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anti-Human TRIB1 Antikörper:
anti-Mouse (Murine) TRIB1 Antikörper:
anti-Rat (Rattus) TRIB1 Antikörper:
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Human Polyclonal TRIB1 Primary Antibody für WB - ABIN392118
Dugast, Kiss-Toth, Docherty, Danger, Chesneau, Pichard, Judor, Pettré, Conchon, Soulillou, Brouard, Ashton-Chess: Identification of tribbles-1 as a novel binding partner of Foxp3 in regulatory T cells. in The Journal of biological chemistry 2013
Show all 3 Pubmed References
Human Monoclonal TRIB1 Primary Antibody für ELISA, WB - ABIN564425
Ji, Bian, Yu, Yuan, Liu, Yu, Li, Zhu, Jia, Guan, Zhang, Meng, Jin, Bai, Yu, Lee, Sun, Fu: Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells. in International journal of cancer. Journal international du cancer 2014
Cow (Bovine) Polyclonal TRIB1 Primary Antibody für ELISA - ABIN451704
Sung, Guan, Czibula, King, Eder, Heath, Suvarna, Dower, Wilson, Francis, Crossman, Kiss-Toth: Human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways. in The Journal of biological chemistry 2007
Mouse (Murine) Polyclonal TRIB1 Primary Antibody für ELISA, WB - ABIN4362341
Yokoyama, Kanno, Yamazaki, Takahara, Miyata, Nakamura: Trib1 links the MEK1/ERK pathway in myeloid leukemogenesis. in Blood 2010
our study reveals that TRIB1 promotes CRC (zeige CALR Antikörper) cell migration and invasion by up-regulating the expression of MMP-2 (zeige MMP2 Antikörper) via the activation of FAK (zeige PTK2 Antikörper)/Src (zeige SRC Antikörper) and ERK (zeige EPHB2 Antikörper) pathways, knockdown of TRIB1 expression in CRC (zeige CALR Antikörper) cells abolishes these effects.
role of TRIB1 in cell cycle and survival that is mediated via the modulation of NFkappaB signaling.
the co-operativity observed between MYC (zeige MYC Antikörper) and TRIB1 in the absence of PML (zeige PML Antikörper)/RARA (zeige RARA Antikörper) show that, outside of acute promyelocytic leukemia (zeige PML Antikörper), gain of both genes may drive selection for trisomy 8.
The crucial role of TRIB1 in cisplatin-induced enrichment of CSC and drug resistance was verified by knockdown TRIB1. Interestingly, cisplatin treatment also contributed to the increasement of HDAC (zeige HDAC3 Antikörper), the interaction of TRIB1 with HDAC (zeige HDAC3 Antikörper), and inactivation of p53 (zeige TP53 Antikörper).
Trib1 formed a complex with pHDAC1.
Studies indicate that tribbles homolog 1 (Drosophila) protein appear to be involved in some of the most common diseases, such as cancer, metabolic disease and hyperlipidaemia.
Studies suggest that pseudo-kinase family of tribbles (TRIB) proteins TRIB1, TRIB2 (zeige TRIB2 Antikörper) and TRIB3 (zeige TRIB3 Antikörper) play roles in pathogenesis of rheumatoid arthritis (RA) and osteoarthritis.
Studies indicate that the minor allele of a single nucleotide polymorphism (SNP, rs6982502) in the regulatory sequence reduces the activity of the tribbles homolog 1 (Drosophila) protein (TRIB1) promoter.
Studies suggest that pseudo-kinase family of tribbles (TRIB) proteins TRIB1, TRIB2 (zeige TRIB2 Antikörper) and TRIB3 (zeige TRIB3 Antikörper) were involved in the pathogenesis of inflammation.
Studies indicate that tribbles homolog 1 (Drosophila) protein (TRIB1) interacts with the master molecule of Tregs, forkhead box P3 (FOXP3 (zeige FOXP3 Antikörper)), a transcription factor essential for Treg suppressive activity.
The Liver Clock Controls Cholesterol Homeostasis through Trib1 Protein-mediated Regulation of PCSK9 (zeige PCSK9 Antikörper)/Low Density Lipoprotein Receptor (LDLR (zeige LDLR Antikörper)) Axis.
Deletion of hepatic Trib1 leads to increased C/EBPalpha (zeige CEBPA Antikörper) binding near upregulated lipogenic genes, as well as Trib1 itself.
TRIB1 and TRIB3 (zeige TRIB3 Antikörper) are more strongly expressed than TRIB2 (zeige TRIB2 Antikörper) in cumulus cells (CC) surrounding oocytes from preovulatory follicles than in CC of immature ones.
These data suggested that the modulation of TRIB1 expression affects hepatic lipogenesis and glycogenesis through multiple molecular interactions.
In gene knock-down experiments in macrophages using small interfering RNAs targeted to Trib1, it was observed that TNF-alpha production was increased following treatment with IFN-gamma and/or TLR2 ligands.
These results indicate that COP1 and Trib1 act as an oncoprotein complex functioning upstream of C/EBPalpha (zeige CEBPA Antikörper), and its ligase activity is crucial for leukemogenesis.
tribbles-1 is a novel binding partner of Foxp3 (zeige FOXP3 Antikörper) in regulatory T cells
results demonstrate that Trib1 is critical for adipose tissue maintenance and suppression of metabolic disorders by controlling the differentiation of tissue-resident M2-like macrophages
Trib1-knockout mice showed elevated levels of plasma TG and cholesterol due to increased VLDL production.
Trib1 transduced hematopoietic stem cells developed acute myeloid leukemia (zeige BCL11A Antikörper).
a nuclear factor\; gene expression induced by m1-acetylcholine receptor
tribbles homolog 1 (Drosophila)
, G-protein-coupled receptor induced protein
, phosphoprotein C8FW
, tribbles homolog 1
, G-protein-coupled receptor-induced gene 2 protein
, G-protein-coupled receptor-induced protein 2
, phosphoprotein regulated by mitogenic pathways
, tribbles-like protein 1
, G-protein-coupled receptor induced protein GIG2