anti-Human HER2 Antikörper für Dot Blot

Recommended HER2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antikörper
  • CD340
  • HER-2
  • HER-2/neu
  • HER2
  • MLN 19
  • NEU
  • NGL
  • TKR1
  • Erbb-2
  • Neu
  • c-erbB2
  • c-neu
  • mKIAA3023
  • wu:fv70f10
  • zgc:63601
  • erb2
  • erb-b2 receptor tyrosine kinase 2
  • ERBB2
  • Erbb2
  • erbb2
Epitop
pTyr1248
130
86
67
67
58
44
31
29
27
25
24
22
22
15
14
13
13
12
12
11
11
11
11
10
10
10
10
10
10
10
9
9
8
7
7
7
6
6
5
5
5
5
5
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
1235
384
296
31
21
10
6
6
6
4
4
3
3
3
3
3
2
2
2
2
1
1
1
Wirt
Kaninchen
730
569
22
16
8
3
3
Klonalität
Polyklonal
Konjugat
Dieser HER2 Antikörper ist unkonjugiert
55
44
42
41
40
27
16
16
11
10
10
9
9
8
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
5
2
2
1
Applikation
Dot Blot (DB), Western Blotting (WB)
637
451
403
400
342
189
186
96
96
83
80
47
24
21
18
8
6
3
3
3
2
1
1
1
1
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN1881305
$ 385.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
25.369835 ABIN1881312 DB IF WB Rabbit pTyr1005 Anmelden zum Anzeigen Polyclonal 3
25.369835 ABIN1881313 DB IF WB Rabbit pTyr1196 Anmelden zum Anzeigen Polyclonal 3
22.369835 ABIN1881304 DB WB Rabbit pTyr1112 Anmelden zum Anzeigen Polyclonal 5
22.369835 ABIN1881408 DB WB Rabbit pTyr1112 Anmelden zum Anzeigen Polyclonal 5
20.869835 ABIN3029498 DB IF ELISA WB Rabbit Ig Fraction pTyr1005 Anmelden zum Anzeigen Polyclonal 0
20.869835 ABIN3029502 DB ELISA WB Rabbit Ig Fraction pTyr1140 Anmelden zum Anzeigen Polyclonal 0
20.869835 ABIN3029500 DB IF ELISA WB Rabbit Ig Fraction pTyr1127 Anmelden zum Anzeigen Polyclonal 0
20.869835 ABIN3029493 DB IF ELISA WB Rabbit Ig Fraction pTyr1196 Anmelden zum Anzeigen Polyclonal 0
20.869835 ABIN2970949 DB WB Rabbit IgG pTyr1248 Anmelden zum Anzeigen Polyclonal 0
20.869835 ABIN3001988 DB WB Rabbit IgG pTyr877 Anmelden zum Anzeigen Polyclonal 0
20.869835 ABIN3001991 DB IF/ICC WB Rabbit IgG pTyr1005 Anmelden zum Anzeigen Polyclonal 0
20.869835 ABIN3001992 DB IF/ICC WB Rabbit IgG pTyr1196 Anmelden zum Anzeigen Polyclonal 0
20.869835 ABIN3001985 DB IF/ICC WB Rabbit IgG pTyr1127 Anmelden zum Anzeigen Polyclonal 0
17.869835 ABIN1539754 DB WB Rabbit Ig pTyr877 Anmelden zum Anzeigen Polyclonal 0
17.869835 ABIN1539721 DB IF Rabbit Ig pThr1172 Anmelden zum Anzeigen Polyclonal 0
17.869835 ABIN1539720 DB IF Rabbit Ig pThr1166 Anmelden zum Anzeigen Polyclonal 0
17.869835 ABIN1539738 DB WB Rabbit Ig pTyr1139 Anmelden zum Anzeigen Polyclonal 0
17.869835 ABIN1539689 DB WB Rabbit Ig pSer1151 Anmelden zum Anzeigen Polyclonal 0
17.869835 ABIN1539785 DB IF WB Rabbit Ig pTyr1127 Anmelden zum Anzeigen Polyclonal 0
17.869835 ABIN3029497 DB IF ELISA Rabbit Ig Fraction pThr1172 Anmelden zum Anzeigen Polyclonal 0

General

Antigen V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antikörper
Epitop pTyr1248
(130), (86), (67), (67), (58), (44), (31), (29), (27), (25), (24), (22), (22), (15), (14), (13), (13), (12), (12), (11), (11), (11), (11), (10), (10), (10), (10), (10), (10), (10), (9), (9), (8), (7), (7), (7), (6), (6), (5), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(1235), (384), (296), (31), (21), (10), (6), (6), (6), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1)
Wirt Kaninchen
(730), (569), (22), (16), (8), (3), (3)
Klonalität (Klon)
Polyklonal   ( )
Konjugat Dieser HER2 Antikörper ist unkonjugiert
(55), (44), (42), (41), (40), (27), (16), (16), (11), (10), (10), (9), (9), (8), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (2), (2), (1)
Applikation Dot Blot (DB), Western Blotting (WB)
(637), (451), (403), (400), (342), (189), (186), (96), (96), (83), (80), (47), (24), (21), (18), (8), (6), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-HER2 Antikörper

Target Details HER2 Anwendungsinformationen Handhabung Referenzen für anti-HER2 Antikörper (ABIN1881305) Bilder
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This ErbB2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1248 of human ErbB2.
Klon RB40739
Plasmids, Primers & others

Target Details HER2

Produktdetails anti-HER2 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-HER2 Antikörper (ABIN1881305) Bilder zurück nach oben
Antigen
Andere Bezeichnung ERBB2 (ERBB2 Antibody Abstract)
Hintergrund ErbB2 is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors.

Synonyms: Receptor tyrosine-protein kinase erbB-2 [Precursor], p185erbB2, C-erbB-2, NEU proto-oncogene, Tyrosine kinase-type cell surface receptor HER2, MLN 19, ERBB2, HER2, NEU, NGL,
NCBI Accession NP_001005862, NP_004439
UniProt P04626
Pathways RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development

Anwendungsinformationen

Produktdetails anti-HER2 Antikörper Target Details HER2 Handhabung Referenzen für anti-HER2 Antikörper (ABIN1881305) Bilder zurück nach oben
Applikations-hinweise WB: 1:8000,DB: 1:500
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-HER2 Antikörper Target Details HER2 Anwendungsinformationen Referenzen für anti-HER2 Antikörper (ABIN1881305) Bilder zurück nach oben
Format Liquid
Konzentration 0.32 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Referenzen für anti-HER2 Antikörper (ABIN1881305)

Produktdetails anti-HER2 Antikörper Target Details HER2 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Brandt, Mikesch, Simon, Rötger, Kemming, Schier, Sauter, Bürger: "Selective expression of a splice variant of decay-accelerating factor in c-erbB-2-positive mammary carcinoma cells showing increased transendothelial invasiveness." in: Biochemical and biophysical research communications, Vol. 329, Issue 1, pp. 318-23, 2005

Ghatak, Misra, Toole: "Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells." in: The Journal of biological chemistry, Vol. 280, Issue 10, pp. 8875-83, 2005

Provinciali, Re, Donnini, Orlando, Bartozzi, Di Stasio, Smorlesi: "Effect of resveratrol on the development of spontaneous mammary tumors in HER-2/neu transgenic mice." in: International journal of cancer. Journal international du cancer, Vol. 115, Issue 1, pp. 36-45, 2005

Yee, Young, Rosol, Vanbuskirk, Clinton: "Dietary (n-3) polyunsaturated fatty acids inhibit HER-2/neu-induced breast cancer in mice independently of the PPARgamma ligand rosiglitazone." in: The Journal of nutrition, Vol. 135, Issue 5, pp. 983-8, 2005

Beckers, Herrmann, Rieger, Drobyshev, Horsch, Hrabé de Angelis, Seliger: "Identification and validation of novel ERBB2 (HER2, NEU) targets including genes involved in angiogenesis." in: International journal of cancer. Journal international du cancer, Vol. 114, Issue 4, pp. 590-7, 2005

Bilder

Produktdetails anti-HER2 Antikörper Target Details HER2 Anwendungsinformationen Handhabung Referenzen für anti-HER2 Antikörper (ABIN1881305) zurück nach oben
Bilder des Herstellers
Dot Blot (DB) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr1248) antibody (ABIN1881305) Dot blot analysis of anti-Phospho-ErbB2-pY1248(M) Phospho-specific Pab (ABIN1881305) ...
Western Blotting (WB) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr1248) antibody (ABIN1881305) Dot blot analysis of anti-Phospho-ErbB2-pY1248(M) Phospho-specific Pab (ABIN1881305) ...
Western Blotting (WB) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr1248) antibody (ABIN1881305) Dot blot analysis of anti-Phospho-ErbB2-pY1248(M) Phospho-specific Pab (ABIN1881305) ...