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General |
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Antigen | Interferon Regulatory Factor 3 (IRF3) Antikörper |
Reaktivität | Hund, Human Alternativen |
Wirt | Kaninchen Alternativen |
Klonalität | |
Konjugat | Unkonjugiert Alternativen |
Applikation |
ELISA, Western Blotting (WB)
Alternativen
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Hersteller | Anmelden zum Anzeigen |
ProduktdetailsAntigendetails Anwendungsinformationen Handhabung Bilder |
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Reinigung | Antibody is purified by peptide affinity chromatography method. |
Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IRF3. |
AntigendetailsProduktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben |
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Antigen | |
Andere Bezeichnung | IRF3 (IRF3 Antibody Abstract) |
Hintergrund | IRF3 is interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. |
Molekulargewicht | 47 kDa |
Gen-ID | 3661 |
NCBI Accession | NP_001562 |
UniProt | Q14653 |
Pathways | TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades |
AnwendungsinformationenProduktdetails Antigendetails Handhabung Bilder zurück nach oben |
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Applikations-hinweise | IRF3 antibody can be used for detection of IRF3 by ELISA at 1:312500. IRF3 antibody can be used for detection of IRF3 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben |
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Format | Lyophilized |
Rekonstitution | Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL. |
Konzentration | 1 mg/mL |
Buffer | Antibody is lyophilized in PBS buffer with 2 % sucrose. |
Handhabung | As with any antibody avoid repeat freeze-thaw cycles. |
Lagerung | 4 °C/-20 °C |
Informationen zur Lagerung | For short periods of storage (days) store at 4 °C. For longer periods of storage, store IRF3 antibody at -20 °C. |
BilderProduktdetails Antigendetails Anwendungsinformationen Handhabung zurück nach oben |
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Bilder des Herstellers |