anti-Maus TAB1 Antikörper für Western Blotting
Recommended TAB1 Antibody (geliefert von: Anmelden zum Anzeigen )
- Antigen
-
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) Antikörper
Synonyme für dieses Antigen anzeigen- 3'-Tab1
- MAP3K7IP1
- 2310012M03Rik
- Map3k7ip1
- b2b449Clo
- TGF-beta activated kinase 1 (MAP3K7) binding protein 1
- TGF-beta activated kinase 1/MAP3K7 binding protein 1
- TAB1
- Tab1
- Epitop
-
N-Term
Alternativen - Reaktivität
-
Hund, Meerschweinchen, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
Alternativen - Wirt
-
Kaninchen
Alternativen - Klonalität
- Konjugat
-
Dieser TAB1 Antikörper ist unkonjugiert
Alternativen - Applikation
-
Western Blotting (WB)
Alternativen - Optionen
- Hersteller
- Anmelden zum Anzeigen
- Hersteller Produkt- Nr.
- Anmelden zum Anzeigen
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Bilder
Produktnummer ABIN2785275
$ 289.00
Zzgl. Versandkosten $45.00
Zzgl. Versandkosten $45.00
| Relevance Score | ABIN | Application | Konjugat | Host | Isotype | Epitope | Hersteller | Clonality | References | Details |
|---|---|---|---|---|---|---|---|---|---|---|
| 3.0748372 | ABIN3042547 | WB | Rabbit | IgG | AA 304-321, C-Term | Anmelden zum Anzeigen | Polyclonal | 0 | ||
| 3.0748372 | ABIN439365 | IP WB | Rabbit | AA 435-485 | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 3.0748372 | ABIN2737641 | IF IHC WB | Rabbit | IgG | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 3.0748372 | ABIN634348 | WB | Rabbit | N-Term | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 3.0748372 | ABIN2968031 | IF/ICC WB | Rabbit | IgG | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 3.0748372 | ABIN3198337 | WB | Rabbit | Anmelden zum Anzeigen | Polyclonal | 0 | ||||
| 3.0748372 | ABIN5923309 | WB | Rabbit | pSer438 | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 3.0748372 | ABIN6006154 | WB | Rabbit | IgG | full length | Anmelden zum Anzeigen | Polyclonal | 0 | ||
| 3.0748372 | ABIN1031115 | ICC ELISA WB | Rabbit | Middle Region | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 3.0748372 | ABIN3029117 | WB | Rabbit | IgG | C-Term | Anmelden zum Anzeigen | Polyclonal | 0 | ||
| 3.0748372 | ABIN2423759 | IHC ELISA WB | Rabbit | IgG | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 1 | ABIN469577 | WB | Rabbit | N-Term | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 1 | ABIN214510 | ICC IHC IHC (p) WB | Rabbit | IgG | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 1 | ABIN303281 | IF IHC (p) WB | Rabbit | Center | Anmelden zum Anzeigen | Polyclonal | 1 | |||
| 1 | ABIN223361 | WB | Rabbit | IgG | C-Term | Anmelden zum Anzeigen | Polyclonal | 0 | ||
| 1 | ABIN333172 | ELISA WB | Mouse | IgG2a, kappa | Anmelden zum Anzeigen | 0 | ||||
| 1 | ABIN6269553 | ELISA IHC WB | Rabbit | IgG | pTyr481 | Anmelden zum Anzeigen | Polyclonal | 0 | ||
| 1 | ABIN6271814 | ELISA WB | Rabbit | IgG | pSer438 | Anmelden zum Anzeigen | Polyclonal | 0 | ||
| 1 | ABIN1739871 | ICC IHC (p) WB | Rabbit | IgG | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 1 | ABIN2628928 | WB | Rabbit | IgG | AA 304-321 | Anmelden zum Anzeigen | Polyclonal | 0 |
General |
|
|---|---|
| Antigen | TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) Antikörper |
| Epitop | N-Term Alternativen |
| Reaktivität | Hund, Meerschweinchen, Human, Maus, Schwein, Kaninchen, Ratte (Rattus) Alternativen |
| Wirt | Kaninchen Alternativen |
| Klonalität | |
| Konjugat | Dieser TAB1 Antikörper ist unkonjugiert Alternativen |
| Applikation |
Western Blotting (WB)
Alternativen
|
|
1 Publikation vorhanden |
| Hersteller | Anmelden zum Anzeigen |
Produktdetails anti-TAB1 AntikörperTarget Details TAB1 Anwendungsinformationen Handhabung Referenzen für anti-TAB1 Antikörper (ABIN2785275) Bilder |
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| Blocking Peptide | Zu diesem Produkt passt das Blocking Peptide ABIN979778. |
| Sequenz | MAAQRRSLLQ SEQQPSWTDD LPLCHLSGVG SASNRSYSAD GKGTESHPPE |
| Homologie | Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100% |
| Produktmerkmale | This is a rabbit polyclonal antibody against MAP3K7IP1. It was validated on Western Blot using a cell lysate as a positive control. |
| Reinigung | Affinity Purified |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K7IP1 |
| Plasmids, Primers & others | |
Target Details TAB1Produktdetails anti-TAB1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TAB1 Antikörper (ABIN2785275) Bilder zurück nach oben |
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| Antigen | |
| Andere Bezeichnung | MAP3K7IP1 (TAB1 Antibody Abstract) |
| Hintergrund |
The specific function of the protein remains unknown.The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported. Alias Symbols: 3'-Tab1, MGC57664, TAB1, MAP3K7IP1 Protein Interaction Partner: MAGED1, BAG2, MAP3K7, TIRAP, MDM2, SLMAP, NPM1, BIRC3, TRIP6, PPP2R1A, PPP2CB, GRB2, FN1, CDK5RAP3, TAB2, CORO1A, WTAP, MAPK8IP1, UBC, MAPK14, BST2, MAPK12, HSP90AA1, NOTCH1, IKBKB, GRK5, EGFR, STE11, BIRC7, NAIP, XIAP, OGT, TAB3, NR2C2, ARRB2, ARAP1, ACA Protein Size: 462 |
| Molekulargewicht | 50 kDa |
| Gen-ID | 10454 |
| NCBI Accession | NM_153497, NP_705717 |
| UniProt | Q8IZW2 |
| Pathways | TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades |
AnwendungsinformationenProduktdetails anti-TAB1 Antikörper Target Details TAB1 Handhabung Referenzen für anti-TAB1 Antikörper (ABIN2785275) Bilder zurück nach oben |
|
| Applikations-hinweise | Optimal working dilutions should be determined experimentally by the investigator. |
| Kommentare |
Antigen size: 462 AA |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails anti-TAB1 Antikörper Target Details TAB1 Anwendungsinformationen Referenzen für anti-TAB1 Antikörper (ABIN2785275) Bilder zurück nach oben |
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| Format | Liquid |
| Konzentration | Lot specific |
| Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
| Konservierungs-mittel | Sodium azide |
| Vorsichtsmaßnahmen | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Handhabung | Avoid repeated freeze-thaw cycles. |
| Lagerung | -20 °C |
| Informationen zur Lagerung | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Referenzen für anti-TAB1 Antikörper (ABIN2785275)Produktdetails anti-TAB1 Antikörper Target Details TAB1 Anwendungsinformationen Handhabung Bilder zurück nach oben |
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| Allgemeine Veröffentlichungen |
Neil, Schiemann: "Altered TAB1:I kappaB kinase interaction promotes transforming growth factor beta-mediated nuclear factor-kappaB activation during breast cancer progression." in: Cancer research, Vol. 68, Issue 5, pp. 1462-70, 2008 |
BilderProduktdetails anti-TAB1 Antikörper Target Details TAB1 Anwendungsinformationen Handhabung Referenzen für anti-TAB1 Antikörper (ABIN2785275) zurück nach oben |
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| Bilder des Herstellers |
WB Suggested Anti-MAP3K7IP1 Antibody Titration: 0.2-1 ug/mlELISA Titer:... |
