anti-Ratte (Rattus) TLR7 Antikörper für Immunohistochemistry

Recommended TLR7 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 7 (TLR7) Antikörper
  • TLR7-like
  • RGD1563357
  • toll like receptor 7
  • toll-like receptor 7
  • TLR7
  • Tlr7
Reaktivität
Maus, Ratte (Rattus), Human
267
140
43
4
4
3
2
2
2
2
1
1
1
1
1
Wirt
Kaninchen
201
85
2
1
Klonalität
Polyklonal
Konjugat
Dieser TLR7 Antikörper ist unkonjugiert
19
15
12
11
8
6
5
4
4
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
207
104
93
74
48
47
40
16
13
6
5
5
4
2
Optionen
Hersteller
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Bilder

Produktnummer ABIN3021247
$ 393.25
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
15.863952 ABIN1875113 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
9.863952 ABIN6265603 ELISA IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
9.863952 ABIN2421031 IHC ELISA Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
9.863952 ABIN2427617 IHC ELISA Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN2629317 IHC IHC (p) WB Rabbit IgG AA 1020-1038 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2893974 IHC WB Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN5701344 ELISA IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN6672341 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN2902850 ELISA IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN5905724 IHC WB Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN1994953 IHC WB Rabbit IgG Anmelden zum Anzeigen 0
1 ABIN5905725 ELISA IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0

General

Antigen Toll-Like Receptor 7 (TLR7) Antikörper
Reaktivität Maus, Ratte (Rattus), Human
(267), (140), (43), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(201), (85), (2), (1)
Klonalität
Polyklonal
Konjugat Dieser TLR7 Antikörper ist unkonjugiert
(19), (15), (12), (11), (8), (6), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(207), (104), (93), (74), (48), (47), (40), (16), (13), (6), (5), (5), (4), (2)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR7 Antikörper

Target Details TLR7 Anwendungsinformationen Handhabung Bilder
Reinigung Affinity purification
Immunogen Recombinant protein of human TLR7
Isotyp IgG
Plasmids, Primers & others

Target Details TLR7

Produktdetails anti-TLR7 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung TLR7 (TLR7 Antibody Abstract)
Hintergrund Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-kappaB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 AAs known as the TIR domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor), MAL/TIRAP (MyD88-adaptor-like/TIR-associated protein), TRIF (Toll-receptor-associated activator of interferon), and TRAM (Toll-receptor-associated molecule). This association leads to the recruitment and activation of IRAK1 and IRAK4, which form a complex with TRAF6 to activate TAK1 and IKK. Activation of IKK leads to the degradation of IkappaB that normally maintains NF-kappaB inactivity by sequestering it in the cytoplasm. TLR7, 8 and 9 form a group of structurally related TLR family members that are are localized to intracellular endosomes. TLR7 shows highest expression in lung, placenta, and spleen. TLR7 mediates responses to a class of synthetic compounds, including imidazoquinolines, guanosine-based drugs that induce anti-viral responses. Naturally, TLR7 responds to ssRNA viruses to activate NF-kappaB and trigger IFN production.
Synonyms: TLR7
Gen-ID 51284
UniProt Q9NYK1
Pathways TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR7 Antikörper Target Details TLR7 Handhabung Bilder zurück nach oben
Applikations-hinweise Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR7 Antikörper Target Details TLR7 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze / thaw cycles
Lagerung -20 °C/-80 °C

Bilder

Produktdetails anti-TLR7 Antikörper Target Details TLR7 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Toll-Like Receptor 7 (TLR7) antibody (ABIN3021247) Western blot analysis of Ramos cell lysate using TLR7 antibody.
Immunofluorescence (IF) image for anti-Toll-Like Receptor 7 (TLR7) antibody (ABIN3021247) Immunofluorescence analysis of MCF7 cell using TLR7 antibody. Blue: DAPI for nuclear ...