anti-Human TLR8 Antikörper für Enzyme Immunoassay

Recommended TLR8 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 8 (TLR8) Antikörper
  • CD288
  • toll like receptor 8
  • toll-like receptor 8
  • TLR8
  • Tlr8
Epitop
Internal Region
42
21
20
15
10
8
7
7
7
5
4
4
3
2
2
2
1
1
1
1
1
Reaktivität
Human, Maus
240
119
47
2
2
2
2
2
2
1
1
1
1
Wirt
Kaninchen
177
79
10
2
Klonalität
Polyklonal
Konjugat
Dieser TLR8 Antikörper ist unkonjugiert
19
18
15
10
8
8
7
7
4
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
168
114
81
72
47
16
15
13
8
5
4
3
3
3
2
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN303155
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN5555341 EIA IF WB Rabbit IgG Middle Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN5556602 EIA IHC (p) Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN5556603 EIA IHC (p) Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0

General

Antigen Toll-Like Receptor 8 (TLR8) Antikörper
Epitop Internal Region
(42), (21), (20), (15), (10), (8), (7), (7), (7), (5), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Reaktivität Human, Maus
(240), (119), (47), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(177), (79), (10), (2)
Klonalität
Polyklonal
Konjugat Dieser TLR8 Antikörper ist unkonjugiert
(19), (18), (15), (10), (8), (8), (7), (7), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(168), (114), (81), (72), (47), (16), (15), (13), (8), (5), (4), (3), (3), (3), (2)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR8 Antikörper

Target Details TLR8 Anwendungsinformationen Handhabung Bilder
Kreuzreaktivität (Details) Species reactivity (expected):Mouse.
Species reactivity (tested):Human.
Reinigung Immunoaffinity Chromatography.
Immunogen Synthetic peptide corresponding to an internal region of human TLR8 protein - KLH conjugated
Plasmids, Primers & others

Target Details TLR8

Produktdetails anti-TLR8 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung CD288 / TLR8 (TLR8 Antibody Abstract)
Hintergrund Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.Synonyms: Toll-like receptor 8, UNQ249/PRO286
Gen-ID 51311
NCBI Accession NP_619542
UniProt Q9NR97
Pathways TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR8 Antikörper Target Details TLR8 Handhabung Bilder zurück nach oben
Applikations-hinweise Western Blot: 1/500-1/2000. ELISA: 1/2000-1/10000. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR8 Antikörper Target Details TLR8 Anwendungsinformationen Bilder zurück nach oben
Konzentration 1.0 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Bilder

Produktdetails anti-TLR8 Antikörper Target Details TLR8 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
 image for anti-Toll-Like Receptor 8 (TLR8) (Internal Region) antibody (ABIN303155) anti-Toll-Like Receptor 8 (TLR8) (Internal Region) antibody