anti-Human E-cadherin Antikörper für Immunohistochemistry (Frozen Sections)

Recommended E-cadherin Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Antikörper
  • Arc-1
  • CD324
  • CDHE
  • ECAD
  • LCAM
  • UVO
  • E-cadherin
  • cdh1
  • si:dz180o5.2
  • uvo
  • lcam
  • E-Cad
  • XBcad
  • l-cam
  • xcdh1
  • cdhc-A
  • xb-cad
  • XTCAD-1
  • c-cadherin
  • cadherin-1
  • uvomorulin
  • XB-cadherin
  • arc-1
  • cd324
  • cdhe
  • ecad
  • AA960649
  • E-cad
  • Ecad
  • L-CAM
  • Um
  • cadherin 1
  • si:busm1-180o5.2
  • cadherin 1, type 1, E-cadherin (epithelial)
  • cadherin 1, type 1 S homeolog
  • CDH1
  • si:busm1-180o5.2
  • cdh1
  • Cdh1
  • cdh1.S
Epitop
AA 286-703
98
35
26
21
19
16
16
15
15
14
10
7
6
6
6
6
5
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
802
238
143
40
26
16
9
8
8
7
6
4
3
1
1
1
1
1
1
1
1
Wirt
Kaninchen
548
264
37
22
2
Klonalität
Polyklonal
Konjugat
Dieser E-cadherin Antikörper ist unkonjugiert
43
39
34
31
24
21
21
17
17
15
13
13
13
13
12
12
11
10
8
7
7
6
4
3
3
3
3
3
3
2
2
Applikation
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
638
369
275
214
189
170
157
88
86
38
19
14
13
12
10
7
6
6
4
2
2
2
2
2
1
1
1
Optionen
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Bilder

Produktnummer ABIN3043808
$ 280.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1106274 IHC (fro) IF IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 5H9 2
1 ABIN265912 ICC IHC (fro) IF IP IHC MA WB Rat IgG1 Anmelden zum Anzeigen DECMA-1 2
1 ABIN614765 IHC (fro) FACS IF IP WB Mouse IgG1 Anmelden zum Anzeigen 67A4 12
1 ABIN112362 FACS IHC (fro) IF WB Mouse IgG2b Anmelden zum Anzeigen MB2 3
1 ABIN4306562 CyTOF FACS ICC IF IHC IHC (fro) IP WB Mouse IgG1 Anmelden zum Anzeigen 67A4 1
1 ABIN459320 ICC IHC (fro) IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 5H9 4
1 ABIN111950 FACS IHC (fro) Mouse IgG1 Anmelden zum Anzeigen 67A4-2-1 0
1 ABIN1859234 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 373-621 Anmelden zum Anzeigen Polyclonal 0
1 ABIN3201214 ICC IHC (fro) IHC (p) ELISA WB Mouse IgG AA 155-882 Anmelden zum Anzeigen 0
1 ABIN959445 IHC (fro) WB Mouse IgG1 Anmelden zum Anzeigen 5H9 0
1 ABIN959472 IHC (fx) IHC (fro) FACS WB Mouse IgG2b Anmelden zum Anzeigen MB2 0
1 ABIN1996065 IHC (fro) IF IHC (p) ELISA WB Rabbit IgG AA 1-707 Anmelden zum Anzeigen Polyclonal 0
1 ABIN335398 ICC FACS IHC (fro) IHC WB Mouse IgG2b Anmelden zum Anzeigen MB2 3
1 ABIN4306569 CyTOF FACS ICC IF IHC IHC (fro) WB Mouse IgG2b Anmelden zum Anzeigen MB2 0
1 ABIN4306574 FACS ICC IF IHC IHC (fro) WB Mouse IgG2b Anmelden zum Anzeigen MB2 0
1 ABIN4306570 ICC IF IHC IHC (fro) IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 5H9 0
1 ABIN4306563 ICC IF IHC IHC (fro) IP MA WB Rat IgG1 Anmelden zum Anzeigen DECMA-1 0
1 ABIN198432 FACS IHC (fro) IF IHC (p) IP WB Rat IgG2a Anmelden zum Anzeigen ECCD-2 0
1 ABIN959449 ICC IHC (fro) WB Mouse IgG1 Anmelden zum Anzeigen 6F9 0
1 ABIN490144 ICC FACS IHC (fro) IP WB Mouse IgG1 Anmelden zum Anzeigen 67A4 0

General

Antigen Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Antikörper
Epitop AA 286-703
(98), (35), (26), (21), (19), (16), (16), (15), (15), (14), (10), (7), (6), (6), (6), (6), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(802), (238), (143), (40), (26), (16), (9), (8), (8), (7), (6), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(548), (264), (37), (22), (2)
Klonalität
Polyklonal
Konjugat Dieser E-cadherin Antikörper ist unkonjugiert
(43), (39), (34), (31), (24), (21), (21), (17), (17), (15), (13), (13), (13), (13), (12), (12), (11), (10), (8), (7), (7), (6), (4), (3), (3), (3), (3), (3), (3), (2), (2)
Applikation Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
(638), (369), (275), (214), (189), (170), (157), (88), (86), (38), (19), (14), (13), (12), (10), (7), (6), (6), (4), (2), (2), (2), (2), (2), (1), (1), (1)
Pubmed 12 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-E-cadherin Antikörper

Target Details E-cadherin Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN3043808) Bilder
Verwendungszweck Rabbit IgG polyclonal antibody for Cadherin-1(CDH1) detection. Tested with WB, IHC-P, IHC-F, ELISA in Human.
Kreuzreaktivität (Details) No cross reactivity with other proteins.
Produktmerkmale Rabbit IgG polyclonal antibody for Cadherin-1(CDH1) detection. Tested with WB, IHC-P, IHC-F, ELISA in Human.
Gene Name: cadherin 1, type 1, E-cadherin (epithelial)
Protein Name: Cadherin-1
Reinigung Immunogen affinity purified.
Immunogen E.coli-derived human E Cadherin recombinant protein (Position: A286-A703). Human E Cadherin shares 79.7% and 80.9% amino acid (aa) sequence identity with mouse and rat E Cadherin, respectively.
Isotyp IgG

Target Details E-cadherin

Produktdetails anti-E-cadherin Antikörper Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN3043808) Bilder zurück nach oben
Antigen
Andere Bezeichnung CDH1 (CDH1 Antibody Abstract)
Hintergrund CDH1 (Cadherin 1), also known as ECAD or UVO, is a protein that in humans is encoded by the CDH1 gene. Cadherin-1 is a classical member of the cadherin superfamily. By Southern analysis of DNA from a panel of mouse-human somatic cell hybrids, Mansouri et al. (1987, 1988) assigned the UVO gene to 16q (16p11-qter). Frebourg et al. (2006) found that in human embryos CDH1 is highly expressed at 4 and 5 weeks in the frontonasal prominence and at 6 weeks in the lateral and medial nasal prominences, and is therefore expressed during critical stages of lip and palate development. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.

Synonyms: Arc 1 antibody|CADH1_HUMAN antibody|Cadherin 1 antibody|cadherin 1 type 1 E-cadherin antibody|Cadherin1 antibody|CAM 120/80 antibody|CD 234 antibody|CD 324 antibody|CD324 antibody|CD324 antigen antibody|CDH1 antibody|CDHE antibody|E-Cad/CTF3 antibody|E-cadherin antibody|ECAD antibody|Epithelial cadherin antibody|epithelial calcium dependant adhesion protein antibody|LCAM antibody|Liver cell adhesion molecule antibody|UVO antibody| Uvomorulin antibody
Gen-ID 999
UniProt P12830
Forschungsgebiet Proteolysis / Ubiquitin
Pathways Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation

Anwendungsinformationen

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN3043808) Bilder zurück nach oben
Applikationshinweise WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Kommentare

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Referenzen für anti-E-cadherin Antikörper (ABIN3043808) Bilder zurück nach oben
Format Lyophilized
Rekonstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Konzentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-E-cadherin Antikörper (ABIN3043808)

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Li, Chen, Zeng, Li, Zhang, Lin, Zhang, Xie, He, Shu, Yang, Tang, Fu: "Matrigel basement membrane matrix induces eccrine sweat gland cells to reconstitute sweat gland-like structures in nude mice." in: Experimental cell research, Vol. 332, Issue 1, pp. 67-77, 2015

Deng, Zhang, Zhang, Wen, Miao, Guo: "MicroRNA-142-3p inhibits cell proliferation and invasion of cervical cancer cells by targeting FZD7." in: Tumour biology, 2015

Duan, Lin, Li, Ding, Qian, Zhang, Ge, Fan, Li: "Effects of inhibition of hedgehog signaling on cell growth and migration of uveal melanoma cells." in: Cancer biology & therapy, Vol. 15, Issue 5, pp. 544-59, 2014

Han, Fu, Luo, He, Liu, Liao, Tian, Yan: "BVES inhibition triggers epithelial-mesenchymal transition in human hepatocellular carcinoma." in: Digestive diseases and sciences, Vol. 59, Issue 5, pp. 992-1000, 2014

Wang, Zhao, Tang, Wu, Yao, Zhang: "Overexpressions of microRNA-9 and microRNA-200c in human breast cancers are associated with lymph node metastasis." in: Cancer biotherapy & radiopharmaceuticals, Vol. 28, Issue 4, pp. 283-8, 2014

Li, Lv, Wu, Zhang, Liu, Liu: "Dexamethasone prevents monocyte-induced tubular epithelial-mesenchymal transition in HK-2 cells." in: Journal of cellular biochemistry, Vol. 114, Issue 3, pp. 632-8, 2013

Shen, Xie, Shen, liu, Zheng, Kou, Wang, Yang: "Negative correlation of LIV-1 and E-cadherin expression in hepatocellular carcinoma cells." in: PLoS ONE, Vol. 8, Issue 2, pp. e56542, 2013

Wang, Zhang, Song, Liu, Zhang, Wang, Lv: "Astaxanthin ameliorates lung fibrosis in vivo and in vitro by preventing transdifferentiation, inhibiting proliferation, and promoting apoptosis of activated cells." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 56, pp. 450-8, 2013

Jin, Guo, Che, Sun, Liu, Zhang: "Germline stem cell lineage tracing by free-floating immunofluorescent assay of mouse seminiferous tubule." in: Microscopy research and technique, Vol. 75, Issue 8, pp. 1150-3, 2012

Tang, Yang, Tao, You, An, Li, Wu, Liu: "Epithelial-mesenchymal transdifferentiation of renal tubular epithelial cells induced by urinary proteins requires the activation of PKC-? and ?I isozymes." in: Cell biology international, Vol. 35, Issue 9, pp. 953-9, 2011

Xia, Cheung, Sze, Lu, Jiang, Yao, Bian, Poon, Kung, Lin: "miR-200a regulates epithelial-mesenchymal to stem-like transition via ZEB2 and beta-catenin signaling." in: The Journal of biological chemistry, Vol. 285, Issue 47, pp. 36995-7004, 2010

Shen, Qin, Guo: "Concordant correlation of LIV-1 and E-cadherin expression in human breast cancer cell MCF-7." in: Molecular biology reports, Vol. 36, Issue 4, pp. 653-9, 2009

Bilder

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN3043808) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 286-703) antibody (ABIN3043808) anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 286-703) antibody
Western Blotting (WB) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 286-703) antibody (ABIN3043808) Observed bind size: 140KD
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 286-703) antibody (ABIN3043808) anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 286-703) antibody (Image 3)