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4 | ABIN2659215 | FACS IP Neut WB | PE-Cy7 | Rat | IgG2a kappa | Anmelden zum Anzeigen | SA15-21 | 8 | ||
1 | ABIN2659216 | FACS IP Neut WB | PE-Cy7 | Rat | IgG2a kappa | Anmelden zum Anzeigen | SA15-21 | 8 | ||
0.74174976 | ABIN4360163 | BP CyTOF FACS Neut | Rat | IgG2a kappa | Anmelden zum Anzeigen | MTS510 | 11 | |||
-12.75825 | ABIN4360180 | BP FACS Neut | PerCP | Rat | IgG2a kappa | Anmelden zum Anzeigen | MTS510 | 0 | ||
-12.75825 | ABIN4360162 | BP CyTOF FACS Neut | Rat | IgG2a kappa | Anmelden zum Anzeigen | MTS510 | 0 | |||
-12.75825 | ABIN4360166 | BP CyTOF FACS ICC IF IHC (p) Neut WB | Mouse | IgG2b kappa | Anmelden zum Anzeigen | 76B357-1 | 0 |
General |
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Antigen | Toll-Like Receptor 4 (TLR4) Antikörper |
Reaktivität | Human, Maus, Ratte (Rattus) Alternativen |
Wirt | Maus Alternativen |
Klonalität (Klon) | |
Konjugat | Dieser TLR4 Antikörper ist unkonjugiert Alternativen |
Applikation |
Blocking Peptide (BP), Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Neutralization (Neut), Western Blotting (WB)
Alternativen
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24 Publikationen vorhanden |
Hersteller | Anmelden zum Anzeigen |
Produktdetails anti-TLR4 AntikörperTarget Details TLR4 Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN4360167) Bilder |
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Spezifität | The amino acid sequence used has 100 % identity in human, chimp, baboon, chinese hamster, and rat, 93 % identity in bovine and pig, 85 % identity in sheep and 78 % identity in cat, horse and mouse. |
Reinigung | Protein G purified |
Immunogen | This antibody was developed against a portion of amino acids 100-200 of human TLR4 (NP_612564). |
Klon | 76B357-1 |
Isotyp | IgG2b kappa |
Plasmids, Primers & others | |
Target Details TLR4Produktdetails anti-TLR4 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN4360167) Bilder zurück nach oben |
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Antigen | |
Andere Bezeichnung | TLR4 (TLR4 Antibody Abstract) |
Hintergrund | Gene Symbol: TLR4 |
Gen-ID | 7099 |
NCBI Accession | NP_612564 |
Pathways | TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades |
AnwendungsinformationenProduktdetails anti-TLR4 Antikörper Target Details TLR4 Handhabung Referenzen für anti-TLR4 Antikörper (ABIN4360167) Bilder zurück nach oben |
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Applikations-hinweise | Western Blot 1-3 μg/mL, Flow Cytometry 1 μL/1 million cells, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 5 μg/mL, Blocking/Neutralizing, Flow (Cell Surface), CyTOF-readyUse in blocking/neutralizing reported in scientific literature (PMID 26063617). Use in Flow-cell surface reported in multiple pieces of scientific literature |
Kommentare |
The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo. |
Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Referenzen für anti-TLR4 Antikörper (ABIN4360167) Bilder zurück nach oben |
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Format | Liquid |
Buffer |
PBS Buffer contains: No Preservative |
Konservierungs-mittel | Without preservative |
Lagerung | 4 °C,-20 °C |
Informationen zur Lagerung | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Referenzen für anti-TLR4 Antikörper (ABIN4360167)Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Handhabung Bilder zurück nach oben |
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Produkt verwendet in: |
Haricharan, Brown: "TLR4 has a TP53-dependent dual role in regulating breast cancer cell growth." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 25, pp. E3216-25, 2015 (Probematerial (Species): Human). Weitere Details: Blocking Peptide,Neutralization Degraaf, Zasłona, Bourdonnay, Peters-Golden: "Prostaglandin E2 reduces Toll-like receptor 4 expression in alveolar macrophages by inhibition of translation." in: American journal of respiratory cell and molecular biology, Vol. 51, Issue 2, pp. 242-50, 2014 (Probematerial (Species): Rat (Rattus)). Weitere Details: Cell Sorting McCulloch, Brown, Mabbott: "Ablation of the cellular prion protein, PrPC, specifically on follicular dendritic cells has no effect on their maturation or function." in: Immunology, Vol. 138, Issue 3, pp. 246-57, 2013 (Probematerial (Species): Mouse (Murine)). Weitere Details: Immunohistochemistry (Frozen Sections) Jazaeri, Tavangar, Ghazi-Khansari, Khorramizadeh, Mani, Dehpour: "Cirrhosis is associated with development of tolerance to cardiac chronotropic effect of endotoxin in rats." in: Liver international : official journal of the International Association for the Study of the Liver, Vol. 33, Issue 3, pp. 368-74, 2013 Semar, Klotz, Letiembre, Van Ginneken, Braun, Jost, Bischof, Lammers, Liu, Fassbender, Wyss-Coray, Kirchhoff, Schäfer: "Changes of the enteric nervous system in amyloid-β protein precursor transgenic mice correlate with disease progression." in: Journal of Alzheimer's disease : JAD, Vol. 36, Issue 1, pp. 7-20, 2013 Abdi, Mutis, Garssen, Redegeld: "Characterization of the Toll-like receptor expression profile in human multiple myeloma cells." in: PLoS ONE, Vol. 8, Issue 4, pp. e60671, 2013 Janardhanam, Prakasam, Swaminathan, Kodumudi, Zunt, Srinivasan: "Differential expression of TLR-2 and TLR-4 in the epithelial cells in oral lichen planus." in: Archives of oral biology, Vol. 57, Issue 5, pp. 495-502, 2012 Liu, Fatheree, Mangalat, Rhoads: "Lactobacillus reuteri strains reduce incidence and severity of experimental necrotizing enterocolitis via modulation of TLR4 and NF-κB signaling in the intestine." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 302, Issue 6, pp. G608-17, 2012 Zheng, Yang, Rong, Yuan, Ma, Wang, Shen, Cui: "CD74 and macrophage migration inhibitory factor as therapeutic targets in gastric cancer." in: World journal of gastroenterology : WJG, Vol. 18, Issue 18, pp. 2253-61, 2012 (Probematerial (Species): Human). Weitere Details: Western Blotting,Immunohistochemistry (Paraffin-embedded Sections) Hsiao, Kao, Huang, Chuang: "Toll-like receptor-4 agonist inhibits motility and invasion of hepatoblastoma HepG2 cells in vitro." in: Pediatric blood & cancer, Vol. 60, Issue 2, pp. 248-53, 2012 Nowicki, Kosacka, Serke, Blüher, Spanel-Borowski: "Altered sciatic nerve fiber morphology and endoneural microvessels in mouse models relevant for obesity, peripheral diabetic polyneuropathy, and the metabolic syndrome." in: Journal of neuroscience research, Vol. 90, Issue 1, pp. 122-31, 2011 Weile, Josefsen, Buschard: "Glucose activation of islets of Langerhans up-regulates Toll-like receptor 5: possible mechanism of protection." in: Clinical and experimental immunology, Vol. 166, Issue 2, pp. 251-7, 2011 Wu, Meng, Jiang, Zhang, Trippler, Broering, Bucchi, Krux, Dittmer, Yang, Roggendorf, Gerken, Lu, Schlaak: "Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific." in: Immunology, Vol. 129, Issue 3, pp. 363-74, 2010 Johnston, Wang, Catarino, Ball, Phan, MacDonald, McKay: "Extracts of the rat tapeworm, Hymenolepis diminuta, suppress macrophage activation in vitro and alleviate chemically induced colitis in mice." in: Infection and immunity, Vol. 78, Issue 3, pp. 1364-75, 2010 Hafez, Hayes, Goldrick, Grencis, Roberts et al.: "The K5 capsule of Escherichia coli strain Nissle 1917 is important in stimulating expression of Toll-like receptor 5, CD14, MyD88, and TRIF together with the induction of interleukin-8 expression via ..." in: Infection and immunity, Vol. 78, Issue 5, pp. 2153-62, 2010 Brandau, Jakob, Hemeda, Bruderek, Janeschik, Bootz, Lang: "Tissue-resident mesenchymal stem cells attract peripheral blood neutrophils and enhance their inflammatory activity in response to microbial challenge." in: Journal of leukocyte biology, Vol. 88, Issue 5, pp. 1005-15, 2010 (Probematerial (Species): Human). Weitere Details: Flow Cytometry Lunardi, Bason, Dolcino, Navone, Simone, Saverino, Frulloni, Tinazzi, Peterlana, Corrocher, Puccetti et al.: "Antiflagellin antibodies recognize the autoantigens Toll-Like Receptor 5 and Pals 1-associated tight junction protein and induce monocytes activation and increased intestinal permeability in Crohn's ..." in: Journal of internal medicine, Vol. 265, Issue 2, pp. 250-65, 2009 Link, Selejan, Maack, Lenz, Böhm: "Phosphodiesterase 4 inhibition but not beta-adrenergic stimulation suppresses tumor necrosis factor-alpha release in peripheral blood mononuclear cells in septic shock." in: Critical care, Vol. 12, Issue 6, pp. R159, 2009 Worku, Morris: "Binding of different forms of lipopolysaccharide and gene expression in bovine blood neutrophils." in: Journal of dairy science, Vol. 92, Issue 7, pp. 3185-93, 2009 Nowicki, Müller, Serke, Kosacka, Vilser, Ricken, Spanel-Borowski: "Oxidized low-density lipoprotein (oxLDL)-induced cell death in dorsal root ganglion cell cultures depends not on the lectin-like oxLDL receptor-1 but on the toll-like receptor-4." in: Journal of neuroscience research, Vol. 88, Issue 2, pp. 403-12, 2009 (Probematerial (Species): Rat (Rattus)). Weitere Details: Immunocytochemistry,Immunofluorescence |
BilderProduktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN4360167) zurück nach oben |
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Bilder des Herstellers |
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