anti-Human TLR1 Antikörper für Western Blotting

Recommended TLR1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 1 (TLR1) Antikörper
  • CD281
  • TIL
  • TIL. LPRS5
  • rsc786
  • toll like receptor 1
  • toll-like receptor 1
  • TLR1
  • Tlr1
Reaktivität
Maus, Ratte (Rattus), Human
178
90
41
1
Wirt
Kaninchen
140
47
17
1
Klonalität
Polyklonal
Konjugat
Dieser TLR1 Antikörper ist unkonjugiert
18
17
16
5
5
3
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
131
78
74
52
37
14
14
13
13
12
11
7
6
3
2
Optionen
Hersteller
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Bilder

Produktnummer ABIN3023655
$ 393.25
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
19.802324 ABIN5693146 ELISA FACS ICC IHC WB Rabbit AA 350-404 Anmelden zum Anzeigen Polyclonal 0
17.5 ABIN736373 FACS IF (p) IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 1
12.760654 ABIN5622891 ELISA WB Goat IgG Anmelden zum Anzeigen Polyclonal 0
12.760654 ABIN2153285 ELISA WB Goat IgG Anmelden zum Anzeigen Polyclonal 0
12.760654 ABIN6149211 WB Rabbit Anmelden zum Anzeigen Polyclonal 0
10.802324 ABIN6002117 IF/ICC IHC IP WB Mouse AA 114-339 Anmelden zum Anzeigen 0
10.802324 ABIN2427609 IHC ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
10.802324 ABIN5662353 IHC WB Mouse AA 114-339 Anmelden zum Anzeigen 0
9.302324 ABIN2479707 IHC (fro) WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 3
9.302324 ABIN550246 IHC (fro) WB Rabbit Anmelden zum Anzeigen Polyclonal 3
7.8023243 ABIN6265596 ELISA IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
7.8023243 ABIN3197579 IC IF WB Rabbit Anmelden zum Anzeigen Polyclonal 0
7.8023243 ABIN1875107 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
7.8023243 ABIN1860768 ICC IHC WB Rabbit IgG AA 605-785 Anmelden zum Anzeigen Polyclonal 0
7.8023243 ABIN1175315 ICC IHC WB Rabbit IgG AA 114-339 Anmelden zum Anzeigen Polyclonal 0
7.8023243 ABIN2988994 IF/ICC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
7.8023243 ABIN1031619 IHC ELISA WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 0
7.8023243 ABIN1031127 ICC ELISA WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 0
7.8023243 ABIN3029159 IHC ELISA WB Rabbit Ig Fraction AA 764-795 Anmelden zum Anzeigen Polyclonal 0
7.8023243 ABIN6006176 IF/ICC WB Rabbit IgG full length Anmelden zum Anzeigen Polyclonal 0

General

Antigen Toll-Like Receptor 1 (TLR1) Antikörper
Reaktivität Maus, Ratte (Rattus), Human
(178), (90), (41), (1)
Wirt Kaninchen
(140), (47), (17), (1)
Klonalität
Polyklonal
Konjugat Dieser TLR1 Antikörper ist unkonjugiert
(18), (17), (16), (5), (5), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(131), (78), (74), (52), (37), (14), (14), (13), (13), (12), (11), (7), (6), (3), (2)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR1 Antikörper

Target Details TLR1 Anwendungsinformationen Handhabung Bilder
Reinigung Affinity purification
Immunogen Recombinant protein of human TLR1
Isotyp IgG
Plasmids, Primers & others

Target Details TLR1

Produktdetails anti-TLR1 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung TLR1 (TLR1 Antibody Abstract)
Hintergrund Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-kappaB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 AAs known as the TIR domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor), MAL/TIRAP (MyD88-adaptor-like/TIR-associated protein), TRIF (Toll-receptor-associated activator of interferon), and TRAM (Toll-receptor-associated molecule). This association leads to the recruitment and activation of IRAK1 and IRAK4, which form a complex with TRAF6 to activate TAK1 and IKK. Activation of IKK leads to the degradation of IkappaB that normally maintains NF-kappaB inactivity by sequestering it in the cytoplasm. Toll-like receptor expression is highest in peripheral blood leukocytes, monocytes, macrophages, though TLR1 expression may be less restricted than other family members. TLR1 associates with TLR2 to cooperatively mediate immune responses to bacterial lipoproteins and lead to NF-kappaB activation. TLR1 shows highest homology to TLR6, which shares 69 % sequence identity.
Synonyms: TLR1, CD281, DKFZp547I0610, DKFZp564I0682, KIAA0012, MGC104956, MGC126311, MGC126312, TIL, rsc786
Gen-ID 7096
UniProt Q15399
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR1 Antikörper Target Details TLR1 Handhabung Bilder zurück nach oben
Applikations-hinweise Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR1 Antikörper Target Details TLR1 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze / thaw cycles
Lagerung -20 °C/-80 °C

Bilder

Produktdetails anti-TLR1 Antikörper Target Details TLR1 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Toll-Like Receptor 1 (TLR1) antibody (ABIN3023655) Western blot analysis of extracts of various cell lines, using TLR1 antibody.
Immunofluorescence (IF) image for anti-Toll-Like Receptor 1 (TLR1) antibody (ABIN3023655) Immunofluorescence analysis of HeLa cell using TLR1 antibody. Blue: DAPI for nuclear ...
Western Blotting (WB) image for anti-Toll-Like Receptor 1 (TLR1) antibody (ABIN3023655) Western blot analysis of extracts of various cell lines, using TLR1 antibody.
Immunofluorescence (IF) image for anti-Toll-Like Receptor 1 (TLR1) antibody (ABIN3023655) Immunofluorescence analysis of HeLa cells using TLR1 antibody.