anti-Human Neurexin 1 Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended Neurexin 1 Antibody

Antigen
Neurexin 1 (NRXN1) Antikörper
  • Hs.22998
  • PTHSL2
  • SCZD17
  • CG7050
  • CT21808
  • Dmel\\CG7050
  • Nrx
  • Nrx1
  • dnrx
  • dnrx-1
  • nrx
  • Nrxn1b
  • NRXN1
  • Nrx-1
  • GB13455
  • GB18754
  • 1700062G21Rik
  • 9330127H16Rik
  • A230068P09Rik
  • mKIAA0578
  • neurexin 1
  • Neurexin 1
  • neurexin I
  • neurexin 1b
  • NRXN1
  • Nrx-1
  • Nrxn1
  • nrxn1
  • nrxn1b
Epitop
AA 40-90
16
15
4
3
2
2
2
2
2
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
77
36
33
4
3
1
Wirt
Kaninchen
55
20
5
2
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
53
41
13
11
5
3
3
2
1
1
1
Optionen

Bilder

Produktnummer ABIN1386379
$ 317.90
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Clonality References Details
1 ABIN1409330 IHC (p) WB HRP Rabbit IgG AA 280-330 Polyclonal 0
1 ABIN1391437 IHC (p) WB Biotin Rabbit IgG AA 280-330 Polyclonal 0
1 ABIN1387438 IF (p) IHC (p) WB Rabbit IgG AA 280-330 Polyclonal 0

General

Antigen Neurexin 1 (NRXN1) Antikörper
Epitop AA 40-90
(16), (15), (4), (3), (2), (2), (2), (2), (2), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(77), (36), (33), (4), (3), (1)
Wirt Kaninchen
(55), (20), (5), (2), (2)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(53), (41), (13), (11), (5), (3), (3), (2), (1), (1), (1)
Hersteller

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Neurexin 1
Isotyp IgG

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Neurexin 1 (NRXN1 Antibody Abstract)
Hintergrund

Neurexins comprise a family of neuronal cell surface proteins, which include neurexin I (NRXN1), neurexin II (NRXN2), neurexin III (NRXN3) and Caspr (neurexin IV). Neurexins I-III are expressed as a and b isoforms. The a isoforms are made of three cassettes, which contain two LNS (Laminin A, Neurexins, Sex hormone-binding)-domains separated by EGF domains, followed by a transmembrane region and a 55 amino acid cytoplasmic C-terminal. The a isoforms bind to neurexophilins at the second LNS site and to the excitatory neurotoxin a-latrotoxin. The b isoforms have only one LNS-domain, bind to neuroligins, and play a role in the formation and remodeling of synapes. Caspr (for Contactin-Associated Protein 1, also designated Paranodin in mouse), contains an extracellular domain similar to the other three neurexins, and binds to the surface glycoprotein Contactin. Caspr and the closely related Caspr2, a mammalian homolog of Drosophila Neurexin IV (Nrx-IV), demarcate distinct subdomains in myelinated axons. Specifically, Caspr exists at the paranodal junctions, while Caspr2 colocalizes with Shaker-like K+ channels in the juxtaparanodal region. Caspr may play a role in the communication of glial cells and neurons during development.

Subcellular location: Extracellular

Synonyms: Neurexin 1 alpha, Neurexin 1 beta, Neurexin I-alpha, Neurexin-1-alpha, NRX1A_HUMAN, NRXN1, PTHSL2.

Gen-ID 9378
UniProt Q9ULB1
Pathways Synaptic Membrane, Skeletal Muscle Fiber Development

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikations-hinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Neurexin 1 (NRXN1) (AA 40-90) antibody (ABIN1386379) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-Neurexin 1 Po...