anti-Ratte (Rattus) Interferon Regulatory Factor 3 Antikörper für ELISA

Recommended Interferon Regulatory Factor 3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Interferon Regulatory Factor 3 (IRF3) Antikörper
  • irf3
  • IRF3
  • C920001K05Rik
  • IRF-3
  • interferon regulatory factor 3
  • interferon regulatory factor 7
  • irf3
  • IRF3
  • irf-3
  • Irf3
  • IRF7
Epitop
pSer385
27
21
19
19
19
16
15
15
12
11
9
5
4
4
4
4
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Ratte (Rattus)
290
123
71
7
6
6
3
2
2
1
1
1
1
Wirt
Kaninchen
257
63
3
Klonalität
Polyklonal
Konjugat
Unkonjugiert
7
6
6
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Applikation
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
267
128
102
76
51
40
28
27
25
14
14
8
4
3
3
2
2
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN6255286
$ 390.77
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1532452 IHC ELISA WB Rabbit IgG AA 362-411 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1531435 ELISA WB Rabbit IgG AA 362-411, pSer396 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2888732 ELISA IHC WB Rabbit IgG AA 362-411 Anmelden zum Anzeigen Polyclonal 0
1 ABIN3185228 ELISA IHC WB Rabbit IgG Ser608 Anmelden zum Anzeigen Polyclonal 0
1 ABIN6262652 ELISA ICC IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN6270186 ELISA IHC WB Rabbit IgG pSer15 Anmelden zum Anzeigen Polyclonal 0
1 ABIN4327552 ELISA ICC IF WB Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN5956956 ELISA IHC (p) WB Rabbit IgG Ser396 Anmelden zum Anzeigen Polyclonal 0
1 ABIN3182223 ELISA WB Rabbit IgG pSer396 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2883948 ELISA WB Rabbit IgG pSer396 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1452633 ELISA WB Rabbit IgG pSer396 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1577321 IHC ELISA WB Rabbit IgG Ser396 Anmelden zum Anzeigen Polyclonal 0
1 ABIN5697970 ELISA FACS IF IHC IP WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN6104997 ELISA IHC WB Rabbit IgG Ser396 Anmelden zum Anzeigen Polyclonal 0
1 ABIN6103426 ELISA WB Rabbit IgG pSer396 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2428297 IHC ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN2421745 IHC ELISA Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN5869183 ELISA FACS IF/ICC IHC IP WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0

General

Antigen Interferon Regulatory Factor 3 (IRF3) Antikörper
Epitop pSer385
(27), (21), (19), (19), (19), (16), (15), (15), (12), (11), (9), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Ratte (Rattus)
(290), (123), (71), (7), (6), (6), (3), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(257), (63), (3)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(7), (6), (6), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Applikation ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(267), (128), (102), (76), (51), (40), (28), (27), (25), (14), (14), (8), (4), (3), (3), (2), (2), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Spezifität Phospho-IRF-3 (Ser385) Antibody detects endogenous levels of IRF-3 only when phosphorylated at Serine 385
Kreuzreaktivität Human, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Immunogen A synthesized peptide derived from human IRF-3 around the phosphorylation site of Serine 385
Isotyp IgG

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung IRF-3 (IRF3 Antibody Abstract)
Hintergrund

Description: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Acts as a more potent activator of the IFN-beta (IFNB) gene than the IFN-alpha (IFNA) gene and plays a critical role in both the early and late phases of the IFNA/B gene induction. Found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA (dsRNA), or toll-like receptor (TLR) signaling, is phosphorylated by IKBKE and TBK1 kinases. This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes. Can activate distinct gene expression programs in macrophages and can induce significant apoptosis in primary macrophages.

Gene: IRF3

Molekulargewicht 57kDa
Gen-ID 3661
UniProt Q14653
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikations-hinweise WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Interferon Regulatory Factor 3 (IRF3) (pSer385) antibody (ABIN6255286) ABIN6267647 staining HT29 by IF/ICC. The sample were fixed with PFA and permeabilized...
Western Blotting (WB) image for anti-Interferon Regulatory Factor 3 (IRF3) (pSer385) antibody (ABIN6255286) Western blot analysis of IRF-3 phosphorylation expression in Insulin treated HT29 who...
Immunohistochemistry (IHC) image for anti-Interferon Regulatory Factor 3 (IRF3) (pSer385) antibody (ABIN6255286) ABIN6267647 at 1/100 staining Rat brain tissue by IHC-P. The sample was formaldehyde ...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Interferon Regulatory Factor 3 (IRF3) (pSer385) antibody (ABIN6255286) ABIN6267647 staining HeLa cells by ICC/IF. Cells were fixed with PFA and permeabilize...