anti-Human MCK10 Antikörper für Enzyme Immunoassay

Recommended MCK10 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Discoidin Domain Receptor Family, Member 1 (DDR1) Antikörper
  • DDR1
  • DDR
  • 6030432F18
  • AI323681
  • CD167a
  • Cak
  • Nep
  • PTK3A
  • CAK
  • CD167
  • EDDR1
  • HGK2
  • MCK10
  • NEP
  • NTRK4
  • PTK3
  • RTK6
  • TRKE
  • Drd1
  • PTK3D
  • discoidin domain receptor tyrosine kinase 1
  • discoidin domain receptor family, member 1
  • DDR1
  • ddr1
  • Ddr1
Reaktivität
Human
19
7
6
Wirt
Kaninchen
15
5
Klonalität
Polyklonal
Konjugat
Dieser MCK10 Antikörper ist unkonjugiert
2
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
15
6
5
4
3
3
2
1
1
Hersteller
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Bilder

Produktnummer ABIN359899
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN614409 EIA IHC (p) WB Mouse IgG1 AA 602-681 Anmelden zum Anzeigen 2G4E12 0
1 ABIN5552246 EIA FACS IHC (p) WB Rabbit Ig Fraction N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN5552219 EIA WB Rabbit Ig Fraction Middle Region Anmelden zum Anzeigen Polyclonal 0

General

Antigen Discoidin Domain Receptor Family, Member 1 (DDR1) Antikörper
Reaktivität Human
(19), (7), (6)
Wirt Kaninchen
(15), (5)
Klonalität
Polyklonal
Konjugat Dieser MCK10 Antikörper ist unkonjugiert
(2)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(15), (6), (5), (4), (3), (3), (2), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-MCK10 Antikörper

Target Details MCK10 Anwendungsinformationen Handhabung Referenzen für anti-MCK10 Antikörper (ABIN359899) Bilder
Spezifität This antibody reacts to MCK10.
Reinigung Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with recombinant human MCK10 protein.
Isotyp Ig Fraction
Plasmids, Primers & others

Target Details MCK10

Produktdetails anti-MCK10 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-MCK10 Antikörper (ABIN359899) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD167a / DDR1 (DDR1 Antibody Abstract)
Hintergrund Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. MCK10 is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain.Synonyms: CAK, CD167 antigen-like family member A, EDDR1, Epithelial discoidin domain receptor 1, Epithelial discoidin domain-containing receptor 1, MCK10, NEP, NTRK4, PTK3A, RTK6, TRKE, Tyrosine kinase DDR-1
Gen-ID 780, 9606
UniProt Q08345
Pathways RTK Signalweg, Smooth Muscle Cell Migration

Anwendungsinformationen

Produktdetails anti-MCK10 Antikörper Target Details MCK10 Handhabung Referenzen für anti-MCK10 Antikörper (ABIN359899) Bilder zurück nach oben
Applikations-hinweise ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-MCK10 Antikörper Target Details MCK10 Anwendungsinformationen Referenzen für anti-MCK10 Antikörper (ABIN359899) Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen für anti-MCK10 Antikörper (ABIN359899)

Produktdetails anti-MCK10 Antikörper Target Details MCK10 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Vogel, Gish, Alves, Pawson: "The discoidin domain receptor tyrosine kinases are activated by collagen." in: Molecular cell, Vol. 1, Issue 1, pp. 13-23, 1998

Ghauri, Chapman, Meldrum: "Convulsant and anticonvulsant actions of agonists and antagonists of group III mGluRs." in: Neuroreport, Vol. 7, Issue 9, pp. 1469-74, 1997

Playford, Butler, Wang, Katso, Cooke, Ganesan: "The genomic structure of discoidin receptor tyrosine kinase." in: Genome research, Vol. 6, Issue 7, pp. 620-7, 1996

Valent, Meddeb, Danglot, Duverger, Nguyen, Bernheim: "Assignment of the NTRK4 (trkE) gene to chromosome 6p21." in: Human genetics, Vol. 98, Issue 1, pp. 12-5, 1996

Edelhoff, Sweetser, Disteche: "Mapping of the NEP receptor tyrosine kinase gene to human chromosome 6p21.3 and mouse chromosome 17C." in: Genomics, Vol. 25, Issue 1, pp. 309-11, 1995

Bilder

Produktdetails anti-MCK10 Antikörper Target Details MCK10 Anwendungsinformationen Handhabung Referenzen für anti-MCK10 Antikörper (ABIN359899) zurück nach oben
Bilder des Herstellers
 image for anti-Discoidin Domain Receptor Family, Member 1 (DDR1) antibody (ABIN359899) anti-Discoidin Domain Receptor Family, Member 1 (DDR1) antibody
 image for anti-Discoidin Domain Receptor Family, Member 1 (DDR1) antibody (ABIN359899) anti-Discoidin Domain Receptor Family, Member 1 (DDR1) antibody (Image 2)