anti-Human GDNF Antikörper für Functional Studies

Recommended GDNF Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Glial Cell Line Derived Neurotrophic Factor (GDNF) Antikörper
  • gdnf
  • GDNF
  • AI385739
  • gdnfa
  • hfb1-gdnf
  • ATF1
  • ATF2
  • HFB1-GDNF
  • HSCR3
  • glial cell derived neurotrophic factor
  • glial cell derived neurotrophic factor a
  • glial cell line derived neurotrophic factor
  • glial cell derived neurotrophic factor L homeolog
  • Gdnf
  • gdnfa
  • GDNF
  • gdnf.L
Reaktivität
Human
167
78
58
1
Wirt
Kaninchen
152
22
9
4
2
Klonalität
Polyklonal
Konjugat
Dieser GDNF Antikörper ist unkonjugiert
19
11
7
5
5
5
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
174
49
39
28
27
21
13
13
13
5
5
4
3
2
1
1
1
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN116022
$ 368.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN116021 EIA Func IHC (fro) WB Rabbit Anmelden zum Anzeigen Polyclonal 0

General

Antigen Glial Cell Line Derived Neurotrophic Factor (GDNF) Antikörper
Reaktivität Human
(167), (78), (58), (1)
Wirt Kaninchen
(152), (22), (9), (4), (2)
Klonalität
Polyklonal
Konjugat Dieser GDNF Antikörper ist unkonjugiert
(19), (11), (7), (5), (5), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(174), (49), (39), (28), (27), (21), (13), (13), (13), (5), (5), (4), (3), (2), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-GDNF Antikörper

Target Details GDNF Anwendungsinformationen Handhabung Bilder
Spezifität This antibody is Specific for Human Glial Derived Neurotrophic Factor (GDNF).
Reinigung Affinity chromatography.
Immunogen Highly pure (>98%) recombinant hGDNF.
Plasmids, Primers & others

Target Details GDNF

Produktdetails anti-GDNF Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung GDNF (GDNF Antibody Abstract)
Hintergrund Glial cell line derived neurotrophic factor (GDNF) is a highly conserved neurotrophic factor that is a distant member of the TGF beta superfamily. The GDNF gene product is processed to a disulphide-linked homodimer, which is a ligand for the RET protooncogene. GDNF protects and repairs dopamine-containing neurons, which degenerate in Parkinson's disease, and motor neurons, which die in amyotrophic lateral sclerosis. The use of GDNF in the treatment of Parkinson's disease has shown promise in the clinic. Treatment of spinal cord injuries with GDNF has also produced neurological improvement.Synonyms: ATF, Astrocyte-derived trophic factor, Glial cell line-derived neurotrophic factor
Gen-ID 2668
NCBI Accession NP_000505
UniProt P39905
Pathways RTK Signalweg, Synaptic Membrane, Tube Formation, Autophagie, Smooth Muscle Cell Migration

Anwendungsinformationen

Produktdetails anti-GDNF Antikörper Target Details GDNF Handhabung Bilder zurück nach oben
Applikations-hinweise Neutralization. ELISA: (Indirect): To detect hGDNF by indirect ELISA (using 100 μL/well antibody solution) aconcentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with compatible secondary reagents, allows the detection of atleast 0.2-0.4 ng/well of recombinant hGDNF. (Sandwich): To detect hGDNF by sandwich ELISA (using 100 μL/well antibody solution) aconcentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with Biotinylated Anti-Human GDNF (PP1010B) as a detectionantibody, allows the detection of at least 0.2-0.4 ng/well of recombinant hGDNF. Western Blot: To detect hGDNF by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hGDNF is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-GDNF Antikörper Target Details GDNF Anwendungsinformationen Bilder zurück nach oben
Rekonstitution Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
Buffer PBS, pH 7.2 without preservatives.
Konservierungs-mittel Without preservative
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.