anti-Human TLR1 Antikörper für Immunohistochemistry

Recommended TLR1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 1 (TLR1) Antikörper
  • CD281
  • TIL
  • TIL. LPRS5
  • rsc786
  • toll like receptor 1
  • toll-like receptor 1
  • TLR1
  • Tlr1
Reaktivität
Maus, Ratte (Rattus), Human
181
92
42
1
Wirt
Kaninchen
146
45
17
1
Klonalität
Polyklonal
Konjugat
Dieser TLR1 Antikörper ist unkonjugiert
18
17
16
5
5
3
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
137
77
76
55
38
14
14
13
13
12
11
7
6
3
2
Optionen
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Bilder

Produktnummer ABIN3023655
$ 393.25
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
21.863953 ABIN5693146 ELISA FACS ICC IHC WB Rabbit AA 350-404 Anmelden zum Anzeigen Polyclonal 0
18.560627 ABIN252519 FACS IHC IHC (p) WB Rabbit Anmelden zum Anzeigen Polyclonal 11
18.245823 ABIN3181539 IHC Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
18.245823 ABIN3181537 IHC Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
12.863952 ABIN2427609 IHC ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
10 ABIN1875107 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
10 ABIN6002117 IF/ICC IHC IP WB Mouse AA 114-339 Anmelden zum Anzeigen 0
10 ABIN5662353 IHC WB Mouse AA 114-339 Anmelden zum Anzeigen 0
9.863952 ABIN959418 FACS IHC IHC (p) WB Rabbit IgG AA 400-450 Anmelden zum Anzeigen Polyclonal 0
9.863952 ABIN6265596 ELISA IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
9.863952 ABIN213996 ICC IHC IHC (p) WB Rabbit IgG Internal Region Anmelden zum Anzeigen Polyclonal 0
9.863952 ABIN214527 IHC IHC (p) WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 0
9.863952 ABIN1031619 IHC ELISA WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 0
9.863952 ABIN3029159 IHC ELISA WB Rabbit Ig Fraction AA 764-795 Anmelden zum Anzeigen Polyclonal 0
7 ABIN1175315 ICC IHC WB Rabbit IgG AA 114-339 Anmelden zum Anzeigen Polyclonal 0
7 ABIN1860768 ICC IHC WB Rabbit IgG AA 605-785 Anmelden zum Anzeigen Polyclonal 0
7 ABIN2903124 IF/ICC IHC IP WB Rabbit AA 114-339 Anmelden zum Anzeigen Polyclonal 0
7 ABIN2903125 IF/ICC IHC IP WB Rabbit AA 605-785 Anmelden zum Anzeigen Polyclonal 0
5.5 ABIN1003315 IHC ELISA WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 4
1 ABIN2888061 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0

General

Antigen Toll-Like Receptor 1 (TLR1) Antikörper
Reaktivität Maus, Ratte (Rattus), Human
(181), (92), (42), (1)
Wirt Kaninchen
(146), (45), (17), (1)
Klonalität
Polyklonal
Konjugat Dieser TLR1 Antikörper ist unkonjugiert
(18), (17), (16), (5), (5), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(137), (77), (76), (55), (38), (14), (14), (13), (13), (12), (11), (7), (6), (3), (2)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR1 Antikörper

Target Details TLR1 Anwendungsinformationen Handhabung Bilder
Reinigung Affinity purification
Immunogen Recombinant protein of human TLR1
Isotyp IgG
Plasmids, Primers & others

Target Details TLR1

Produktdetails anti-TLR1 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung TLR1 (TLR1 Antibody Abstract)
Hintergrund Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-kappaB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 AAs known as the TIR domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor), MAL/TIRAP (MyD88-adaptor-like/TIR-associated protein), TRIF (Toll-receptor-associated activator of interferon), and TRAM (Toll-receptor-associated molecule). This association leads to the recruitment and activation of IRAK1 and IRAK4, which form a complex with TRAF6 to activate TAK1 and IKK. Activation of IKK leads to the degradation of IkappaB that normally maintains NF-kappaB inactivity by sequestering it in the cytoplasm. Toll-like receptor expression is highest in peripheral blood leukocytes, monocytes, macrophages, though TLR1 expression may be less restricted than other family members. TLR1 associates with TLR2 to cooperatively mediate immune responses to bacterial lipoproteins and lead to NF-kappaB activation. TLR1 shows highest homology to TLR6, which shares 69 % sequence identity.
Synonyms: TLR1, CD281, DKFZp547I0610, DKFZp564I0682, KIAA0012, MGC104956, MGC126311, MGC126312, TIL, rsc786
Gen-ID 7096
UniProt Q15399
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR1 Antikörper Target Details TLR1 Handhabung Bilder zurück nach oben
Applikations-hinweise Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR1 Antikörper Target Details TLR1 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze / thaw cycles
Lagerung -20 °C/-80 °C

Bilder

Produktdetails anti-TLR1 Antikörper Target Details TLR1 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Toll-Like Receptor 1 (TLR1) antibody (ABIN3023655) Western blot analysis of extracts of various cell lines, using TLR1 antibody.
Immunofluorescence (IF) image for anti-Toll-Like Receptor 1 (TLR1) antibody (ABIN3023655) Immunofluorescence analysis of HeLa cell using TLR1 antibody. Blue: DAPI for nuclear ...
Western Blotting (WB) image for anti-Toll-Like Receptor 1 (TLR1) antibody (ABIN3023655) Western blot analysis of extracts of various cell lines, using TLR1 antibody.
Immunofluorescence (IF) image for anti-Toll-Like Receptor 1 (TLR1) antibody (ABIN3023655) Immunofluorescence analysis of HeLa cells using TLR1 antibody.