anti-Human TLR4 Antikörper für Functional Studies

Recommended TLR4 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 4 (TLR4) Antikörper
  • ARMD10
  • CD284
  • TLR-4
  • TOLL
  • Lps
  • Ly87
  • Ran/M1
  • Rasl2-8
  • toll like receptor 4
  • toll-like receptor 4
  • TLR4
  • Tlr4
Reaktivität
Hund, Human
569
291
178
96
73
73
65
27
12
10
4
2
1
1
Wirt
Maus
343
283
58
7
Klonalität
Monoklonal
Konjugat
Dieser TLR4 Antikörper ist unkonjugiert
50
47
47
23
19
16
15
11
10
10
8
8
8
8
7
7
6
6
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Blocking Peptide (BP), Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Functional Studies (Func), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), In vitro Assay (in vitro), Neutralization (Neut)
413
345
187
140
131
125
100
93
34
31
27
26
25
21
20
15
13
8
7
4
4
3
2
2
1
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN4360113
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN119330 Func FACS IP WB Mouse IgG2a Anmelden zum Anzeigen HTA125 2
1 ABIN2479755 Func FACS IP WB Mouse IgG2a Anmelden zum Anzeigen HTA125 4
1 ABIN198147 Func FACS IP ELISA Biotin Mouse IgG2a Anmelden zum Anzeigen 0
1 ABIN198151 Func FACS IP Mouse IgG2a Anmelden zum Anzeigen 0
1 ABIN4964343 FACS Func IA ICC IF IP WB Mouse IgG2a Anmelden zum Anzeigen HTA1245 0
1 ABIN2191941 Func FACS Biotin Mouse IgG2a Anmelden zum Anzeigen HTA125 8
1 ABIN2191940 Func FACS PE Mouse IgG2a Anmelden zum Anzeigen HTA125 8
1 ABIN2191939 Func FACS PE Mouse IgG2a Anmelden zum Anzeigen HTA125 8
1 ABIN2191938 Func FACS FITC Mouse IgG2a Anmelden zum Anzeigen HTA125 8
1 ABIN1106216 Func FACS Mouse IgG1 Anmelden zum Anzeigen 7-00E-003 0
1 ABIN6252558 FACS Func IF IHC (p) Mouse IgG2a, kappa Anmelden zum Anzeigen TLR4-230 0
1 ABIN217676 Func FACS IP WB Mouse IgG2a Anmelden zum Anzeigen 0
1 ABIN2191937 Func FACS Mouse IgG2a Anmelden zum Anzeigen HTA125 8
1 ABIN1106215 Func FACS Mouse IgG1 Anmelden zum Anzeigen 3C3 0
1 ABIN4360112 BP CyTOF FACS Func ICC IF IP in vitro Neut Mouse IgG2a Anmelden zum Anzeigen HTA125 0
1 ABIN3026986 Func FACS IF IHC (p) Mouse IgG2a, kappa Anmelden zum Anzeigen TLR4-230 0
1 ABIN6297482 FACS Func IF IHC Mouse Anmelden zum Anzeigen 0
1 ABIN3026987 Func FACS IF IHC (p) Mouse IgG2a, kappa Anmelden zum Anzeigen TLR4-230 0
1 ABIN2567452 Func FACS Mouse IgG2a kappa Anmelden zum Anzeigen HTA125 0
1 ABIN2567453 Func FACS Mouse IgG2a kappa Anmelden zum Anzeigen HTA125 0

General

Antigen Toll-Like Receptor 4 (TLR4) Antikörper
Reaktivität Hund, Human
(569), (291), (178), (96), (73), (73), (65), (27), (12), (10), (4), (2), (1), (1)
Wirt Maus
(343), (283), (58), (7)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser TLR4 Antikörper ist unkonjugiert
(50), (47), (47), (23), (19), (16), (15), (11), (10), (10), (8), (8), (8), (8), (7), (7), (6), (6), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Blocking Peptide (BP), Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Functional Studies (Func), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), In vitro Assay (in vitro), Neutralization (Neut)
(413), (345), (187), (140), (131), (125), (100), (93), (34), (31), (27), (26), (25), (21), (20), (15), (13), (8), (7), (4), (4), (3), (2), (2), (1), (1)
Pubmed 45 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR4 Antikörper

Target Details TLR4 Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN4360113) Bilder
Spezifität The has been shown to block the activation of monocytes with LPS (Paik, et al, 2003).
Reinigung Protein G purified
Immunogen This antibody was developed by immunizing mice with Ba/F3 cell line expressing human TLR4 cell surface antigen.
Klon HTA125
Isotyp IgG2a
Plasmids, Primers & others

Target Details TLR4

Produktdetails anti-TLR4 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN4360113) Bilder zurück nach oben
Antigen
Andere Bezeichnung TLR4 (TLR4 Antibody Abstract)
Hintergrund Gene Symbol: TLR4
Gen-ID 7099
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Handhabung Referenzen für anti-TLR4 Antikörper (ABIN4360113) Bilder zurück nach oben
Applikations-hinweise Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation 1:10-1:500, Functional, In vitro assay, Blocking/Neutralizing, CyTOF-readyConfocal Microscopy: see Scheel et al. (2006) for details FA (Neutralization): please see publications. Flow (Cell Surface): 2-5 μg/ 1x10^6 cells IF/ICC: please see Schneeman et al (2005) for details. IP: please see Shimazu et al, 1999 for details Use in vitro assays reported in scientific literature (PMID 24676500) Use in Functional reported in scientific literature (PMID 25412776). Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID 27744428)

Not for use in: Western Blot
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Referenzen für anti-TLR4 Antikörper (ABIN4360113) Bilder zurück nach oben
Format Liquid
Konzentration 1.0 mg/mL
Buffer PBS
Buffer contains: 0.05 % Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Referenzen für anti-TLR4 Antikörper (ABIN4360113)

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Larsson, Tengroth, Xu, Uddman, Kumlien Georén, Cardell: "Substance P represents a novel first-line defense mechanism in the nose." in: The Journal of allergy and clinical immunology, 2017 Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Mouse (Murine)).

Heftrig, Sturm, Oppermann, Kontradowitz, Jurida, Schimunek, Woschek, Marzi, Relja: "Impaired Surface Expression of HLA-DR, TLR2, TLR4, and TLR9 in Ex Vivo-In Vitro Stimulated Monocytes from Severely Injured Trauma Patients." in: Mediators of inflammation, Vol. 2017, pp. 2608349, 2017

Li, Song, Ao, Reece, Cleveland, Dong, Fullerton, Meng: "ADAMTS5 Deficiency in Calcified Aortic Valves Is Associated With Elevated Pro-Osteogenic Activity in Valvular Interstitial Cells." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 37, Issue 7, pp. 1339-1351, 2017 Von den Autoren verwendete Methode: Neutralization (Neut), Western Blotting (WB) (Probematerial (Species): Human).

Pérez-Figueroa, Torres, Sánchez-Zauco, Contreras-Ramos, Alvarez-Arellano, Maldonado-Bernal: "Activation of NLRP3 inflammasome in human neutrophils by Helicobacter pylori infection." in: Innate immunity, Vol. 22, Issue 2, pp. 103-12, 2016 (Probematerial (Species): Human). Weitere Details: In vitro Assay,Blocking Peptide,Neutralization

Kopp, Kupsch, Schromm: "Lipopolysaccharide-binding protein is bound and internalized by host cells and colocalizes with LPS in the cytoplasm: Implications for a role of LBP in intracellular LPS-signaling." in: Biochimica et biophysica acta, Vol. 1863, Issue 4, pp. 660-72, 2016 (Probematerial (Species): Human). Weitere Details: Immunocytochemistry,Flow Cytometry,Immunofluorescence

Schmid, Novacek, Vogelsang, Papay, Primas, Eser, Panzer: "Platelets Toll-like receptor-4 in Crohns disease." in: European journal of clinical investigation, 2016

Imai, Fujita, Kajiya, Ouhara, Yoshimoto, Matsuda, Takeda, Kurihara: "Mobilization of TLR4 Into Lipid Rafts by Aggregatibacter Actinomycetemcomitans in Gingival Epithelial Cells." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 39, Issue 5, pp. 1777-1786, 2016

Moreira, Costa-Pereira, Alves, Marteleto, Ribeiro, Peruhype-Magalhães, Giunchetti, Martins-Filho, Araújo: "Vaccination against canine leishmaniosis increases the phagocytic activity, nitric oxide production and expression of cell activation/migration molecules in neutrophils and monocytes." in: Veterinary parasitology, Vol. 220, pp. 33-45, 2016 Von den Autoren verwendete Methode: Flow Cytometry (FACS)

Song, Fullerton, Ao, Zheng, Zhao, Meng: "BMP-2 and TGF-β1 mediate biglycan-induced pro-osteogenic reprogramming in aortic valve interstitial cells." in: Journal of molecular medicine (Berlin, Germany), Vol. 93, Issue 4, pp. 403-12, 2015 (Probematerial (Species): Human). Weitere Details: Functional Studies,Blocking Peptide,Neutralization

Jamin, Dehoux, Dossier, Fila, Heming, Monteiro, Deschênes: "Toll-like receptor 3 expression and function in childhood idiopathic nephrotic syndrome." in: Clinical and experimental immunology, Vol. 182, Issue 3, pp. 332-45, 2015 Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Youn, Shim, Lee, Ji, Oh, Hong, Lee, Park, Lee, Choi, Chung, Kang: "Detailed pathologic evaluation on endomyocardial biopsy provides long-term prognostic information in patients with acute myocarditis." in: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, Vol. 23, Issue 3, pp. 139-44, 2014 (Probematerial (Species): Human). Weitere Details: Immunohistochemistry (Paraffin-embedded Sections)

Feng, Feng, Xing, Shen, Tan, Huang, Lu, Tao, Zhang, Li, Gu: "Repeated lipopolysaccharide stimulation promotes cellular senescence in human dental pulp stem cells (DPSCs)." in: Cell and tissue research, Vol. 356, Issue 2, pp. 369-80, 2014 (Probematerial (Species): Human). Weitere Details: In vitro Assay,Blocking Peptide,Neutralization

Komine-Aizawa, Hirohata, Aizawa, Abiko, Hayakawa: "Porphyromonas gingivalis lipopolysaccharide inhibits trophoblast invasion in the presence of nicotine." in: Placenta, Vol. 36, Issue 1, pp. 27-33, 2014 Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Rojas-Bernabé, Garcia-Hernández, Maldonado-Bernal, Delegado-Dominguez, Ortega, Gutiérrez-Kobeh, Becker, Aguirre-Garcia: "Leishmania mexicana lipophosphoglycan activates ERK and p38 MAP kinase and induces production of proinflammatory cytokines in human macrophages through TLR2 and TLR4." in: Parasitology, Vol. 141, Issue 6, pp. 788-800, 2014 (Probematerial (Species): Human).

Käbisch, Mejías-Luque, Gerhard, Prinz: "Involvement of Toll-like receptors on Helicobacter pylori-induced immunity." in: PLoS ONE, Vol. 9, Issue 8, pp. e104804, 2014 Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Human).

Yuan, Zhou, Wang, Li, Xie, Zhao, Xu, Shen: "Activation of TLR4 signaling promotes gastric cancer progression by inducing mitochondrial ROS production." in: Cell death & disease, Vol. 4, pp. e794, 2013 (Probematerial (Species): Human).

Harman, Bye, Nasr, Sandgren, Kim, Mercier, Botting, Lewin, Cunningham, Cameron: "Identification of lineage relationships and novel markers of blood and skin human dendritic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 1, pp. 66-79, 2012

Wu, Chi, Hsieh, Luo, Yang: "TLR4-dependent induction of vascular adhesion molecule-1 in rheumatoid arthritis synovial fibroblasts: Roles of cytosolic phospholipase A(2)alpha/cyclooxygenase-2." in: Journal of cellular physiology, Vol. 223, Issue 2, pp. 480-91, 2010

Pillay, Ramakers, Kamp, Loi, Lam, Hietbrink, Leenen, Tool, Pickkers, Koenderman: "Functional heterogeneity and differential priming of circulating neutrophils in human experimental endotoxemia." in: Journal of leukocyte biology, Vol. 88, Issue 1, pp. 211-20, 2010

Matsunaga, Tsuchimori, Matsumoto, Ii: "TAK-242 (resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling, binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules." in: Molecular pharmacology, Vol. 79, Issue 1, pp. 34-41, 2010

Bilder

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN4360113) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 4 (TLR4) antibody (ABIN4360113) Flow Cytometry: TLR4 Antibody (HTA125) - Analysis using the PE conjugate of 7. Stain...
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 4 (TLR4) antibody (ABIN4360113) Flow Cytometry: TLR4 Antibody (HTA125) - Analysis using Azide/BSA FREE version of 7....
Immunoprecipitation (IP) image for anti-Toll-Like Receptor 4 (TLR4) antibody (ABIN4360113) Immunoprecipitation: TLR4 Antibody (HTA125) - Analysis using the Alexa Fluor (R) 647...
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 4 (TLR4) antibody (ABIN4360113) Flow Cytometry: TLR4 Antibody (HTA125) - Analysis using the Alexa Fluor (R) 647 conj...
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 4 (TLR4) antibody (ABIN4360113) Flow Cytometry: TLR4 Antibody (HTA125) - Analysis using Azide/BSA FREE version of 7....
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 4 (TLR4) antibody (ABIN4360113) Flow Cytometry: TLR4 Antibody (HTA125) - Analysis using Azide/BSA FREE version of 7....
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 4 (TLR4) antibody (ABIN4360113) Flow Cytometry: TLR4 Antibody (HTA125) - Analysis using Azide/BSA FREE version of 7....
 image for anti-Toll-Like Receptor 4 (TLR4) antibody (ABIN4360113) Blocking/Neutralizing: TLR4 Antibody (HTA125) - Analysis using Azide Free version of...