anti-Maus Phospholipase C gamma 2 Antikörper für Enzyme Immunoassay

Recommended Phospholipase C gamma 2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Phospholipase C gamma 2 (PLCG2) Antikörper
  • PLCgamma2
  • Plcg-2
  • APLAID
  • FCAS3
  • phospholipase C, gamma 2
  • phospholipase C gamma 2
  • phospholipase C, gamma 2 (phosphatidylinositol-specific)
  • Plcg2
  • PLCG2
Reaktivität
Human, Maus, Ratte (Rattus)
330
164
155
12
4
4
4
4
3
1
Wirt
Kaninchen
221
109
Klonalität
Polyklonal
Konjugat
Dieser Phospholipase C gamma 2 Antikörper ist unkonjugiert
9
9
8
8
8
5
5
5
5
5
5
5
5
5
5
3
3
3
3
3
3
3
3
3
3
3
3
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
241
136
105
66
56
44
40
34
14
11
6
3
2
Hersteller
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Bilder

Produktnummer ABIN271905
$ 390.50
Zzgl. Versandkosten $45.00

General

Antigen Phospholipase C gamma 2 (PLCG2) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(330), (164), (155), (12), (4), (4), (4), (4), (3), (1)
Wirt Kaninchen
(221), (109)
Klonalität
Polyklonal
Konjugat Dieser Phospholipase C gamma 2 Antikörper ist unkonjugiert
(9), (9), (8), (8), (8), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(241), (136), (105), (66), (56), (44), (40), (34), (14), (11), (6), (3), (2)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Phospholipase C gamma 2 Antikörper

Target Details Phospholipase C gamma 2 Anwendungsinformationen Handhabung Bilder
Spezifität This antibody detects endogenous levels of PLCG2 protein. (region surrounding Arg747)
Kreuzreaktivität (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Reinigung Affinity Chromatography using epitope-specific immunogen

Target Details Phospholipase C gamma 2

Produktdetails anti-Phospholipase C gamma 2 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung PLCG2 (PLCG2 Antibody Abstract)
Hintergrund Phosphoinositide-specific phospholipase C (PLC) plays a crucial role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5-triphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. There are many mammalian PLC isozymes, including PLC β1, PLC β2, PLC β3, PLC β4, PLCγ1, PLCγ2, PLC δ1, PLC δ2 and PLCe. PLCδ exists as four different isoforms. PLC δ1, a calcium signal amplifier, is activated by an atypical GTP-binding protein. In addition, PLC δ1 is an effector for GTP-binding protein transglutaminase II-mediated oxytocin receptor and α1B-adrenoreceptor signaling. Mouse PLC δ1 is highly expressed in brain, heart, lung and testis. PLC δ is abnormally accumulated in autopsied brains with Alzheimer's disease (AD), suggesting that it may play a role in the pathology of AD. PLC δ2 is markedly expressed in type II intestinal metaplasia and in the adenocarcinoma. When PLC δ2 is expressed in type I intestinal metaplasia, the metaplasia is generally considered benignant, yet evolves toward neoplastic transformation. Thus, PLC δ2 expression may be a possible marker of gastric malignant transformation.Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-2, PLC-IV, PLC-gamma-2, Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, Phospholipase C-gamma-2
Molekulargewicht approx. 148 kDa
Gen-ID 5336
NCBI Accession NP_002652
UniProt P16885
Pathways RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling

Anwendungsinformationen

Produktdetails anti-Phospholipase C gamma 2 Antikörper Target Details Phospholipase C gamma 2 Handhabung Bilder zurück nach oben
Applikations-hinweise ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Phospholipase C gamma 2 Antikörper Target Details Phospholipase C gamma 2 Anwendungsinformationen Bilder zurück nach oben
Konzentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Bilder

Produktdetails anti-Phospholipase C gamma 2 Antikörper Target Details Phospholipase C gamma 2 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
 image for anti-Phospholipase C gamma 2 (PLCG2) antibody (ABIN271905) anti-Phospholipase C gamma 2 (PLCG2) antibody
 image for anti-Phospholipase C gamma 2 (PLCG2) antibody (ABIN271905) anti-Phospholipase C gamma 2 (PLCG2) antibody (Image 2)