anti-Schwein TLR4 Antikörper für Immunoprecipitation

Recommended TLR4 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 4 (TLR4) Antikörper
  • ARMD10
  • CD284
  • TLR-4
  • TOLL
  • Lps
  • Ly87
  • Ran/M1
  • Rasl2-8
  • toll like receptor 4
  • toll-like receptor 4
  • TLR4
  • Tlr4
Reaktivität
Hund, Meerschweinchen, Human, Affe, Schwein
555
275
174
93
71
71
63
27
12
9
4
2
1
1
Wirt
Maus
340
272
47
7
Klonalität
Monoklonal
Konjugat
Dieser TLR4 Antikörper ist unkonjugiert
49
47
47
23
15
14
13
10
9
9
8
6
6
6
6
6
6
6
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
392
340
186
137
130
124
98
91
34
31
27
26
26
21
20
16
14
8
7
4
4
3
2
1
1
1
Hersteller
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Produktnummer ABIN119332
$ 253.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2479746 FACS IP WB Mouse IgG2a Anmelden zum Anzeigen HTA125 4
1 ABIN119331 FACS IP WB Mouse IgG2a Anmelden zum Anzeigen HTA125 2
1 ABIN119330 Func FACS IP WB Mouse IgG2a Anmelden zum Anzeigen HTA125 2
1 ABIN2479755 Func FACS IP WB Mouse IgG2a Anmelden zum Anzeigen HTA125 4
1 ABIN576473 FACS IP WB PE Mouse IgG2a Anmelden zum Anzeigen 0
1 ABIN206338 FACS IP WB Mouse IgG2a Anmelden zum Anzeigen 0
1 ABIN206473 FACS IP WB FITC Mouse IgG2a Anmelden zum Anzeigen 0
1 ABIN206336 FACS IP WB Biotin Mouse IgG2a Anmelden zum Anzeigen 0
1 ABIN217676 Func FACS IP WB Mouse IgG2a Anmelden zum Anzeigen 0
1 ABIN319978 FACS IP Mouse IgG2a Anmelden zum Anzeigen HTA125 0

General

Antigen Toll-Like Receptor 4 (TLR4) Antikörper
Reaktivität Hund, Meerschweinchen, Human, Affe, Schwein
(555), (275), (174), (93), (71), (71), (63), (27), (12), (9), (4), (2), (1), (1)
Wirt Maus
(340), (272), (47), (7)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser TLR4 Antikörper ist unkonjugiert
(49), (47), (47), (23), (15), (14), (13), (10), (9), (9), (8), (6), (6), (6), (6), (6), (6), (6), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
(392), (340), (186), (137), (130), (124), (98), (91), (34), (31), (27), (26), (26), (21), (20), (16), (14), (8), (7), (4), (4), (3), (2), (1), (1), (1)
Pubmed 9 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR4 Antikörper

Target Details TLR4 Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN119332) Bilder
Reinigung Affinity Chromatography on Protein G
Immunogen Ba/F3 cell line expressing TLR4. Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
Klon HTA125
Isotyp IgG2a
Plasmids, Primers & others

Target Details TLR4

Produktdetails anti-TLR4 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN119332) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD284 / TLR4 (TLR4 Antibody Abstract)
Hintergrund TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 Molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS.Synonyms: Toll-like receptor 4
NCBI Accession NM_138554
UniProt O00206
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Handhabung Referenzen für anti-TLR4 Antikörper (ABIN119332) Bilder zurück nach oben
Applikations-hinweise Flow cytometry: 1/10-1/25, use 10 μL of the suggested working solution to label 10^6 cells or 100 μL whole blood. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Referenzen für anti-TLR4 Antikörper (ABIN119332) Bilder zurück nach oben
Konzentration 1.0 mg/mL
Buffer PBS containing 0.09 % Sodium Azide as preservative.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-TLR4 Antikörper (ABIN119332)

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

de Kleer, Vercoulen, Klein, Meerding, Albani, van der Zee, Sawitzki, Hamann, Kuis, Prakken: "CD30 discriminates heat shock protein 60-induced FOXP3+ CD4+ T cells with a regulatory phenotype." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 4, pp. 2071-9, 2010

Brännström, Sellin, Holmfeldt, Brattsand, Gullberg: "The Schistosoma mansoni protein Sm16/SmSLP/SmSPO-1 assembles into a nine-subunit oligomer with potential To inhibit Toll-like receptor signaling." in: Infection and immunity, Vol. 77, Issue 3, pp. 1144-54, 2009

Devaney, Greene, Taggart, Carroll, ONeill, McElvaney: "Neutrophil elastase up-regulates interleukin-8 via toll-like receptor 4." in: FEBS letters, Vol. 544, Issue 1-3, pp. 129-32, 2003

Bieback, Lien, Klagge, Avota, Schneider-Schaulies, Duprex, Wagner, Kirschning, Ter Meulen, Schneider-Schaulies: "Hemagglutinin protein of wild-type measles virus activates toll-like receptor 2 signaling." in: Journal of virology, Vol. 76, Issue 17, pp. 8729-36, 2002

Triantafilou, Miyake, Golenbock, Triantafilou: "Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation." in: Journal of cell science, Vol. 115, Issue Pt 12, pp. 2603-11, 2002

Yang, Tamai, Akashi, Takeuchi, Akira, Sugawara, Takada: "Synergistic effect of muramyldipeptide with lipopolysaccharide or lipoteichoic acid to induce inflammatory cytokines in human monocytic cells in culture." in: Infection and immunity, Vol. 69, Issue 4, pp. 2045-53, 2001

Kawahara, Teshima, Oka, Sugiyama, Kishi, Rokutan: "Type I Helicobacter pylori lipopolysaccharide stimulates toll-like receptor 4 and activates mitogen oxidase 1 in gastric pit cells." in: Infection and immunity, Vol. 69, Issue 7, pp. 4382-9, 2001

Jiang, Akashi, Miyake, Petty: "Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 7, pp. 3541-4, 2000

Shimazu, Akashi, Ogata, Nagai, Fukudome, Miyake, Kimoto: "MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4." in: The Journal of experimental medicine, Vol. 189, Issue 11, pp. 1777-82, 1999