anti-Human TLR7 Antikörper für Immunohistochemistry

Recommended TLR7 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 7 (TLR7) Antikörper
  • TLR7-like
  • RGD1563357
  • toll like receptor 7
  • toll-like receptor 7
  • TLR7
  • Tlr7
Reaktivität
Maus, Ratte (Rattus), Human
261
138
42
4
4
3
2
2
2
2
1
1
1
1
1
Wirt
Kaninchen
196
83
2
1
Klonalität
Polyklonal
Konjugat
Dieser TLR7 Antikörper ist unkonjugiert
19
15
12
11
8
6
5
4
4
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
200
101
90
72
48
47
38
15
13
6
5
5
4
2
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN3021247
$ 393.25
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
12.992776 ABIN604913 FACS IHC IHC (p) WB Rabbit IgG AA 900-950 Anmelden zum Anzeigen Polyclonal 0
12.992776 ABIN2998417 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
12.755764 ABIN5564262 FACS IHC WB Mouse IgG1 AA 500-900 Anmelden zum Anzeigen ABM2C27 0
12.755764 ABIN571500 FACS IHC WB Rabbit Extracellular Domain Anmelden zum Anzeigen Polyclonal 0
12.755764 ABIN571503 FACS IHC WB Goat Extracellular Domain Anmelden zum Anzeigen Polyclonal 0
10 ABIN2988976 IF/ICC IHC Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
9.992776 ABIN334260 FACS IHC IHC (fro) IHC (p) WB Rabbit IgG AA 706-728 Anmelden zum Anzeigen Polyclonal 0
9.992776 ABIN6265603 ELISA IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
9.992776 ABIN214002 ICC IHC IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
9.992776 ABIN2470507 FACS IHC WB Rabbit IgG AA 706-728 Anmelden zum Anzeigen Polyclonal 0
9.992776 ABIN5965993 IF IHC Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
9.992776 ABIN3029179 IHC ELISA WB Rabbit Ig Fraction AA 98-128 Anmelden zum Anzeigen Polyclonal 0
9.992776 ABIN2427617 IHC ELISA Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
9.992776 ABIN2421031 IHC ELISA Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
7 ABIN1875113 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
7 ABIN1860776 ICC IHC WB Rabbit IgG AA 887-1036 Anmelden zum Anzeigen Polyclonal 0
7 ABIN2903147 IF/ICC IHC IP WB Rabbit AA 887-1036 Anmelden zum Anzeigen Polyclonal 0
4 ABIN208869 FACS IHC IHC (fro) Rabbit IgG AA 650-700 Anmelden zum Anzeigen Polyclonal 0
4 ABIN200019 FACS IHC IHC (fro) IHC (p) WB Rabbit AA 706-728 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2629317 IHC IHC (p) WB Rabbit IgG AA 1020-1038 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Toll-Like Receptor 7 (TLR7) Antikörper
Reaktivität Maus, Ratte (Rattus), Human
(261), (138), (42), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(196), (83), (2), (1)
Klonalität
Polyklonal
Konjugat Dieser TLR7 Antikörper ist unkonjugiert
(19), (15), (12), (11), (8), (6), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(200), (101), (90), (72), (48), (47), (38), (15), (13), (6), (5), (5), (4), (2)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR7 Antikörper

Target Details TLR7 Anwendungsinformationen Handhabung Bilder
Reinigung Affinity purification
Immunogen Recombinant protein of human TLR7
Isotyp IgG
Plasmids, Primers & others

Target Details TLR7

Produktdetails anti-TLR7 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung TLR7 (TLR7 Antibody Abstract)
Hintergrund Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-kappaB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 AAs known as the TIR domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor), MAL/TIRAP (MyD88-adaptor-like/TIR-associated protein), TRIF (Toll-receptor-associated activator of interferon), and TRAM (Toll-receptor-associated molecule). This association leads to the recruitment and activation of IRAK1 and IRAK4, which form a complex with TRAF6 to activate TAK1 and IKK. Activation of IKK leads to the degradation of IkappaB that normally maintains NF-kappaB inactivity by sequestering it in the cytoplasm. TLR7, 8 and 9 form a group of structurally related TLR family members that are are localized to intracellular endosomes. TLR7 shows highest expression in lung, placenta, and spleen. TLR7 mediates responses to a class of synthetic compounds, including imidazoquinolines, guanosine-based drugs that induce anti-viral responses. Naturally, TLR7 responds to ssRNA viruses to activate NF-kappaB and trigger IFN production.
Synonyms: TLR7
Gen-ID 51284
UniProt Q9NYK1
Pathways TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR7 Antikörper Target Details TLR7 Handhabung Bilder zurück nach oben
Applikations-hinweise Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR7 Antikörper Target Details TLR7 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze / thaw cycles
Lagerung -20 °C/-80 °C

Bilder

Produktdetails anti-TLR7 Antikörper Target Details TLR7 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Toll-Like Receptor 7 (TLR7) antibody (ABIN3021247) Western blot analysis of Ramos cell lysate using TLR7 antibody.
Immunofluorescence (IF) image for anti-Toll-Like Receptor 7 (TLR7) antibody (ABIN3021247) Immunofluorescence analysis of MCF7 cell using TLR7 antibody. Blue: DAPI for nuclear ...