anti-Primate CD14 Antikörper für Enzyme Immunoassay

Recommended CD14 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
CD14 Molecule (CD14) Antikörper
  • CD14 molecule
  • CD14 antigen
  • CD14
  • Cd14
Reaktivität
Human, Primate
941
122
102
90
90
73
65
64
62
61
59
49
44
41
33
27
21
13
10
9
9
9
4
3
3
1
1
Wirt
Maus
859
141
48
24
3
Klonalität
Monoklonal
Konjugat
Dieser CD14 Antikörper ist unkonjugiert
103
98
73
67
29
16
16
13
13
13
10
9
8
8
8
7
7
7
7
7
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Functional Studies (Func), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
828
269
213
204
184
141
68
52
47
41
26
14
13
13
11
8
6
4
3
3
3
3
3
3
2
2
2
1
1
1
1
Hersteller
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Produktnummer ABIN126002
$ 253.00
Zzgl. Versandkosten $45.00

General

Antigen CD14 Molecule (CD14) Antikörper
Reaktivität Human, Primate
(941), (122), (102), (90), (90), (73), (65), (64), (62), (61), (59), (49), (44), (41), (33), (27), (21), (13), (10), (9), (9), (9), (4), (3), (3), (1), (1)
Wirt Maus
(859), (141), (48), (24), (3)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CD14 Antikörper ist unkonjugiert
(103), (98), (73), (67), (29), (16), (16), (13), (13), (13), (10), (9), (8), (8), (8), (7), (7), (7), (7), (7), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Functional Studies (Func), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
(828), (269), (213), (204), (184), (141), (68), (52), (47), (41), (26), (14), (13), (13), (11), (8), (6), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CD14 Antikörper

Target Details CD14 Anwendungsinformationen Handhabung Bilder
Reinigung Protein A Chromatography
Immunogen A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria
Klon MEM-18
Isotyp IgG1
Plasmids, Primers & others

Target Details CD14

Produktdetails anti-CD14 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung CD14 (CD14 Antibody Abstract)
Hintergrund CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor, it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein
UniProt P08571
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-CD14 Antikörper Target Details CD14 Handhabung Bilder zurück nach oben
Applikations-hinweise Flow cytometry. Immunoprecipitation. Western blotting (non-denaturing conditions). ELISA: antibody MEM-18 has been tested as the detection antibody in a sandwich ELISA for analysis of human CD14 in combination with clone B-A8 (ABIN120555). Functional application: completely blocks binding of fluorescein (FITC) labeled bacterial LPS to the monocyte surface and it also blocks the binding of CD14 to the extracellular TLR2 domain.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CD14 Antikörper Target Details CD14 Anwendungsinformationen Bilder zurück nach oben
Konzentration 1.0 mg/mL
Buffer Azide Free Phosphate Buffered Saline (PBS), pH ~7.4, 0.2 μm filter sterilized. Endotoxin level is less than 10 EU/mg of the protein, as determined by the LAL test.
Konservierungs-mittel Azide free
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
Haltbarkeit 12 months