anti-Maus TLR5 Antikörper für Immunofluorescence

Recommended TLR5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 5 (TLR5) Antikörper
  • TLR-5
  • sleb1
  • til3
  • tlr-5
  • SLEB1
  • TIL3
  • toll like receptor 5
  • toll like receptor 5 L homeolog
  • toll-like receptor 5
  • TLR5
  • tlr5.L
  • tlr-5
  • Tlr5
Epitop
C-Term
32
15
15
11
11
11
11
10
10
7
7
7
5
5
5
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
Reaktivität
Human, Maus
255
150
49
45
5
2
2
2
1
Wirt
Kaninchen
170
101
4
Klonalität
Polyklonal
Konjugat
Dieser TLR5 Antikörper ist unkonjugiert
24
17
12
9
8
5
5
4
4
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
211
96
85
78
66
19
16
13
11
10
6
4
3
1
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN265142
$ 610.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN302879 IF IHC (p) WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN5555337 EIA IF WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN4360251 ELISA ICC IF WB Rabbit Anmelden zum Anzeigen Polyclonal 0

General

Antigen Toll-Like Receptor 5 (TLR5) Antikörper
Epitop C-Term
(32), (15), (15), (11), (11), (11), (11), (10), (10), (7), (7), (7), (5), (5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reaktivität Human, Maus
(255), (150), (49), (45), (5), (2), (2), (2), (1)
Wirt Kaninchen
(170), (101), (4)
Klonalität
Polyklonal
Konjugat Dieser TLR5 Antikörper ist unkonjugiert
(24), (17), (12), (9), (8), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (IF), Western Blotting (WB)
(211), (96), (85), (78), (66), (19), (16), (13), (11), (10), (6), (4), (3), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR5 Antikörper

Target Details TLR5 Anwendungsinformationen Handhabung Referenzen für anti-TLR5 Antikörper (ABIN265142) Bilder
Spezifität This antibody detects TLR5.
Reinigung Purified
Immunogen Peptide corresponding to 15 amino acids near the carboxy terminus of human TLR5
Isotyp IgG
Plasmids, Primers & others

Target Details TLR5

Produktdetails anti-TLR5 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TLR5 Antikörper (ABIN265142) Bilder zurück nach oben
Antigen
Andere Bezeichnung TLR5 (TLR5 Antibody Abstract)
Hintergrund Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (3) so the organism can respond to potential infection. TLR5 recognizes flagellin from both Gram-positive and Gram-negative bacteria and will cause the activation of NF-κB, leading to the activation of TNF-? and other cytokines (4). A common TLR5 stop codon polymorphism that disrupts TLR5 signaling is associated with susceptibility to Legionnaires' disease and demonstrates the importance of TLR5 in the innate immune response (5). Found in the membrane, TLR5 is hghly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis (6).Synonyms: TIL3, Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3
Gen-ID 7100
NCBI Accession NP_003259
UniProt O60602
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR5 Antikörper Target Details TLR5 Handhabung Referenzen für anti-TLR5 Antikörper (ABIN265142) Bilder zurück nach oben
Applikations-hinweise Western Blot: 1-2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR5 Antikörper Target Details TLR5 Anwendungsinformationen Referenzen für anti-TLR5 Antikörper (ABIN265142) Bilder zurück nach oben
Buffer Phosphate buffered saline with 0.02 % Sodium Azide as preservative.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung -20 °C
Informationen zur Lagerung Store the antibody (in aliquots) at -20 °C. Can be shipped at 2-8 °C.

Referenzen für anti-TLR5 Antikörper (ABIN265142)

Produktdetails anti-TLR5 Antikörper Target Details TLR5 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

McGettrick, ONeill: "The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction." in: Molecular immunology, Vol. 41, Issue 6-7, pp. 577-82, 2004

Takeda, Kaisho, Akira: "Toll-like receptors." in: Annual review of immunology, Vol. 21, pp. 335-76, 2003

Hawn, Verbon, Lettinga, Zhao, Li, Laws, Skerrett, Beutler, Schroeder, Nachman, Ozinsky, Smith, Aderem: "A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease." in: The Journal of experimental medicine, Vol. 198, Issue 10, pp. 1563-72, 2003

Janeway, Medzhitov: "Innate immune recognition." in: Annual review of immunology, Vol. 20, pp. 197-216, 2002

Hayashi, Smith, Ozinsky, Hawn, Yi, Goodlett, Eng, Akira, Underhill, Aderem: "The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5." in: Nature, Vol. 410, Issue 6832, pp. 1099-103, 2001

Bilder

Produktdetails anti-TLR5 Antikörper Target Details TLR5 Anwendungsinformationen Handhabung Referenzen für anti-TLR5 Antikörper (ABIN265142) zurück nach oben
Bilder des Herstellers
 image for anti-Toll-Like Receptor 5 (TLR5) (C-Term) antibody (ABIN265142) anti-Toll-Like Receptor 5 (TLR5) (C-Term) antibody