anti-Human TLR4 Antikörper für Neutralization

Recommended TLR4 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 4 (TLR4) Antikörper
  • ARMD10
  • CD284
  • TLR-4
  • TOLL
  • Lps
  • Ly87
  • Ran/M1
  • Rasl2-8
  • toll like receptor 4
  • toll-like receptor 4
  • TLR4
  • Tlr4
Epitop
AA 24-631
59
31
28
25
16
15
15
15
14
13
13
11
10
9
8
7
6
5
5
5
5
5
5
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
568
291
177
96
72
72
64
27
12
10
4
2
1
1
Wirt
Ziege
343
283
58
6
Klonalität
Polyklonal
Konjugat
Dieser TLR4 Antikörper ist unkonjugiert
50
47
47
23
19
16
15
11
10
10
8
8
8
8
7
7
6
6
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Neutralization (Neut), Western Blotting (WB)
410
344
189
140
131
124
100
94
34
31
27
26
25
21
21
16
13
8
7
4
4
3
2
2
1
1
Hersteller
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Bilder

Produktnummer ABIN4899843
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN4360167 BP CyTOF FACS ICC IF IHC (p) Neut WB Mouse IgG2b kappa Anmelden zum Anzeigen 76B357-1 24
1 ABIN4360113 BP CyTOF FACS Func ICC IF IP in vitro Neut Mouse IgG2a Anmelden zum Anzeigen HTA125 45
1 ABIN208040 ICC FACS IP Neut Mouse IgG2a Anmelden zum Anzeigen HTA125 0
1 ABIN4360119 BP CyTOF FACS ICC IF IP in vitro Neut Mouse IgG2a Anmelden zum Anzeigen HTA125 22
1 ABIN4360158 BP ELISA FACS ICC IF IP Neut Biotin Mouse IgG2a Anmelden zum Anzeigen HTA125 18
1 ABIN960441 FACS IP Neut ELISA Biotin Mouse IgG2a, kappa Anmelden zum Anzeigen HTA125 0
1 ABIN198155 FACS IHC IHC (fro) IP Neut Mouse IgG2a Anmelden zum Anzeigen HTA125 0
1 ABIN198149 FACS IP Neut PE Mouse IgG2a, kappa Anmelden zum Anzeigen 0
1 ABIN961106 FACS IP Neut Mouse IgG2a Anmelden zum Anzeigen HTA125 0
1 ABIN4360215 BP FACS ICC IF IP in vitro Neut Alexa Fluor 405 Mouse IgG2a Anmelden zum Anzeigen HTA125 0
1 ABIN4360216 BP FACS ICC IF IP in vitro Neut Alexa Fluor 647 Mouse IgG2a Anmelden zum Anzeigen HTA125 0
1 ABIN4360218 BP FACS ICC IF IP in vitro Neut APC Mouse IgG2a Anmelden zum Anzeigen HTA125 0
1 ABIN4360219 BP FACS ICC IF IP in vitro Neut DyLight 680 Mouse IgG2a Anmelden zum Anzeigen HTA125 0
1 ABIN4360220 BP FACS ICC IF IP in vitro Neut DyLight 488 Mouse IgG2a Anmelden zum Anzeigen HTA125 0
1 ABIN4360221 BP FACS ICC IF IP in vitro Neut DyLight 755 Mouse IgG2a Anmelden zum Anzeigen HTA125 0
1 ABIN2376302 FACS IP Neut PE Mouse IgG2a kappa Anmelden zum Anzeigen 4H272 0
1 ABIN2376285 IC FACS IF IP Neut Mouse IgG2a kappa Anmelden zum Anzeigen 4H272 0
1 ABIN2376286 FACS IP Neut IHC WB Rabbit AA 6-169 Anmelden zum Anzeigen Polyclonal 0
1 ABIN4360217 BP FACS ICC IF IP in vitro Neut Alexa Fluor 700 Mouse IgG2a Anmelden zum Anzeigen HTA125 0
1 ABIN4360222 BP FACS ICC IF IP in vitro Neut PerCP Mouse IgG2a Anmelden zum Anzeigen HTA125 0

General

Antigen Toll-Like Receptor 4 (TLR4) Antikörper
Epitop AA 24-631
(59), (31), (28), (25), (16), (15), (15), (15), (14), (13), (13), (11), (10), (9), (8), (7), (6), (5), (5), (5), (5), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(568), (291), (177), (96), (72), (72), (64), (27), (12), (10), (4), (2), (1), (1)
Wirt Ziege
(343), (283), (58), (6)
Klonalität
Polyklonal
Konjugat Dieser TLR4 Antikörper ist unkonjugiert
(50), (47), (47), (23), (19), (16), (15), (11), (10), (10), (8), (8), (8), (8), (7), (7), (6), (6), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Neutralization (Neut), Western Blotting (WB)
(410), (344), (189), (140), (131), (124), (100), (94), (34), (31), (27), (26), (25), (21), (21), (16), (13), (8), (7), (4), (4), (3), (2), (2), (1), (1)
Pubmed 13 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR4 Antikörper

Target Details TLR4 Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN4899843) Bilder
Spezifität Detects human TLR4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 30 % cross-reactivity with recombinant mouse (rm) TLR4 is observed and less than 5 % cross-reactivity with recombinant human (rh) TLR1, rhTLR2, rhTLR3 and rmTLR6 is observed.
Reinigung Immunogen affinity purified
Sterilität 0.2 μm filtered
Endotoxin-Niveau <0.10 EU per 1 μg of the antibody by the LAL method.
Immunogen Mouse myeloma cell line NS0-derived recombinant human TLR4, Glu24-Lys631, Accession # O00206
Isotyp IgG
Plasmids, Primers & others

Target Details TLR4

Produktdetails anti-TLR4 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN4899843) Bilder zurück nach oben
Antigen
Andere Bezeichnung TLR4 (TLR4 Antibody Abstract)
Hintergrund Alternative Names: ARMD10, CD284, CD284 antigen, hTollhomolog of Drosophila toll, TOLL, toll-like receptor 4
Gen-ID 7099
UniProt O00206
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Handhabung Referenzen für anti-TLR4 Antikörper (ABIN4899843) Bilder zurück nach oben
Applikations-hinweise Western Blot 1 μg/mL
Flow Cytometry 2.5 μg/10^6 cells
Immunohistochemistry 5-15 μg/mL
Neutralization 1.5-7.5 μg/mL
Immunocytochemistry 5-15 μg/mL
CyTOF-ready
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Referenzen für anti-TLR4 Antikörper (ABIN4899843) Bilder zurück nach oben
Rekonstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Konservierungs-mittel Without preservative
Lagerung 4 °C,-20 °C,-80 °C
Informationen zur Lagerung Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Haltbarkeit 12 months

Referenzen für anti-TLR4 Antikörper (ABIN4899843)

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Sandri, Urban Borbely, Fernandes, de Oliveira, Knebel, Ruano, Zugaib, Filippin-Monteiro, Bevilacqua, Campa: "Serum amyloid A in the placenta and its role in trophoblast invasion." in: PLoS ONE, Vol. 9, Issue 3, pp. e90881, 2016 Von den Autoren verwendete Methode: Functional Studies (Func) (Probematerial (Species): Human).

Ben Haij, Planès, Leghmari, Serrero, Delobel, Izopet, BenMohamed, Bahraoui: "HIV-1 Tat Protein Induces Production of Proinflammatory Cytokines by Human Dendritic Cells and Monocytes/Macrophages through Engagement of TLR4-MD2-CD14 Complex and Activation of NF-κB Pathway." in: PLoS ONE, Vol. 10, Issue 6, pp. e0129425, 2015 Von den Autoren verwendete Methode: Flow Cytometry (FACS), Flow Cytometry (FACS) (Probematerial (Species): Human).

Avlas, Bragg, Fuks, Nicholson, Farkash, Porat, Aravot, Levy-Drummer, Cohen, Shainberg, Arad, Hochhauser: "TLR4 Expression Is Associated with Left Ventricular Dysfunction in Patients Undergoing Coronary Artery Bypass Surgery." in: PLoS ONE, Vol. 10, Issue 6, pp. e0120175, 2015 Von den Autoren verwendete Methode: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Frozen Sections) (IHC (fro)) (Probematerial (Species): Human).

Su, Yang, Lee, Sheu, Hsu, Lin, Chow: "The C-terminal disulfide bonds of Helicobacter pylori GroES are critical for IL-8 secretion via the TLR4-dependent pathway in gastric epithelial cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 8, pp. 3997-4007, 2015 Von den Autoren verwendete Methode: Immunoprecipitation (IP), Immunoprecipitation (IP) (Probematerial (Species): Helicobacter pylori).

Vogel, Börger, Peters, Förster, Liebfried, Metzger, Meisel, Däubener, Trapp, Fischer, Gawaz, Sorg: "Necrotic cell-derived high mobility group box 1 attracts antigen-presenting cells but inhibits hepatocyte growth factor-mediated tropism of mesenchymal stem cells for apoptotic cell death." in: Cell death and differentiation, Vol. 22, Issue 7, pp. 1219-30, 2015 Von den Autoren verwendete Methode: Neutralization (Neut), Neutralization (Neut) (Probematerial (Species): Mouse (Murine)).

Kelsh, You, Horzempa, Zheng, McKeown-Longo: "Regulation of the innate immune response by fibronectin: synergism between the III-1 and EDA domains." in: PLoS ONE, Vol. 9, Issue 7, pp. e102974, 2015 Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Alizadeh, Tripathi, Abdi, Smith: "Pathogenic strains of Acanthamoeba are recognized by TLR4 and initiated inflammatory responses in the cornea." in: PLoS ONE, Vol. 9, Issue 3, pp. e92375, 2014 Von den Autoren verwendete Methode: Neutralization (Neut), Neutralization (Neut) (Probematerial (Species): Human).

Vogel, Chatterjee, Metzger, Borst, Geisler, Seizer, Müller, Mack, Schumann, Bhring, Lang, Sorg, Langer, Gawaz et al.: "Activated platelets interfere with recruitment of mesenchymal stem cells to apoptotic cardiac cells via high mobility group box 1/Toll-like receptor 4-mediated down-regulation of hepatocyte growth ..." in: The Journal of biological chemistry, Vol. 289, Issue 16, pp. 11068-82, 2014 Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Mogami, Keller, Shi, Word: "Effect of thrombin on human amnion mesenchymal cells, mouse fetal membranes, and preterm birth." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13295-307, 2014 Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Mogami, Kishore, Shi, Keller, Akgul, Word: "Fetal fibronectin signaling induces matrix metalloproteases and cyclooxygenase-2 (COX-2) in amnion cells and preterm birth in mice." in: The Journal of biological chemistry, Vol. 288, Issue 3, pp. 1953-66, 2013 Von den Autoren verwendete Methode: Neutralization (Neut), Neutralization (Neut) (Probematerial (Species): Human).

Zhao, Anand, Ganju: "Slit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 1, pp. 385-93, 2013 Von den Autoren verwendete Methode: Neutralization (Neut), Neutralization (Neut) (Probematerial (Species): Human).

Lumsden, Nelson, Dispenza, Gilliland, Cong, Zaenglein, Thiboutot: "Isotretinoin increases skin-surface levels of neutrophil gelatinase-associated lipocalin in patients treated for severe acne." in: The British journal of dermatology, Vol. 165, Issue 2, pp. 302-10, 2011 Von den Autoren verwendete Methode: Neutralization (Neut), Neutralization (Neut) (Probematerial (Species): Human).

Zunt, Burton, Goldblatt, Dobbins, Srinivasan: "Soluble forms of Toll-like receptor 4 are present in human saliva and modulate tumour necrosis factor-alpha secretion by macrophage-like cells." in: Clinical and experimental immunology, Vol. 156, Issue 2, pp. 285-93, 2009 Von den Autoren verwendete Methode: Western Blotting (WB), Western Blotting (WB) (Probematerial (Species): Human).

Bilder

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN4899843) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Toll-Like Receptor 4 (TLR4) (AA 24-631) antibody (ABIN4899843) Detection of Human TLR4 by Western Blot. Western blot shows lysates of human placenta...
Neutralization (Neut) image for anti-Toll-Like Receptor 4 (TLR4) (AA 24-631) antibody (ABIN4899843) IL-8 Secretion Induced by LPS and Neutralization by Human TLR4 Antibody. Lipopolysach...
Immunocytochemistry (ICC) image for anti-Toll-Like Receptor 4 (TLR4) (AA 24-631) antibody (ABIN4899843) TLR4 in Human PBMCs. TLR4 was detected in immersion fixed human peripheral blood mono...
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 4 (TLR4) (AA 24-631) antibody (ABIN4899843) TLR4 in Human Prostate. TLR4 was detected in immersion fixed paraffin-embedded sectio...