General
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Antigen
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Toll-Like Receptor 7 (TLR7) Antikörper
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Epitop
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AA 900-950
Alternativen
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Reaktivität
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Rind (Kuh), Hund, Pferd, Human, Affe, Maus, Ratte (Rattus)
Alternativen
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Wirt
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Kaninchen
Alternativen
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Klonalität
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Konjugat
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Dieser TLR7 Antikörper ist unkonjugiert
Alternativen
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Applikation
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternativen
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Hersteller
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Anmelden zum Anzeigen
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Spezifität
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This antibody reacts to Toll-like Receptor 7 (TLR7).
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Reinigung
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Protein G Chromatography
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Immunogen
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Synthetic peptide - KLH conjugated, A portion of amino acids 900-950 of human TLR7 Genename: TLR7
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Isotyp
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IgG
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Plasmids, Primers & others
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Antigen
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Andere Bezeichnung
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TLR7 (TLR7 Antibody Abstract)
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Hintergrund
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Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus. Activation of TLR7 by VSV results in stimulation of the immune response including IFNa secretion, suggesting the importance of TLR7 in virus recognition.Synonyms: Toll-like receptor 7
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Gen-ID
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51284
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NCBI Accession
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NP_057646
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UniProt
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Q9NYK1
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Pathways
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TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades
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Applikations-hinweise
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Optimal working dilution should be determined by the investigator.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Konzentration
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0,5 mg/mL
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Buffer
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PBS containing 0.2 % gelatin and 0.05 % sodium azide as preservative
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Konservierungs-mittel
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Sodium azide
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Vorsichtsmaßnahmen
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This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
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Avoid repeated freezing and thawing.
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Lagerung
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4 °C/-20 °C
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Informationen zur Lagerung
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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Bilder des Herstellers
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