anti-Human TLR6 Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended TLR6 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 6 (TLR6) Antikörper
  • TLR1
  • TLR16
  • CD286
  • TLR-6
  • toll-like receptor 1 family member A
  • toll like receptor 6
  • toll-like receptor 6
  • TLR1A
  • TLR6
  • Tlr6
Epitop
AA 340-380
24
19
11
11
9
9
7
7
7
6
5
5
5
4
3
3
3
3
2
2
2
1
Reaktivität
Human, Maus, Ratte (Rattus)
194
68
9
3
3
2
1
1
Wirt
Kaninchen
135
73
14
Klonalität
Polyklonal
Konjugat
Dieser TLR6 Antikörper ist unkonjugiert
17
17
13
7
7
5
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
121
100
86
81
53
22
16
16
6
5
4
2
2
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN749573
$ 329.45
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
23.497421 ABIN252495 FACS IHC (p) IHC Mouse IgG1 Anmelden zum Anzeigen 86B1153-2 16
17.5 ABIN544511 IHC (p) ELISA WB Rabbit Anmelden zum Anzeigen Polyclonal 2
14.7556715 ABIN214529 ELISA IHC IHC (p) WB Rabbit IgG Internal Region Anmelden zum Anzeigen Polyclonal 0
14.5 ABIN388338 FACS IHC (p) WB Rabbit Ig Fraction AA 393-423, C-Term Anmelden zum Anzeigen Polyclonal 1
11.7556715 ABIN214000 ICC IHC IHC (p) WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 0
11.5 ABIN531987 FACS IHC (p) Mouse IgG1 Anmelden zum Anzeigen 86B1153-2 1
10 ABIN357053 EIA IHC (p) WB Rabbit Ig Fraction C-Term Anmelden zum Anzeigen Polyclonal 2
10 ABIN357055 EIA IHC (p) Rabbit Ig Fraction C-Term Anmelden zum Anzeigen Polyclonal 2
10 ABIN388340 IHC (p) WB Rabbit Ig Fraction AA 722-753, C-Term Anmelden zum Anzeigen Polyclonal 0
10 ABIN5535024 IHC (p) WB Rabbit Ig Fraction AA 722-753, C-Term Anmelden zum Anzeigen Polyclonal 0
7 ABIN357054 EIA IHC (p) WB Rabbit Ig Fraction N-Term Anmelden zum Anzeigen Polyclonal 2
7 ABIN1539419 IHC (p) WB Rabbit Ig AA 1-30, N-Term Anmelden zum Anzeigen Polyclonal 0
7 ABIN1740122 IHC (p) WB Rabbit IgG Internal Region Anmelden zum Anzeigen Polyclonal 0
7 ABIN2682652 IHC (p) Rabbit IgG Center Anmelden zum Anzeigen Polyclonal 0
7 ABIN303301 IHC (p) WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
4 ABIN957517 IHC IHC (p) Rabbit AA 25-39 Anmelden zum Anzeigen Polyclonal 0
4 ABIN1740121 ICC IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
4 ABIN302880 IF IHC (p) WB Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN5555339 EIA IHC (p) WB Rabbit IgG Center Anmelden zum Anzeigen Polyclonal 0
1 ABIN1724250 FACS IHC (p) FITC Mouse IgG1 AA 408-424 Anmelden zum Anzeigen 86B1153-2 0

General

Antigen Toll-Like Receptor 6 (TLR6) Antikörper
Epitop AA 340-380
(24), (19), (11), (11), (9), (9), (7), (7), (7), (6), (5), (5), (5), (4), (3), (3), (3), (3), (2), (2), (2), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(194), (68), (9), (3), (3), (2), (1), (1)
Wirt Kaninchen
(135), (73), (14)
Klonalität
Polyklonal
Konjugat Dieser TLR6 Antikörper ist unkonjugiert
(17), (17), (13), (7), (7), (5), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(121), (100), (86), (81), (53), (22), (16), (16), (6), (5), (4), (2), (2), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR6 Antikörper

Target Details TLR6 Anwendungsinformationen Handhabung Referenzen für anti-TLR6 Antikörper (ABIN749573) Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human TLR6
Isotyp IgG
Plasmids, Primers & others

Target Details TLR6

Produktdetails anti-TLR6 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TLR6 Antikörper (ABIN749573) Bilder zurück nach oben
Antigen
Andere Bezeichnung Tlr6 (TLR6 Antibody Abstract)
Hintergrund

Participates in the innate immune response to Gram-positive bacteria and fungi. Specifically recognizes diacylated and, to a lesser extent, triacylated lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. In complex with TLR4, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalized and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.

Subcellular location: Extracellular

Synonyms: CD286, Toll-like receptor 6, TLR6

Gen-ID 10333
UniProt Q9Y2C9
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR6 Antikörper Target Details TLR6 Handhabung Referenzen für anti-TLR6 Antikörper (ABIN749573) Bilder zurück nach oben
Applikations-hinweise WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR6 Antikörper Target Details TLR6 Anwendungsinformationen Referenzen für anti-TLR6 Antikörper (ABIN749573) Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Referenzen für anti-TLR6 Antikörper (ABIN749573)

Produktdetails anti-TLR6 Antikörper Target Details TLR6 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Shmuel-Galia, Aychek, Fink, Porat, Zarmi, Bernshtein, Brenner, Jung, Shai: "Neutralization of pro-inflammatory monocytes by targeting TLR2 dimerization ameliorates colitis." in: The EMBO journal, Vol. 35, Issue 6, pp. 685-98, 2016

Bilder

Produktdetails anti-TLR6 Antikörper Target Details TLR6 Anwendungsinformationen Handhabung Referenzen für anti-TLR6 Antikörper (ABIN749573) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 6 (TLR6) (AA 340-380) antibody (ABIN749573) Formalin-fixed and paraffin embedded mouse stomach labeled with Anti-TLR6/CD286 Polyc...
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 6 (TLR6) (AA 340-380) antibody (ABIN749573) Rat splenocytes stained with Anti- TLR6/CD286 Polyclonal Antibody, PE-CY5.5 Conjugate...
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 6 (TLR6) (AA 340-380) antibody (ABIN749573) Rat splenocytes stained with Anti- TLR6/CD286 Polyclonal Antibody, PE-CY5.5 Conjugate...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Toll-Like Receptor 6 (TLR6) (AA 340-380) antibody (ABIN749573) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-TLR6 Poly...
Western Blotting (WB) image for anti-Toll-Like Receptor 6 (TLR6) (AA 340-380) antibody (ABIN749573) Rat spleen lysates probed with TLR6 Polyclonal Antibody, unconjugated at 1:300 overn...
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 6 (TLR6) (AA 340-380) antibody (ABIN749573) Mouse splenocytes probed with TLR6 Polyclonal Antibody, Unconjugated at 1:100 for 30...
Western Blotting (WB) image for anti-Toll-Like Receptor 6 (TLR6) (AA 340-380) antibody (ABIN749573) Mouse thymus lysates probed with TLR6 Polyclonal Antibody, unconjugated at 1:300 ove...
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 6 (TLR6) (AA 340-380) antibody (ABIN749573) A549 cells probed with TLR6 Polyclonal Antibody, Unconjugated at 1:100 for 30 minute...