anti-Human TAB1 Antikörper für Enzyme Immunoassay

Recommended TAB1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) Antikörper
  • 3'-Tab1
  • MAP3K7IP1
  • 2310012M03Rik
  • Map3k7ip1
  • b2b449Clo
  • TGF-beta activated kinase 1 (MAP3K7) binding protein 1
  • TGF-beta activated kinase 1/MAP3K7 binding protein 1
  • TAB1
  • Tab1
Epitop
Ser438
18
11
10
10
9
9
7
6
6
5
5
3
2
2
2
2
2
2
1
1
1
1
1
1
1
Reaktivität
Human
171
70
51
8
6
5
4
3
3
2
1
1
1
1
Wirt
Kaninchen
144
25
2
Klonalität
Polyklonal
Konjugat
Dieser TAB1 Antikörper ist unkonjugiert
8
8
7
6
6
6
2
2
2
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
130
78
21
18
16
15
12
9
9
3
2
2
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN401658
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
4 ABIN453175 EIA WB Rabbit Ser423 Anmelden zum Anzeigen Polyclonal 2
1 ABIN5555289 EIA IF WB Rabbit IgG Center Anmelden zum Anzeigen Polyclonal 0

General

Antigen TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) Antikörper
Epitop Ser438
(18), (11), (10), (10), (9), (9), (7), (6), (6), (5), (5), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(171), (70), (51), (8), (6), (5), (4), (3), (3), (2), (1), (1), (1), (1)
Wirt Kaninchen
(144), (25), (2)
Klonalität
Polyklonal
Konjugat Dieser TAB1 Antikörper ist unkonjugiert
(8), (8), (7), (6), (6), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Western Blotting (WB)
(130), (78), (21), (18), (16), (15), (12), (9), (9), (3), (2), (2), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TAB1 Antikörper

Target Details TAB1 Anwendungsinformationen Handhabung Referenzen für anti-TAB1 Antikörper (ABIN401658) Bilder
Spezifität AP09519PU-N recognizes MAP3K7IP1 pSer438.
Kreuzreaktivität (Details) Species reactivity (tested):Human.
Reinigung Protein A Chromatography followed by peptide Affinity purification.
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the amino acid residues surrounding Ser438 of human MAP3K7IP1.
Plasmids, Primers & others

Target Details TAB1

Produktdetails anti-TAB1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TAB1 Antikörper (ABIN401658) Bilder zurück nach oben
Antigen
Andere Bezeichnung TAB1 / MAP3K7IP1 (TAB1 Antibody Abstract)
Hintergrund MAP3K7IP1 was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli.Synonyms: Mitogen-activated protein kinase kinase kinase 7-interacting protein 1, TAK1-binding protein 1, TGF-beta-activated kinase 1-binding protein 1
Molekulargewicht 54644 Da
Gen-ID 10454
NCBI Accession NP_006107
UniProt Q15750
Pathways TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TAB1 Antikörper Target Details TAB1 Handhabung Referenzen für anti-TAB1 Antikörper (ABIN401658) Bilder zurück nach oben
Applikations-hinweise ELISA: 1/1,000Western blot: 1/100approx. 500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TAB1 Antikörper Target Details TAB1 Anwendungsinformationen Referenzen für anti-TAB1 Antikörper (ABIN401658) Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen für anti-TAB1 Antikörper (ABIN401658)

Produktdetails anti-TAB1 Antikörper Target Details TAB1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Yamaguchi, Nagai, Ninomiya-Tsuji, Nishita, Tamai, Irie, Ueno, Nishida, Shibuya, Matsumoto: "XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway." in: The EMBO journal, Vol. 18, Issue 1, pp. 179-87, 1999

Arch, Gedrich, Thompson: "Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death." in: Genes & development, Vol. 12, Issue 18, pp. 2821-30, 1998

Bilder

Produktdetails anti-TAB1 Antikörper Target Details TAB1 Anwendungsinformationen Handhabung Referenzen für anti-TAB1 Antikörper (ABIN401658) zurück nach oben
Bilder des Herstellers
 image for anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (Ser438) antibody (ABIN401658) anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (Ser438) antibody