anti-Human MCK10 Antikörper für Flow Cytometry

Recommended MCK10 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Discoidin Domain Receptor Family, Member 1 (DDR1) Antikörper
  • DDR1
  • DDR
  • 6030432F18
  • AI323681
  • CD167a
  • Cak
  • Nep
  • PTK3A
  • CAK
  • CD167
  • EDDR1
  • HGK2
  • MCK10
  • NEP
  • NTRK4
  • PTK3
  • RTK6
  • TRKE
  • Drd1
  • PTK3D
  • discoidin domain receptor tyrosine kinase 1
  • discoidin domain receptor family, member 1
  • DDR1
  • ddr1
  • Ddr1
Reaktivität
Human
20
8
8
Wirt
Maus
16
4
Klonalität
Monoklonal
Konjugat
Dieser MCK10 Antikörper ist konjugiert mit PE
1
1
1
Applikation
Flow Cytometry (FACS)
14
7
4
3
2
2
2
1
1
Hersteller
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Bilder

Produktnummer ABIN2663088
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
13.27586 ABIN2664284 FACS Mouse IgG3 kappa Anmelden zum Anzeigen 51D6 4
1 ABIN5552246 EIA FACS IHC (p) WB Rabbit Ig Fraction N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN2663089 FACS PE Mouse IgG3 kappa Anmelden zum Anzeigen 51D6 5

General

Antigen Discoidin Domain Receptor Family, Member 1 (DDR1) Antikörper
Reaktivität Human
(20), (8), (8)
Wirt Maus
(16), (4)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser MCK10 Antikörper ist konjugiert mit PE
(1), (1), (1)
Applikation Flow Cytometry (FACS)
(14), (7), (4), (3), (2), (2), (2), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-MCK10 Antikörper

Target Details MCK10 Anwendungsinformationen Handhabung Referenzen für anti-MCK10 Antikörper (ABIN2663088) Bilder
Produktmerkmale The 51D6 monclonal antibody recognizes human CD167a also known as discoidin domain receptor, DDR1, neuroepithelial tyrosine kinase, epithelial-specific receptor kinase, tyrosine kinase receptor E (trkE), cell adhesion kinase (CAK), PTK3, and RTK6. CD167a is a membrane type II receptor kinase, containing a factor VIII-like domain. At least five isoforms are generated through alternative splicing of the kinase domain of human DDR1 gene. These isoforms are named wtih suffixes a to e. CD167a is expressed on epithelial cells, keratinocytes, leukocytes, monocytes and has been reported to be overexpressed in some breast carcinomas. CD167a expression can be upregulated by p53. CD167a has been reported to interact with a variety of proteins including collagen type II alpha 1, collagen type III alpha 1, collagen type V alpha 2, collagen type XI alpha 1, phospholipase gamma 1, SHC, and the lipid-anchored docking protein FRS2. CD167a can be phosphorylated on Y513. Animal studies suggest that CD167a is involved in arterial wound healing. The 51D6 antibody has been shown to be useful for flow cytometric detection of human CD167a as well as immunoprecipitation.
Reinigung The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Klon 51D6
Isotyp IgG3 kappa

Target Details MCK10

Produktdetails anti-MCK10 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-MCK10 Antikörper (ABIN2663088) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD167a (DDR1 Antibody Abstract)
Pathways RTK Signalweg, Smooth Muscle Cell Migration

Anwendungsinformationen

Produktdetails anti-MCK10 Antikörper Target Details MCK10 Handhabung Referenzen für anti-MCK10 Antikörper (ABIN2663088) Bilder zurück nach oben
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-MCK10 Antikörper Target Details MCK10 Anwendungsinformationen Referenzen für anti-MCK10 Antikörper (ABIN2663088) Bilder zurück nach oben
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Protect from prolonged exposure to light. Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

Referenzen für anti-MCK10 Antikörper (ABIN2663088)

Produktdetails anti-MCK10 Antikörper Target Details MCK10 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Rudra-Ganguly, Lowe, Mattie, Chang, Satpayev, Verlinsky, An, Hu, Yang, Challita-Eid, Stover, Pereira: "Discoidin domain receptor 1 contributes to tumorigenesis through modulation of TGFBI expression." in: PLoS ONE, Vol. 9, Issue 11, pp. e111515, 2014

Hou, Vogel, Bendeck: "The discoidin domain receptor tyrosine kinase DDR1 in arterial wound repair." in: The Journal of clinical investigation, Vol. 107, Issue 6, pp. 727-35, 2001

Sakuma, Saya, Tada, Nakao, Fujiwara, Roth, Sawamura, Shinohe, Abe: "Receptor protein tyrosine kinase DDR is up-regulated by p53 protein." in: FEBS letters, Vol. 398, Issue 2-3, pp. 165-9, 1997

Di Marco, Cutuli, Guerra, Cancedda, De Luca: "Molecular cloning of trkE, a novel trk-related putative tyrosine kinase receptor isolated from normal human keratinocytes and widely expressed by normal human tissues." in: The Journal of biological chemistry, Vol. 268, Issue 32, pp. 24290-5, 1993

Johnson, Edman, Rutter: "A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 12, pp. 5677-81, 1993

Bilder

Produktdetails anti-MCK10 Antikörper Target Details MCK10 Anwendungsinformationen Handhabung Referenzen für anti-MCK10 Antikörper (ABIN2663088) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Discoidin Domain Receptor Family, Member 1 (DDR1) antibody (PE) (ABIN2663088) anti-Discoidin Domain Receptor Family, Member 1 (DDR1) antibody (PE)