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Mouse (Murine) PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN413709
Hamada, Gonda, Takeda, Sato, Watanabe, Yambe, Satomi, Ohuchi: In vivo imaging of the molecular distribution of the VEGF receptor during angiogenesis in a mouse model of ischemia. in Blood 2011
Human PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN413706
Tsuchida, Schneider, Pizani, Oliveira: Lead and aluminum bonding in Pb-AI metaphosphate glasses. in Inorganic chemistry 2008
Human PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN1590225
Lim, Moon, Shin, Kim, Cho, Kim, Park, Choi, Ko, Chung, Lee, Jang, Kim, Park: Effect of S-adenosylmethionine on neointimal formation after balloon injury in obese diabetic rats. in Cardiovascular research 2011
Human PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN804609
Huang, Zhao, Fields, Ransohoff, Zhou: Imatinib attenuates skeletal muscle dystrophy in mdx mice. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009
Human PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN1589629
Rezzola, Dal Monte, Belleri, Bugatti, Chiodelli, Corsini, Cammalleri, Cancarini, Morbidelli, Oreste, Bagnoli, Semeraro, Presta: Therapeutic Potential of Anti-Angiogenic Multitarget N,O-Sulfated E. Coli K5 Polysaccharide in Diabetic Retinopathy. in Diabetes 2015
PDGF-B (zeige PDGFB Proteine) expression was found in ovarian tumor microvessels in 72% of cases. High expression of PDGF (zeige PDGFA Proteine) in pericapillary cells was strongly associated with high expression of this marker in cancer cells. Significant correlations between PDGF-B (zeige PDGFB Proteine) and nestin (zeige NES Proteine) expression in malignant tumor microvessels were also found.
SOX7 transcription factor (zeige SOX7 Proteine) mediates PDGF (zeige PDGFA Proteine)-BB-induced IL-33 (zeige IL33 Proteine) expression.
High expression of PDGF (zeige PDGFA Proteine)-BB may be involved in the pathogenesis of Graves' disease. CCR2 (zeige CCR2 Proteine)-positive macrophages may induce the expression of PDGF (zeige PDGFA Proteine)-BB through HIF-1alpha (zeige HIF1A Proteine) signal.
rhPDGF-BB promoted the proliferation of hADSCs via miR (zeige MLXIP Proteine)-363/PI3K (zeige PIK3CA Proteine)/Akt (zeige AKT1 Proteine) pathway, indicating that rhPDGF-BB combined with ADSCs could treat Achilles tendinitis via miR (zeige MLXIP Proteine)-363/PI3K (zeige PIK3CA Proteine)/Akt (zeige AKT1 Proteine) pathway.
This review showed that PDGFB was one of the common gene involved included with brain calcification.
Rare Skin Tumor Dermatofibrosarcoma Protuberans (DFSP) is characterized by the translocation of the PDGFB (zeige PDGFB Proteine) gene to the collagen 1A1 (zeige COL1A1 Proteine) gene.
Transglutaminase type 2 affects cell migration through post-translational modification of PDGF (zeige PDGFA Proteine)-BB.
PDGF-B (zeige PDGFB Proteine) rs1800818 polymorphism might play a role in mediating the susceptibility to severe fever with thrombocytopenia syndrome in Chinese individuals.
PDAP-1 (zeige PDAP1 Proteine) as an effecter of PDGF (zeige PDGFA Proteine) signaling in glioma cells
High PDGFB expression is associated with gastric cancer.
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
PDGF subunit B
, PDGF, B chain
, platelet-derived growth factor 2
, platelet-derived growth factor B chain
, platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
, platelet-derived growth factor subunit B
, platelet-derived growth factor, beta polypeptide (oncogene SIS)
, proto-oncogene c-Sis