (intracellular) (Hjelmeland, 2010). Multiple A20 cleavage fragments have been described in Western Blot, see Coornaert (2008) and Hailfinger (2009) for additional details. In Simple Western only 10 - 15 μL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TNFAIP3 Antikörper Target Details TNFAIP3 Anwendungsinformationen Referenzen für anti-TNFAIP3 Antikörper (ABIN4277015) Bilder zurück nach oben
Format Liquid
Konzentration 1.0 mg/mL
Buffer PBS
Buffer contains: 0.05 % Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze-thaw cycles.

Referenzen für anti-TNFAIP3 Antikörper (ABIN4277015)

Produktdetails anti-TNFAIP3 Antikörper Target Details TNFAIP3 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Lim, Maubach, Sokolova, Feige, Diezko, Buchbinder, Backert, Schlüter, Lavrik, Naumann: "Pathogen-induced ubiquitin-editing enzyme A20 bifunctionally shuts off NF-κB and caspase-8-dependent apoptotic cell death." in: Cell death and differentiation, Vol. 24, Issue 9, pp. 1621-1631, 2017 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human).

Reihill, Malcomson, Bertelsen, Cheung, Czerwiec, Barsden, Elborn, Dürkop, Hirsch, Ennis, Kelly, Schock: "Induction of the inflammatory regulator A20 by gibberellic acid in airway epithelial cells." in: British journal of pharmacology, Vol. 173, Issue 4, pp. 778-89, 2016 (Probematerial (Species): Human). Weitere Details: Western Blotting

Perez, Jukica, Listopad, Anders, Kühl, Loddenkemper, Blankenstein, Charo: "Permissive expansion and homing of adoptively transferred T cells in tumor-bearing hosts." in: International journal of cancer, Vol. 137, Issue 2, pp. 359-71, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

De, Dainichi, Rathinam, Ghosh: "The deubiquitinase activity of A20 is dispensable for NF-κB signaling." in: EMBO reports, Vol. 15, Issue 7, pp. 775-83, 2014 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Lai, Wu, Tsai, Chuang, Chuang, Hsu, Lai: "Transcription of Tnfaip3 is regulated by NF-κB and p38 via C/EBPβ in activated macrophages." in: PLoS ONE, Vol. 8, Issue 9, pp. e73153, 2013 (Probematerial (Species): Mouse (Murine)).

Svingerud, Solstad, Sun, Nyrud, Kileng, Greiner-Tollersrud, Robertsen: "Atlantic salmon type I IFN subtypes show differences in antiviral activity and cell-dependent expression: evidence for high IFNb/IFNc-producing cells in fish lymphoid tissues." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 12, pp. 5912-23, 2012

Frenzel, Claus, Plume, Schwamb, Konermann, Pallasch, Claasen, Brinker, Wollnik, Plass, Wendtner: "Sustained NF-kappaB activity in chronic lymphocytic leukemia is independent of genetic and epigenetic alterations in the TNFAIP3 (A20) locus." in: International journal of cancer, Vol. 128, Issue 10, pp. 2495-500, 2011

Imbeault, Ouellet, Giguère, Bertin, Bélanger, Martin, Tremblay: "Acquisition of host-derived CD40L by HIV-1 in vivo and its functional consequences in the B-cell compartment." in: Journal of virology, Vol. 85, Issue 5, pp. 2189-200, 2011

Adrianto, Wen, Templeton, Wiley, King, Lessard, Bates, Hu, Kelly, Kaufman, Guthridge, Alarcón-Riquelme, Anaya, Bae, Bang, Boackle, Brown, Petri, Gallant, Ramsey-Goldman, Reveille, Vila, Criswell et al.: "Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus. ..." in: Nature genetics, Vol. 43, Issue 3, pp. 253-8, 2011

Hövelmeyer, Reissig, Xuan, Adams-Quack, Lukas, Nikolaev, Schlüter, Waisman: "A20 deficiency in B cells enhances B-cell proliferation and results in the development of autoantibodies." in: European journal of immunology, Vol. 41, Issue 3, pp. 595-601, 2011

Gerlach, Cordier, Schmukle, Emmerich, Rieser, Haas, Webb, Rickard, Anderton, Wong, Nachbur, Gangoda, Warnken, Purcell, Silke, Walczak: "Linear ubiquitination prevents inflammation and regulates immune signalling." in: Nature, Vol. 471, Issue 7340, pp. 591-6, 2011

Karube, Nakagawa, Tsuzuki, Takeuchi, Honma, Nakashima, Shimizu, Ko, Morishima, Ohshima, Nakamura, Seto: "Identification of FOXO3 and PRDM1 as tumor-suppressor gene candidates in NK-cell neoplasms by genomic and functional analyses." in: Blood, Vol. 118, Issue 12, pp. 3195-204, 2011

Hjelmeland, Wu, Wickman, Eyler, Heddleston, Shi, Lathia, Macswords, Lee, McLendon, Rich: "Targeting A20 decreases glioma stem cell survival and tumor growth." in: PLoS biology, Vol. 8, Issue 2, pp. e1000319, 2010

Harada, Kanehira, Fujisawa, Takata, Shuin, Miki, Fujioka, Nakamura, Katagiri: "Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells." in: Cancer research, Vol. 70, Issue 14, pp. 5829-39, 2010

Malinverni, Unterreiner, Staal, Demeyer, Galaup, Luyten, Beyaert, Bornancin: "Cleavage by MALT1 induces cytosolic release of A20." in: Biochemical and biophysical research communications, Vol. 400, Issue 4, pp. 543-7, 2010

Li, Soetandyo, Wang, Ye: "The zinc finger protein A20 targets TRAF2 to the lysosomes for degradation." in: Biochimica et biophysica acta, Vol. 1793, Issue 2, pp. 346-53, 2009

Breckpot, Aerts-Toegaert, Heirman, Peeters, Beyaert, Aerts, Thielemans: "Attenuated expression of A20 markedly increases the efficacy of double-stranded RNA-activated dendritic cells as an anti-cancer vaccine." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 2, pp. 860-70, 2009

Verhelst, Verstrepen, Coornaert, Carpentier, Beyaert: "Cellular expression of A20 and ABIN-3 in response to Toll-like receptor-4 stimulation." in: Methods in molecular biology (Clifton, N.J.), Vol. 517, pp. 205-15, 2009

Schmitz, Hansmann, Bohle, Martin-Subero, Hartmann, Mechtersheimer, Klapper, Vater, Giefing, Gesk, Stanelle, Siebert, Küppers: "TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma." in: The Journal of experimental medicine, Vol. 206, Issue 5, pp. 981-9, 2009

Düwel, Welteke, Oeckinghaus, Baens, Kloo, Ferch, Darnay, Ruland, Marynen, Krappmann: "A20 negatively regulates T cell receptor signaling to NF-kappaB by cleaving Malt1 ubiquitin chains." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 12, pp. 7718-28, 2009

Bilder

Produktdetails anti-TNFAIP3 Antikörper Target Details TNFAIP3 Anwendungsinformationen Handhabung Referenzen für anti-TNFAIP3 Antikörper (ABIN4277015) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (C-Term) antibody (ABIN4277015) Flow Cytometry: A20/TNFAIP3 Antibody (59A426) [NBP1-77533] - Intracellular flow cytom...
Simple Western (SimWes) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (C-Term) antibody (ABIN4277015) Simple Western: A20/TNFAIP3 Antibody (59A426) [NBP1-77533] - Simple Western lane view...
Flow Cytometry (FACS) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (C-Term) antibody (ABIN4277015) Flow Cytometry: A20/TNFAIP3 Antibody (59A426) [NBP1-77533] - Analysis of PE conjugate...
Western Blotting (WB) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (C-Term) antibody (ABIN4277015) Western Blot: A20/TNFAIP3 Antibody (59A426) [NBP1-77533] - Analysis of A20 using mAb ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (C-Term) antibody (ABIN4277015) Immunohistochemistry-Paraffin: A20/TNFAIP3 Antibody (59A426) [NBP1-77533] - Formalin-...
Western Blotting (WB) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (C-Term) antibody (ABIN4277015) Western Blot: A20/TNFAIP3 Antibody (59A426) [NBP1-77533] - Human Jurkat lysate probed...
Flow Cytometry (FACS) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (C-Term) antibody (ABIN4277015) Flow Cytometry: A20/TNFAIP3 Antibody (59A426) - An intracellular stain was performed...
Flow Cytometry (FACS) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (C-Term) antibody (ABIN4277015) Flow Cytometry: A20/TNFAIP3 Antibody (59A426) - An intracellular stain was performed...