anti-Ratte (Rattus) VEGFC Antikörper für Enzyme Immunoassay

Recommended VEGFC Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Vascular Endothelial Growth Factor C (VEGFC) Antikörper
  • VEGFC
  • vegf-c
  • xvegf-c
  • Flt4-L
  • VRP
  • AW228853
  • VEGF-C
  • vascular endothelial growth factor c
  • vascular endothelial growth factor C
  • vascular endothelial growth factor C S homeolog
  • vegfc
  • VEGFC
  • vegfc.S
  • Vegfc
Reaktivität
Human, Ratte (Rattus)
245
94
93
3
3
2
2
2
1
1
1
1
Wirt
Maus
182
123
8
1
1
1
Klonalität
Monoklonal
Konjugat
Dieser VEGFC Antikörper ist unkonjugiert
30
25
19
8
7
7
5
5
4
4
4
4
4
4
4
4
4
3
3
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
265
156
136
43
25
23
23
17
17
17
13
8
3
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN360868
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN115678 EIA IP Rabbit Anmelden zum Anzeigen Polyclonal 1
1 ABIN115679 EIA IP Rabbit Anmelden zum Anzeigen Polyclonal 0
1 ABIN5540710 EIA Biotin Rabbit IgG AA 101-221 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Vascular Endothelial Growth Factor C (VEGFC) Antikörper
Reaktivität Human, Ratte (Rattus)
(245), (94), (93), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Wirt Maus
(182), (123), (8), (1), (1), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser VEGFC Antikörper ist unkonjugiert
(30), (25), (19), (8), (7), (7), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Western Blotting (WB)
(265), (156), (136), (43), (25), (23), (23), (17), (17), (17), (13), (8), (3)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-VEGFC Antikörper

Target Details VEGFC Anwendungsinformationen Handhabung Referenzen für anti-VEGFC Antikörper (ABIN360868) Bilder
Spezifität This antibody detects VEGF-C in Western Blots. No cross-reactivity is shown with VEGF-A.
Reinigung Protein G Affinity Chromatography
Immunogen Recombinant Human VEGF-C protein (Cat.-No AR01001PU-N)
Klon 107F10
Isotyp IgG2a
Plasmids, Primers & others

Target Details VEGFC

Produktdetails anti-VEGFC Antikörper Anwendungsinformationen Handhabung Referenzen für anti-VEGFC Antikörper (ABIN360868) Bilder zurück nach oben
Antigen
Andere Bezeichnung VEGF-C / Flt4-L (VEGFC Antibody Abstract)
Hintergrund VEGF-C, also known as Vascular Endothelial Growth Factor Related Protein (VRP), is a recently discovered VEGF growth factor family member that is most closely related to VEGF-D. The human VEGF-C cDNA encodes a pre-pro-protein of 416 amino acids residues. It is almost identical to the mouse VEGF-C protein. Similar to VEGF-D, VEGF-C has a VEGF homology domain spanning the middle third of the precursor molecule and long N- and C-terminal extensions. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. Recombinant human VEGF-C, lacking the N- and C-terminal extensions and containing only the middle VEGF homology domain, forms primarily non-covalently linked dimers. This protein is a ligand for both VEGFR-2/KDR and VEGFR-3/FLT-4. Since VEGFR-3 is strongly expressed in lymphatic endothelial cells, it has been postulated that VEGF-C is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. Although recombinant human VEGF-C is also a mitogen for vascular endothelial cells, it is much less potent than VEGF-A. The recombinant human VEGF-C contains 115 amino acids residues and was fused to a His-tag (6x His) at the C-terminal end. As a result of glycosylation VEGF-C migrates as an 18-24 kDa protein in SDS-PAGE under reducing conditions.Synonyms: Flt4 ligand, VEGFC, VRP, Vascular endothelial growth factor C, Vascular endothelial growth factor-related protein
Gen-ID 7424
NCBI Accession NP_005420
UniProt P49767
Pathways RTK Signalweg, Signaling Events mediated by VEGFR1 and VEGFR2

Anwendungsinformationen

Produktdetails anti-VEGFC Antikörper Target Details VEGFC Handhabung Referenzen für anti-VEGFC Antikörper (ABIN360868) Bilder zurück nach oben
Applikations-hinweise Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-VEGFC Antikörper Target Details VEGFC Anwendungsinformationen Referenzen für anti-VEGFC Antikörper (ABIN360868) Bilder zurück nach oben
Rekonstitution Restore in sterile water to a concentration of 0.1-1.0 mg/mL. Centrifuge vial prior to opening.
Buffer PBS without preservatives or stabilizers
Konservierungs-mittel Without preservative
Handhabung Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Prior to reconstitution store at 2-8 °C. Following reconstitution store at -20 °C. This product should be stored undiluted.

Referenzen für anti-VEGFC Antikörper (ABIN360868)

Produktdetails anti-VEGFC Antikörper Target Details VEGFC Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Olofsson, Jeltsch, Eriksson, Alitalo: "Current biology of VEGF-B and VEGF-C." in: Current opinion in biotechnology, Vol. 10, Issue 6, pp. 528-35, 2000

Joukov, Pajusola, Kaipainen, Chilov, Lahtinen, Kukk, Saksela, Kalkkinen, Alitalo: "A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases." in: The EMBO journal, Vol. 15, Issue 2, pp. 290-98, 1996