anti-Ratte (Rattus) TIRAP Antikörper für Enzyme Immunoassay

Recommended TIRAP Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) Antikörper
  • mal
  • wyatt
  • BACTS1
  • Mal
  • MyD88-2
  • AA407980
  • C130027E04Rik
  • Tlr4ap
  • Wyatt
  • toll-interleukin 1 receptor (TIR) domain containing adaptor protein
  • TIR domain containing adaptor protein
  • toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog
  • toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
  • tirap
  • TIRAP
  • tirap.L
  • Tirap
Epitop
C-Term
29
21
15
5
5
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
147
69
38
2
2
2
1
1
1
1
Wirt
Kaninchen
112
31
5
5
Klonalität
Polyklonal
Konjugat
Dieser TIRAP Antikörper ist unkonjugiert
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
109
60
51
28
26
7
3
2
2
1
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN5555322
$ 474.10
Zzgl. Versandkosten $45.00

General

Antigen Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) Antikörper
Epitop C-Term
(29), (21), (15), (5), (5), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(147), (69), (38), (2), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(112), (31), (5), (5)
Klonalität
Polyklonal
Konjugat Dieser TIRAP Antikörper ist unkonjugiert
(4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(109), (60), (51), (28), (26), (7), (3), (2), (2), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TIRAP Antikörper

Target Details TIRAP Anwendungsinformationen Handhabung Bilder
Spezifität This antibody detects TIRAP at C-term.
Kreuzreaktivität (Details) Species reactivity (tested):Human, mouse, rat
Reinigung Peptide affinity chromatography
Immunogen TIRAP antibody was raised against a peptide corresponding to 15 amino acids near the C- terminus of mouse TIRAP.
Isotyp IgG
Plasmids, Primers & others

Target Details TIRAP

Produktdetails anti-TIRAP Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung TIRAP (TIRAP Antibody Abstract)
Hintergrund Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as TIRAP and MyD88 to activate various kinases and transcription factors (4,5). In TIRAP-deficient mice, TLR signaling in response to TLR2 ligands (using either TLR1 and TLR6 as co-receptors) is totally abolished, suggesting that MyD88 and TIRAP work together and are both required for TLR2 signaling (6). Furthermore, these mice are also resistant to the toxic effects of LPS and show defects in NF-?B and MAP kinase activation, suggesting that TIRAP is also involed in TLR4 signaling (6,7).Synonyms: Adaptor protein Wyatt, MAL, MyD88 adapter-like protein, TIR domain-containing adapter protein, Toll/interleukin-1 receptor domain-containing adapter protein
Gen-ID 114609
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TIRAP Antikörper Target Details TIRAP Handhabung Bilder zurück nach oben
Applikations-hinweise ELISA. Western blot: 0.5 to 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TIRAP Antikörper Target Details TIRAP Anwendungsinformationen Bilder zurück nach oben
Buffer PBS containing 0.02 % sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.