Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Weitere Synonyme anzeigen
Cerebrospinal fluid soluble TLR2 and TLR4 may play a role in HIV/SIV-related neuroinflammation and subsequent neuropathology.
Following a combined in silico/in vitro approach we have discovered TLR2-agonists (AG1-AG4) that activate human and mouse immune cells.
PBMC TLR2 and TLR4 (zeige TLR4 ELISA Kits) were significantly higher in the AFMI group than in the control group and MI group. A similar tendency was also oTLR4 proteinbserved in the expression of downstream signaling proteins. When further analyzed with TLR2 and TLR4 (zeige TLR4 ELISA Kits) antibodies by flow cytometry, PBMC levels also appeared to be higher in AFMI patients than those in MI patients and the healthy control group.In our study
analysis of TLR2 rs5743708, TLR2 rs4696480, TLR4 (zeige TLR4 ELISA Kits) rs4986790, TLR9 (zeige TLR9 ELISA Kits) rs5743836 and TLR9 (zeige TLR9 ELISA Kits) rs352140 SNPs in children with pneumococcal and meningococcal meningitis and their family members; study did not show an association between the analyzed SNPs in TLR2, TLR4 (zeige TLR4 ELISA Kits), and TLR9 (zeige TLR9 ELISA Kits) and susceptibility to develop bacterial meningitis
TLR2 and IL28B (zeige IL28B ELISA Kits) polymorphisms in combination showed a role in the control of HCV viral load and different HCV disease progression.
Data suggest that dendritic cells are sensitive to environmentally relevant level of aflatoxin B1 (AFB1); TLR2 and TLR4 (zeige TLR4 ELISA Kits) are involved in sensing AFB1; expression levels of both TLR2 and TLR4 (zeige TLR4 ELISA Kits) mRNA and proteins were significantly up-regulated in AFB1-treated dendritic cells.
HBsAg simulation increased proinflammatory cytokine production and invasion of HepG2.2.15 cells, while this process was inhibited by TLR2 silence.
this review highlights the contribution of TLR2 to host protection, immune evasion by Mycobacterium tuberculosis and immune regulation during chronic Mycobacterium tuberculosis infection
treatment with an antibody against Toll (zeige TLR4 ELISA Kits)-like receptor (TLR) 2 reversed the effect of L. paracasei on inducing negative regulators and inhibiting TNF-alpha (zeige TNF ELISA Kits) and IL-1beta (zeige IL1B ELISA Kits) productions.
Neonatal cells were more potent in the activation of ERK (zeige EPHB2 ELISA Kits) and Akt (zeige AKT1 ELISA Kits) through TLR2 and TLR4 (zeige TLR4 ELISA Kits) co-activation.
These results suggest that TLR2 and TLR4 (zeige TLR4 ELISA Kits) play cooperative roles in lung innate immune responses and bacterial dissemination, resulting in systemic inflammation during Klebsiella pneumoniae infection.
Toll-like receptor 2 (TLR2) controls random motility, while Toll-like receptor 7 (TLR7 (zeige TLR7 ELISA Kits)) regulates chemotaxis of microglial cells via distinct pathways. Furthermore, TLR7 (zeige TLR7 ELISA Kits) mRNA expression is down-regulated by TLR2 and TLR7 (zeige TLR7 ELISA Kits) activation.
Data suggest that continued toll-like receptor 2 activation contributes to the developing neuroinflammation and pathology and may be provide a strategy for limiting the progression of Alzheimer's disease.
results suggest that the TLR2-p38 (zeige CRK ELISA Kits)-CD86 (zeige CD86 ELISA Kits) signaling pathway plays a vital role in inflammation associated with burn injury
TLR2 and TLR4 (zeige TLR4 ELISA Kits) modulate the serotonin contractile motor response in mouse colon.
Isoflurane relieves zymosan-induced neutrophil inflammatory lung response by targeting NMDA glutamate receptor (zeige GRIN1 ELISA Kits) and Toll-like receptor 2 signaling pathway.
Results of RNA-sequencing demonstrated roles for TLR2 varied by cell type during T. gondii infection. Our findings facilitate understanding of the detailed relationship between TLR2 and T. gondii infection, and elucidate mechanisms underlying neurological changes during infection
TLR2 expression on B1a cells is not critical for their IgM-dependent atheroprotection.
Artificially applied c-kit (zeige KIT ELISA Kits)(+) cells interact with the target organ endothelium following ischemia reperfusion injury. This interaction seems to depend on TLR-MyD88 (zeige MYD88 ELISA Kits) signaling.
our results demonstrate that 5-HT (zeige DDC ELISA Kits) induces the invasion of commensal E. coli into gut (zeige GUSB ELISA Kits) submucosa by amplifying commensal bacteria-induced epithelial signaling (superoxide production and the inductions of NOX2 (zeige CYBB ELISA Kits) and TLR2/TLR4 (zeige TLR4 ELISA Kits)). The authors suggest that these changes may constitute the molecular basis for the pathogenesis of inflammatory bowel disease (IBD).
results suggest that polymorphisms in the TLR2 gene might not play a significant role in the BTB risk in Chinese Holstein cattle
Transcription levels of TLR2, TLR4 (zeige TLR4 ELISA Kits), and CD14 (zeige CD14 ELISA Kits) in Holstein cows with retained placenta significantly decreased between the first and the seventh day postpartum.
We structurally defined with 5'-RACE experiments three promoters (P1-3) controlling TLR2 expression in udder, liver and other tissues of cows suffering from E. coli mastitis.
TLR2 and TLR4 (zeige TLR4 ELISA Kits) mediate innate response against Cryptosporidium parvum in bovine intestinal epithelial cells.
positive correlation between lower neutrophil apoptosis and higher expression of TLR2 and TLR4 (zeige TLR4 ELISA Kits) with the formation of NETs and change in surface architecture.
TLR2, TLR1 (zeige TLR1 ELISA Kits), and TLR6 (zeige TLR6 ELISA Kits) haev roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides by epithelial and stromal cells of bovine endometrium
Data suggest that granulosa cells from dominant follicles express functional TLR2 and TLR4 (zeige TLR4 ELISA Kits); granulosa cells appear to participate in innate immunity by responding to bacterial lipopolysaccharides/lipopeptides via TLR2 and TLR4 (zeige TLR4 ELISA Kits) signaling pathways.
The expressions of host TLR2 and 4 genes were significantly higher in acidosis-resistant steers compared to those in acidosis-susceptible steers.
Whereas previous results regarding the TLR1 (zeige TLR1 ELISA Kits) gene were not corroborated, a risk haplotype was detected in TLR2; however, its low frequency indicates that this detected association should be interpreted with caution.
The identification of antibodies specific for bovine and ovine TLR2 will facilitate studies of the role of this important pattern recognition receptors in the initiation of immune responses to important pathogens.
TLR2, 3, 4, and 8 mRNA expression is strongly upregulated and correlates with the progression of atherosclerosis in the aorta. Fluvastatin significantly inhibited this progress and reduced inflammation via TLR downregulation.
Lipopolysaccharide upregulates the expression of rabbit TLR2 and 4 in the uterine body and horn, and the expression of TLR4 (zeige TLR4 ELISA Kits) in the ovary.
VB-201 may counter inflammation where TLR-2 and/or CD14 (zeige CD14 ELISA Kits) complicity is essential, and is therefore beneficial for the treatment of atherosclerosis.
we assume that reduced TLR2 expression may be responsible for the decreased phagocytizing capacity of circulating monocytes in the early post-traumatic phase
Toll-like receptor 2 signaling on intestinal epithelial cells may enhance intestinal barrier function and prevent deoxynivalenol-induced barrier dysfunction of epithelial cells.
These results suggest that porcine circovirus 2 induces IL-8 (zeige IL8 ELISA Kits) secretion via the TLR2/MyD88 (zeige MYD88 ELISA Kits)/NF-kappaB (zeige NFKB1 ELISA Kits) signalling pathway.
At 14 days after autotransplantation of a pig kidney, mRNA expression for TLR2 is increased.
These data demonstrated that TLR2, TLR3 (zeige TLR3 ELISA Kits) and TLR9 (zeige TLR9 ELISA Kits) contribute to NF-kappaB (zeige NFKB1 ELISA Kits) activation in response to porcine epidemic diarrhea virus infection, but not RIG-I (zeige DDX58 ELISA Kits).
Data suggest TLR2, TLR4 (zeige TLR4 ELISA Kits), and calcium signaling in enterocytes play principal roles in mucosal immunity against enterotoxigenic Escherichia coli; probiotic Lactobacillus delbrueckii and its extracellular polysaccharides appear to stimulate TLR2/TLR4 (zeige TLR4 ELISA Kits).
TLR2 is required for the suppression of TLR4 (zeige TLR4 ELISA Kits) signaling activation.
The role of TLR2, TLR4 (zeige TLR4 ELISA Kits) and RP105 (zeige CD180 ELISA Kits)/MD1 (zeige LY86 ELISA Kits) in the immunoregulatory effect of acidic exopolysaccharides from Lactobacillus plantarum N14 (zeige CLPTM1 ELISA Kits), is reported.
Single nucleotide polymorphisms in TLR2 is associated with immune response to gram-negative bacterial infections.
The dramatic reduction in p38 MAPK (zeige MAPK14 ELISA Kits) phosphorylation by TLR-2 stimulation in aortic valve interstitial cells excludes a role for this receptor type in mediating angiotensin II or peroxynitrite effects.
expression of TLR4 (zeige TLR4 ELISA Kits) and TLR2 in normal and LPS (zeige IRF6 ELISA Kits)-treated horses
Because factors other than mastitis can affect SCC (zeige CYP11A1 ELISA Kits) and our sample sizes were limited, additional studies are needed to corroborate an association between TLR2 genotype and SCC (zeige CYP11A1 ELISA Kits) or mastitis in goats.
Over-expression of TLR2 decreases radical damage to host cells through low-level production of NO and MDA and promotes the clearance of invasive bacteria by up-regulating lysozyme (zeige LYZ ELISA Kits) secretion and filtration of inflammatory cells to the infected site.
TLR2 of M. fuscata has undergone purifying selection while the membrane-proximal part of the extracellular domain of M. mulatta TLR2 exhibits higher rates of non-synonymous substitutions, indicating a trace of Darwinian positive selection
The results indicate that microglia and astrocytes respond to B (zeige TDO2 ELISA Kits). burgdorferi through TLR1 (zeige TLR1 ELISA Kits)/2 and TLR5 (zeige TLR5 ELISA Kits).
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
toll/interleukin 1 receptor-like 4
, toll/interleukin-1 receptor-like protein 4
, toll-like receptor 2 variant 1
, toll-like receptor 2 variant 2
, toll-like receptor 2 type-2
, toll-like receptor 2 type2
, Toll-like receptor 2-like protein