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anti-Mouse (Murine) Glutathione Peroxidase 1 Antikörper:
anti-Human Glutathione Peroxidase 1 Antikörper:
anti-Rat (Rattus) Glutathione Peroxidase 1 Antikörper:
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Human Polyclonal Glutathione Peroxidase 1 Primary Antibody für IF (p), IHC (p) - ABIN750583
Miyamoto, Tsumuraya, Ohtaki, Dohi, Satoh, Xu, Tanaka, Murai, Watanabe, Sugiyama, Aruga, Shioda: PACAP38 Suppresses Cortical Damage in Mice with Traumatic Brain Injury by Enhancing Antioxidant Activity. in Journal of molecular neuroscience : MN 2014
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Human Polyclonal Glutathione Peroxidase 1 Primary Antibody für ICC, IF - ABIN443480
Sun, Zhang, Zhong, Sun, Zhou: Dietary Fisetin Supplementation Protects Against Alcohol-Induced Liver Injury in Mice. in Alcoholism, clinical and experimental research 2016
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Human Polyclonal Glutathione Peroxidase 1 Primary Antibody für ICC, IF - ABIN4314702
Bachmann, Burté, Pramana, Conte, Brown, Orimadegun, Ajetunmobi, Afolabi, Akinkunmi, Omokhodion, Akinbami, Shokunbi, Kampf, Pawitan, Uhlén, Sodeinde, Schwenk, Wahlgren, Fernandez-Reyes, Nilsson: Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria. in PLoS pathogens 2014
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Human Polyclonal Glutathione Peroxidase 1 Primary Antibody für IHC (p), IHC - ABIN251496
Kato, Kato, Abe, Matsumura, Nishino, Aoki, Itoyama, Asayama, Awaya, Hirano, Ohama et al.: Redox system expression in the motor neurons in amyotrophic lateral sclerosis (ALS): immunohistochemical studies on sporadic ALS, superoxide dismutase 1 (SOD1)-mutated familial ALS, and SOD1-mutated ... in Acta neuropathologica 2005
Human Polyclonal Glutathione Peroxidase 1 Primary Antibody für ELISA, IHC - ABIN6262068
Li, Sun, Liu, Zhao, Shao: Silymarin protects against acrylamide-induced neurotoxicity via Nrf2 signalling in PC12 cells. in Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017
Mouse (Murine) Polyclonal Glutathione Peroxidase 1 Primary Antibody für ELISA, WB - ABIN4314700
Lubos, Kelly, Oldebeken, Leopold, Zhang, Loscalzo, Handy: Glutathione peroxidase-1 deficiency augments proinflammatory cytokine-induced redox signaling and human endothelial cell activation. in The Journal of biological chemistry 2011
Studied the importance of selenium in bovine female reproductive function. Gene expression analysis revealed selenoprotein gene GPX1 was significantly up-regulated in large healthy follicles.
did not find any significant inhibition of bovine GPx-1 by (S)- or (R)-misonidazole.
Data indicate mRNA level and activity of GPx1 are regulated by level of selenium supplied to hepatocytes.
homocysteine decreases GPx1 activity by altering the translational mechanism
glutathione peroxidase-1 activity is decreased by aminoglycosides through interference with selenocysteine incorporation
GPx1 plays a key role in blocking the promotion of porcine circovirus type 2 replication
The developmental expression of GPX1 and thioredoxin reductase during fetal development and the effect of maternal selenium consumption on the expression of these proteins are reported.
Notably, CUEDC2 (zeige CUEDC2 Antikörper) promoted E3 ubiquitin ligases tripartite motif-containing 33 (TRIM33 (zeige TRIM33 Antikörper))-mediated the antioxidant enzyme, glutathione peroxidase 1 (GPX1) ubiquitination, and proteasome-dependent degradation.
GPx1 does not clearly exacerbate hyperoxia-induced increases in oxidative stress or lung injury but may alter pulmonary immune function.
GPx-1 expression deters the unfolded protein response following exposure to cigarette smoke
Glutathione peroxidase 1 (GPx1) knockdown not only induced oxidative stress characterized by the increased production of reactive oxygen species (ROS (zeige ROS1 Antikörper)) but also caused reductive stress indicated by an elevation of glutathione (GSH)/oxidized GSH (GSSG) ratio.
Exposure to far infrared rays significantly protects acute restraint stress oxidative burdens via inhibition of JAK2 (zeige JAK2 Antikörper)/STAT3 (zeige STAT3 Antikörper) signaling by induction of GPx-1.
Genetic inhibition of Gpx1 potentiates cocaine-induced renal damage via activation of AT1R (zeige AGTRAP Antikörper) by inhibition of PI3K-Akt (zeige AKT1 Antikörper) signaling.
Glutathione peroxidase 1 deficiency attenuates concanavalin A-induced liver injury by induction of T-cell hyporesponsiveness through chronic reactive oxygen species exposure.
GPx1 was found to play a critical role in regulating pro-inflammatory pathways in vascular endothelium.
Plasmalogen enrichment via batyl alcohol supplementation attenuated atherosclerosis in ApoE (zeige APOE Antikörper)- and ApoE (zeige APOE Antikörper)/GPx1-deficient mice.
Gpx1 expression in the mouse skeletal muscle can be altered by both exercise and dyslipidemia through changes in DNA methylation (zeige HELLS Antikörper), leading to a fine regulation of free radical metabolism.
there is no correlation between idiopathic male infertility and the GPx1 codon Pro198Leu polymorphism; further studies are needed to investigate other genetic factors that influence the development of idiopathic male infertility
Increased glutathione peroxidase (GPx) activity seemed to compensate for a decrease in GPx1 protein due to enhanced degradation via the proteasome. Mass spectrometry analysis identified Lys (zeige LYZ Antikörper)-114 as a possible carbonylation target which provides a vestibule for the substrate H2O2 and thus enhances the enzymatic reaction
ESR1 (zeige ESR1 Antikörper) and GPX1 expression levels were found to be significantly down-regulated by 14.7% and 7.4% (respectively) in the tumorous breast tissue when compared to the non-malignant one.
The result of this study suggested that GPX1 Pro198Leu polymorphism could not be a risk factor for breast cancer in Rwanda.
No significant differences in allelic or genotypic frequencies of GPX1 rs1050450 or GSTP1 (zeige GSTP1 Antikörper) rs1695 were detected between Chinese schizophrenia cases and controls.
Genetic variations in selenoprotein genes modulated both GPX1 and SELENOP selenoprotein gene expression and global gene expression in response to Brazil nut supplementation.
Allele-specific interaction between GPX1 and MnSOD (zeige SOD2 Antikörper) affects the levels of Bcl2 (zeige BCL2 Antikörper), Sirt3 (zeige SIRT3 Antikörper) and E-cadherin (zeige CDH1 Antikörper).
GPX1, GPX3 and GPX4 may be upregulated in response to a change in oxidative stress during an acute coronary syndromes
The Pro198Leu polymorphism (rs1050450) to the selenoprotein glutathione peroxidase 1 gene (GPX1), and GSTM1 (zeige GSTM1 Antikörper) deletion had no effect on mercury levels in mildly exposed people, suggesting these genetic variants impact mercury levels only in highly exposed populations.
Evaluation of Glutathione Peroxidase and KCNJ11 (zeige KCNJ11 Antikörper) Gene Polymorphisms in Patients with New Onset Diabetes Mellitus After Renal Transplantation
This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
glutathione peroxidase Gpx1
, glutathione peroxidase
, cellular glutathione peroxidase
, cytosolic glutathione peroxidase
, putative glutathione peroxidase
, selenium-dependent glutathione peroxidase 1
, glutathione peroxidase 1
, glutathione peroxidase 1 S homeolog