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The results indicated that epigenetically regulated miR (zeige MLXIP Proteine)-449a targets CREB5 to increase FXRalpha (zeige NR1H4 Proteine) expression, thereby promoting HBV replication and gene expression. Our findings provide a new understanding of the role of miRNAs in HBV replication
High CREB5 expression is associated with triple-negative breast cancer.
LOC401317 is directly regulated by p53 (zeige TP53 Proteine). Ectopic expression of LOC401317 inhibits HNE2 cell proliferation in vitro and in vivo.
CREB5 accelerate the metastasis of colorectal cancer by regulating these five key genes.
The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified.
cAMP responsive element binding protein 5
, cAMP response element binding protein CRE-Bpa
, cAMP response element-binding protein CRE-BPa
, cAMP responsive element binding protein 5 isoform alpha
, cAMP-responsive element-binding protein 5
, cyclic AMP-responsive element-binding protein 5