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anti-Human KIT Antikörper:
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combined panel had the highest sensitivity and specificity at 96.3% and 100%, which was significantly or marginally higher than those of EZH2 (zeige EZH2 Antikörper), C-KIT, and CD205 (zeige LY75 Antikörper) alone
current c-Kit reporter models are discussed with respect to myocardial c-Kit cell biology and function.
PKC-delta (zeige PKCd Antikörper) expression is associated with KIT expression and the prognosis of patients with adenoid cystic carcinomas (AdCCs), suggesting that PKC-delta (zeige PKCd Antikörper) may be a potential therapeutic target for AdCCs.
Study demonstrates that an oncogenic tyrosine kinase (zeige TXK Antikörper) mutant, KIT(D816V), can alter the transcriptional program of the transcription factor MITF (zeige MITF Antikörper) in melanoma.
High c-kit expression is associated with small cell lung cancer.
The expression of c-Kit under the influence of nilotinib, dasatinib, erlotinib, gefitinib and afatinib was studied in HPV-positive head and neck squamous cell carcinomas. Gefitinib significantly increased cKIT expression in HPV-positive and HPV-negative head and neck squamous cell carcinoma cells whereas nilotinib and afatinib decreased cKIT expression in HPV-positive SCC (zeige CYP11A1 Antikörper).
Our findings showed that increased expression of CD34 (zeige CD34 Antikörper) and CD117 markers confer tumor progression and aggressiveness on prostate cancer.
A phase Ib study of dasatinib plus ipilimumab in patients with gastrointestinal stromal tumor (GIST) and other sarcomas was performed on the basis of preclinical data demonstrating that combined KIT and CTLA-4 (zeige CTLA4 Antikörper) blockade is synergistic.
4 different mutant (MT-KIT) KIT proteins from GIST tumors are intrinsically less stable than wild-type KIT due to proteasome-mediated degradation and abnormally localized to the endoplasmic reticulum or the Golgi complex. PKC-theta (zeige PRKCQ Antikörper); is strongly and exclusively expressed in GISTs and interacts with intracellular MT-KIT to promote its stabilization by increased retention in the Golgi complex.
Report a new in vivo model of KIT D816V+ advanced systemic mastocytosis developed by transplantation of the human ROSAKIT D816V-Gluc (zeige GBA Antikörper) mast cell line in NOD-SCID (zeige PRKDC Antikörper) IL-2R gamma (zeige IL2RG Antikörper)-/- mice, using Gaussia princeps luciferase as a reporter.
FGF7 (zeige FGF7 Antikörper) may be an important regulator for oocyte growth and its action is mediated via the KIT/KITLG (zeige KITLG Antikörper) signaling pathway.
These results suggest that DDX4 (zeige DDX4 Antikörper) and c-kit are putative markers of undifferentiated spermatogonia in the prepubertal porcine testis.
mRNA expression of c-kit and SCF was decreased in gallbladder tissues in the HCD group. Consistent with the findings of RT-PCR, a lower expression level of c-kit and SCF protein was also observed in HCD animals.
Delayed enrichment for c-kit and inducing cardiac differentiation attenuated protective effects of BMSCs' transplantation in pig model of acute myocardial infarction.
Pravastatin improves function in hibernating myocardium by mobilizing CD133+ and cKit+ bone marrow progenitor cells and promoting myocytes to reenter the growth phase of the cardiac cell cycle.
PAX3 (zeige PAX3 Antikörper) gene and sabino1 of KIT gene interact to create different coat color patterns
the missense mutation p.Arg682His, the g.77784972T>C variant at KIT and the g.20147039C>T variant at MITF (zeige MITF Antikörper) are the main influence on the extent of white facial markings
Accumulating mutations in series of haplotypes at the KIT and MITF (zeige MITF Antikörper) loci are major determinants of white markings in Franches-Montagnes horses.
c-kit is primarily expressed in the spermatogonia and spermatocytes of goat testes.
The expression of c-kit and beta-catenin (zeige CTNNB1 Antikörper) suggests that erythropoietin (zeige EPO Antikörper) may exert a role in regeneration reducing the extent of tubular damage from the outset after gentamicin administration.
The role of ErbB (zeige EGFR Antikörper) and Kit signalling in establishing melanophore stem cells in zebrafish.
The regeneration defect in kita mutants is not due to defects in melanocyte stem cells recruitment or in the proliferation, differentiation or survival of the daughter cells, but is instead due to a defect in stem cell establishment.
Kita driven expression of oncogenic HRAS (zeige HRAS Antikörper) leads to early onset and highly penetrant melanoma in zebrafish
Ectopic expression of foxd3 (zeige FOXD3 Antikörper) indicates that foxd3 (zeige FOXD3 Antikörper) promotes early melanophore death only when kit is inactive
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
mast/stem cell growth factor receptor Kit
, p145 c-kit
, piebald trait protein
, proto-oncogene c-Kit
, proto-oncogene tyrosine-protein kinase Kit
, soluble KIT variant 1
, tyrosine-protein kinase Kit
, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
, c-kit-related protein
, kit-related kinase 1
, mast/stem cell growth factor receptor-related protein Kit
, proto-oncogene tyrosine-protein kinase Kit-related protein
, Mast/stem cell growth factor receptor
, c-kit receptor tyrosine kinase
, mast/stem cell growth factor receptor
, protein kinase
, c-kit receptor
, mast cell growth factor receptor
, c-KIT gene1
, receptor tyrosine kinase c-kit
, tyrosine kinase receptor homolog
, transmembrane tyrosine kinase receptor
, Proto-oncogene c-Kit
, Tyrosine-protein kinase Kit
, caprine c-kit protein
, c-kit homolog
, mast/stem cell growth factor receptor kita
, tyrosine kinase