Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Weitere Synonyme anzeigen
Wählen Sie die gewünschte Spezies
Data show that Rab GTPase (zeige RAB24 Proteine) Rab44 affects nuclear factor of activated T-cells c1 (NFATc1) signaling in RANKL (zeige TNFSF11 Proteine)-stimulated macrophages.
A threshold level of NFATc1 activity facilitates thymocyte differentiation and opposes Notch3 (zeige NOTCH3 Proteine)-driven leukemia development.
our data suggested that purpurogallin inhibits osteoclast differentiation via downregulation of c-Fos and NFATc1
the CD137 (zeige TNFRSF9 Proteine)-CD137L (zeige TNFSF9 Proteine) pathway plays an important role in regulating VSMC phenotype transformation via activation of NFATc1 signaling pathway.
Loss of NFATC1 is associated with Bone resorption.
Berberine hydrochloride targets TRAF6 (zeige TRAF6 Proteine) and NFATc1.
RCANs play critical roles in bone homeostasis by regulating both osteoclastogenesis and osteoblastogenesis, and they serve as inhibitors for calcineurin-NFATc1 signaling both in vivo and in vitro.
APC (zeige APC Proteine) defines Treg differentiation and anti-inflammatory function through microtubule-mediated NFAT localization.
Tusc2/Fus1 (zeige TUSC2 Proteine) regulates osteoclast differentiation through NF-kappaB (zeige NFKB1 Proteine) and NFATc1
these data demonstrated that wedelolactone facilitated osteoblastogenesis through Wnt (zeige WNT2 Proteine)/GSK3beta/beta-catenin (zeige CTNNB1 Proteine) signaling pathway and suppressed RANKL (zeige TNFSF11 Proteine)-induced osteoclastogenesis through NF-kappaB (zeige NFKB1 Proteine)/c-fos/NFATc1 pathway.
A novel role of HPV oncoprotein in facilitating NFAT2 dependent cell proliferation.
There is a correlation between NFATC1 genes and the incidence of congenital heart disease in children, and a correlation between different genotypes and allele frequency and the incidence of the disease.
Increased expression of nuclear factor of activated T cells 1 drives IL-9 (zeige IL9 Proteine)-mediated allergic asthma.
NFATc1 knockdown strongly reduced the number and the surface area of myotubes, NFATc4 (zeige NFATC4 Proteine) knockdown increased the surface area of myotubes and reduced the pool of reserve cells.
NFAT2 is an important regulator for the anergic phenotype of chronic lymphocytic leukaemia.
Exposure to UVB radiation induces nuclear translocation and stimulates binding between NFAT5 (zeige NFAT5 Proteine) and NF-kappaB (zeige NFKB1 Proteine) proteins in HLE (zeige ELANE Proteine)-B3 cells. These interactions may form part of the biochemical mechanism of cataractogenesis in UVB-irradiated HLECs.
data identified a novel role of SFKs in preventing aberrant NFAT1 (zeige NFAT1 Proteine) activation in resting T cells, and suggest that maintaining this pool of active SFKs in therapeutic T cells may increase the efficacy of T cell therapies
Pathway analysis of the genes associated with the 46 CpG sites revealed an enrichment of immune system process genes, including LYST (cg16962115, FDR = 1.24E-04), CADM1 (zeige CADM1 Proteine) (cg21933078, FDR = 1.22E-02) and NFATC1 (cg06784563, FDR = 1.46E-02)
there is an NFATc1/ABCA1 (zeige ABCA1 Proteine)-dependent mechanism in which local TNF (zeige TNF Proteine) is sufficient to cause free cholesterol-dependent podocyte injury irrespective of TNF (zeige TNF Proteine), TNFR1 (zeige TNFRSF1A Proteine), or TNFR2 (zeige TNFRSF1B Proteine) serum levels
In calf pulmonary artery endothelial cells, extracellular application of vasoactive agonist ATP or calcium ionophore ionomycin generates a rise in intracellular calcium that induces nuclear localization of NFATc1.
regulation of nuclear localization of NFAT is isoform-specific and dependent on nuclear export processes
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
, nuclear factor of activated T-cells, cytosolic component 1
, nuclear factor of activated T-cells calcineurin-dependent 1
, nuclear factor of activated T-cells, cytoplasmic 1
, nuclear factor of activated T-cells, cytoplasmic 1-like
, NFAT transcription complex cytosolic component
, transcription factor NF-ATc
, transcription factor NFATmac