anti-Rind (Kuh) TLR4 Antikörper für ELISA

Recommended TLR4 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 4 (TLR4) Antikörper
  • ARMD10
  • CD284
  • TLR-4
  • TOLL
  • Lps
  • Ly87
  • Ran/M1
  • Rasl2-8
  • toll like receptor 4
  • toll-like receptor 4
  • TLR4
  • Tlr4
Epitop
C-Term
59
30
28
25
16
15
15
15
15
14
13
11
11
9
9
7
6
5
5
5
5
5
5
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus), Schaf, Rind (Kuh)
566
288
173
95
71
71
63
27
12
10
4
2
2
1
Wirt
Kaninchen
338
284
59
7
Klonalität
Polyklonal
Konjugat
Dieser TLR4 Antikörper ist unkonjugiert
51
47
47
24
19
16
15
11
10
10
8
8
8
8
7
7
6
6
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
413
341
188
137
128
123
97
94
34
32
27
26
24
21
21
16
14
8
7
4
4
3
2
2
1
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN1585859
$ 377.30
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN5701601 ELISA IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN1093596 ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN2903163 ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN5907847 ELISA IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0

General

Antigen Toll-Like Receptor 4 (TLR4) Antikörper
Epitop C-Term
(59), (30), (28), (25), (16), (15), (15), (15), (15), (14), (13), (11), (11), (9), (9), (7), (6), (5), (5), (5), (5), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus), Schaf, Rind (Kuh)
(566), (288), (173), (95), (71), (71), (63), (27), (12), (10), (4), (2), (2), (1)
Wirt Kaninchen
(338), (284), (59), (7)
Klonalität
Polyklonal
Konjugat Dieser TLR4 Antikörper ist unkonjugiert
(51), (47), (47), (24), (19), (16), (15), (11), (10), (10), (8), (8), (8), (8), (7), (7), (6), (6), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(413), (341), (188), (137), (128), (123), (97), (94), (34), (32), (27), (26), (24), (21), (21), (16), (14), (8), (7), (4), (4), (3), (2), (2), (1), (1)
Pubmed 4 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR4 Antikörper

Target Details TLR4 Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN1585859) Bilder
Kreuzreaktivität Maus, Ratte (Rattus), Schaf, Rind (Kuh)
Reinigung Antibody was purified by Protein-A affinity chromatography.
Immunogen KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of rat TLR4.
Plasmids, Primers & others

Target Details TLR4

Produktdetails anti-TLR4 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN1585859) Bilder zurück nach oben
Antigen
Andere Bezeichnung TLR4 (TLR4 Antibody Abstract)
Hintergrund

Alternate Names: Toll-like receptor 4, hToll, CD284, TLR4

Description: Toll-like receptor family (TLR) has a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLRs recognize pathogen-associated molecular patterns (PAMP) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Toll-like receptor 4 (TLR4) cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6 to lead to NFkB activation, cytokine secretion and inflammatory response. TLR4 is highly expressed in placenta, spleen and peripheral blood leukocytes. Genetic variation in TLR4 is associated with age-related macular degeneration 10 (ARMD10), an irreversible vision loss.

UniProt O00206
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Handhabung Referenzen für anti-TLR4 Antikörper (ABIN1585859) Bilder zurück nach oben
Applikations-hinweise E: 1:500-1:1,000, WB: 1:200-1:500, IHC: 1:100-1:500
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Referenzen für anti-TLR4 Antikörper (ABIN1585859) Bilder zurück nach oben
Format Liquid
Konzentration 1 mg/mL
Buffer Each vial contains 0.1 mg IgG in 0.1 mL (1 mg/mL) of PBS pH 7.4, 25 % glycerol, 1 mg/mL BSA with 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Handhabung Minimize freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Haltbarkeit 12 months

Referenzen für anti-TLR4 Antikörper (ABIN1585859)

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Kulikova, Nizyaeva, Nagovitsina, Lyapin, Loginova, Kan, Tyutyunnik, Tyutyunnik, Schegolev: "Specific Features of TLR4 Expression in Structural Elements of Placenta in Patients with Preeclampsia." in: Bulletin of experimental biology and medicine, Vol. 160, Issue 5, pp. 718-21, 2017

Garcia, Seiva, Carniato, de Mello Júnior, Duran, Macedo, de Oliveira, Romih, Nunes, Nunes, Fávaro: "Increased toll-like receptors and p53 levels regulate apoptosis and angiogenesis in non-muscle invasive bladder cancer: mechanism of action of P-MAPA biological response modifier." in: BMC cancer, Vol. 16, pp. 422, 2017

Lüttgenau, Herzog, Strüve, Latter, Boos, Bruckmaier, Bollwein, Kowalewski: "LPS-mediated effects and spatio-temporal expression of TLR2 and TLR4 in the bovine corpus luteum." in: Reproduction (Cambridge, England), Vol. 151, Issue 4, pp. 391-9, 2016

Garcia, Apolinário, Böckelmann, da Silva Nunes, Duran, Fávaro: "Alterations in ubiquitin ligase Siah-2 and its corepressor N-CoR after P-MAPA immunotherapy and anti-androgen therapy: new therapeutic opportunities for non-muscle invasive bladder cancer." in: International journal of clinical and experimental pathology, Vol. 8, Issue 5, pp. 4427-43, 2015

Bilder

Produktdetails anti-TLR4 Antikörper Target Details TLR4 Anwendungsinformationen Handhabung Referenzen für anti-TLR4 Antikörper (ABIN1585859) zurück nach oben
Bilder des Herstellers
 image for anti-Toll-Like Receptor 4 (TLR4) (C-Term) antibody (ABIN1585859) TLR4 staining in human placenta. Paraffin-embedded human placenta is stained with TLR...
 image for anti-Toll-Like Receptor 4 (TLR4) (C-Term) antibody (ABIN1585859) The TLR4 Antibody is used in Western blot to detect TLR4 in rat liver lysates.