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Human FGF2 Protein expressed in Escherichia coli (E. coli) - ABIN803891
Robinson, Zhao, Rathjen, Rathjen, Hutchinson, Eyre, Hemsley, Hopwood: Embryonic stem cell-derived glial precursors as a vehicle for sulfamidase production in the MPS-IIIA mouse brain. in Cell transplantation 2010
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Human FGF2 Protein expressed in Escherichia coli (E. coli) - ABIN2721053
Li, Zuo, Jing, Ma, Wang, Liu, Zhu, Du, Xiong, Du, Xu, Xiao, Wang, Chai, Zhao, Deng: Small-Molecule-Driven Direct Reprogramming of Mouse Fibroblasts into Functional Neurons. in Cell stem cell 2015
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Human FGF2 Protein expressed in Escherichia coli (E. coli) - ABIN413246
Matsukura, Muneta, Tsuji, Miyatake, Yamada, Abula, Koga, Tomita, Sekiya: Mouse synovial mesenchymal stem cells increase in yield with knee inflammation. in Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2014
Human FGF2 Protein expressed in Escherichia coli (E. coli) - ABIN2129216
Czekanska, Ralphs, Alini, Stoddart: Enhancing inflammatory and chemotactic signals to regulate bone regeneration. in European cells & materials 2014
Human FGF2 Protein expressed in Escherichia coli (E. coli) - ABIN2001904
Wied?ocha, Falnes, Madshus, Sandvig, Olsnes: Dual mode of signal transduction by externally added acidic fibroblast growth factor. in Cell 1994
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Human FGF2 Protein expressed in - ABIN621679
Guan, Guo, Yu, Wang, Wang, Konstantopoulos, Wang, Wang: The role of cyclooxygenase-2, interleukin-1β and fibroblast growth factor-2 in the activation of matrix metalloproteinase-1 in sheared-chondrocytes and articular cartilage. in Scientific reports 2015
BMP4 (zeige BMP4 Proteine) promotes survival of neural stem/progenitor cells by enhancing the anti-apoptotic function of Bcl-xL (zeige BCL2L1 Proteine) via BMP4 (zeige BMP4 Proteine)-Smad1 (zeige SMAD1 Proteine)/5/8-Id1 (zeige ID1 Proteine) signaling in the presence of FGF-2.
FGF2 signaling can regulate osteoblastic niche cells to support HSC (zeige FUT1 Proteine) homeostasis in response to bone marrow damage
Dynamic changes in heparan sulfate during muscle differentiation and ageing regulate myoblast cell fate and FGF2 signaling.
altered glycosaminoglycans (GAG) distribution in mucopolysaccharidoses I (MPS I) chondrocytes, and altered GAG, FGF2 and Indian hedgehog (zeige IHH Proteine) distribution in growth plates from MPS I mice, is reported.
Data show that LOX (zeige LOX Proteine)-PP enhances adipogenesis at least partially through inhibition of FGF-2 receptor signaling.
tissue engineered periosteum can deliver FGF-2, TGF-beta1 (zeige TGFB1 Proteine), and ASCs to a mouse critical-sized femur defect and further optimization may yield improved bone allograft healing.
Thus, FGF-2 levels in hESCs culture systems can be manipulated to generate cells with longer telomere which would be advantageous in the applications of hESCs in regenerative medicine.
Low FGF2 expression is associated with cardiac ischemia and systolic dysfunction.
Mechanical strain stimulates vasculogenesis of embryonic stem cells by the intracellular messengers ROS (zeige ROS1 Proteine), NO and calcium as well as by upregulation of angiogenesis guidance molecules and the angiogenic growth factors VEGF (zeige VEGFA Proteine), FGF-2 and PDGF (zeige PDGFA Proteine)-BB.
FGFR (zeige FGFR2 Proteine) Inhibitor Ameliorates Hypophosphatemia and Impaired Engrailed-1/Wnt (zeige WNT2 Proteine) Signaling in FGF2 High Molecular Weight Isoform
Results uncover a novel Sdc2 (zeige SDC2 Proteine)-Tbx16-Fgf2 pathway that regulates epithelial cell morphogenesis.
activation of FGFR1 (zeige FGFR1 Proteine) and FGFR2 (zeige FGFR2 Proteine) by uterine- and endometrial-derived FGF2 stimulates PI3K/AKT (zeige AKT1 Proteine) and mitogen-activated protein kinase (zeige MAPK1 Proteine) pathways for development of the porcine uterus and improvement of litter size
Taken together, Staphylococcus aureus induces TGF-beta1 (zeige TGFB1 Proteine) and bFGF expression through the activation of AP-1 (zeige JUN Proteine) and NF-kappaB (zeige NFKB1 Proteine) in bovine mammary gland fibroblasts.
Data suggest THBS1 (thrombospondin-1 (zeige THBS1 Proteine)) expression predominates in luteal endothelial cells; THBS2 (zeige THBS2 Proteine) expression predominates in luteinized granulosa cells. Luteinizing signals down-regulate expression of THBS1 (zeige THBS1 Proteine)/THBS2 (zeige THBS2 Proteine) but up-regulate expression of FGF2.
Mixed populations of luteal cells were treated with SU1498 (VEGF receptor 2 inhibitor) or SU5402 (FGF receptor 1 inhibitor) or control on days 0-3, 3-6 or 6-9 to determine the role of FGF2 and VEGFA (zeige VEGFA Proteine) during these specific windows.
FGF2 was crucial for luteal endothelial network formation.
Associations between reproduction and milk traits, and polymorphisms at the STAT5A (zeige STAT5A Proteine) and FGF2 gene loci, were found with STAT5A (zeige STAT5A Proteine) polymorphism for age at first calving (suggestive effect; P =0.077) and lactation milk yield (significant effect; P<0.05).
FGF2 and FGF10 (zeige FGF10 Proteine) regulate migratory activity of ovine trophoblast cells through MAPK (zeige MAPK1 Proteine)-dependent pathways.
investigation of signaling mechanisms used by FGF2 to regulate interferon-tau (IFNT) production in trophoblasts: several lines of evidence suggest that FGF2 regulates IFNT production in trophoblasts by acting through protein kinase C-delta (zeige PKCd Proteine)
Alterations in the expression of VEGF-A (zeige VEGFA Proteine) and bFGF systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.
bFGF is oxidized by lysyl oxidase (zeige LOX Proteine)
Dysregulation of the FGF2 gene represents an opportunity to understand further, and possibly intervene upon, mechanisms of wound healing in diabetics with CKD.
Out of five FGF-2 Gene Polymorphism loci, the TA genotype of rs308442 in the osteoporosis group (40.2%) was higher than in the control group (29.5%) (p < 0.05). The rs308442 locus of FGF-2 gene is closely correlated to osteoporosis in this Zhuang ethnic Chinese cohort, and the TA may be the risk genotype of osteoporosis.
Up-regulation of FGF2 and down-regulation FAM201A were correlated with the development of osteonecrosis of the femoral head after femoral neck fracture.
over-expression, isolation, and biological activity of all recombinant human FGF2 isoforms, are reported.
We found that hsa (zeige CD24 Proteine)-miR (zeige MLXIP Proteine)-196a-3p affected expression on both mRNA and protein levels of FGF2. our study provided evidence that a functional SNP rs1048201 was associated with bone mineral density (BMD (zeige BEST1 Proteine)), and SNP rs1048201 variant may act by affecting binding of hsa (zeige CD24 Proteine)-miR (zeige MLXIP Proteine)-196a-3p
Data show that mutant soluble ectodomain of FGFR2IIIc (msFGFR2c) but not wild-type soluble ectodomain of FGFR2IIIc (wsFGFR2c) could selectively bind to c subtype of FGFRs in the presence of FGF-2.
Furthermore, MERS coronavirus induced apoptosis through upregulation of Smad7 (zeige SMAD7 Proteine) and fibroblast growth factor 2 (FGF2) expression in both kidney and lung cells.
The present work aims to investigate the relationship between the expression of AEG-1 (zeige MTDH Proteine)(astrocyte elevated gene-1), b-FGF(basic-fibroblast growth factor), beta-catenin (zeige CTNNB1 Proteine), Ki-67 (zeige MKI67 Proteine), TNF-alpha (tumor necrosis factor (zeige TNF Proteine)-alfa) other prognostic parameters in DC (Ductal Carcinomas) and ductal intraepithelial neoplasm. We found a relationship between these factors.
Studies indicate that therapeutically targeting FGF2 and FGFR (zeige FGFR2 Proteine) has been extensively assessed in multiple preclinical studies and numerous drugs and treatment options have been tested in clinical trials.
FGF2 is involved in melanoma development and progression. HMW FGF2 isoforms enhance in vitro motility of melanoma cells. LMW FGF2 confers stem-like features and increases in vivo metastasization. LMW FGF2 promotes angiogenesis while HMW FGF2 induces vasculogenic mimicry.
Continuous passive motion can promote b-FGF expression to enhance type III collagen (zeige COL3A1 Proteine) synthesis at the tendon-bone interface in early stage of tendon-bone repair following acute rupture of supraspinatus tendon in rabbits.
Fibroblast growth factor-2 promotes in vitro heart valve interstitial cell repair through the Akt1 (zeige AKT1 Proteine) pathway.
The overlapping relationships of 3'UTR ends between NUDT6 (zeige NUDT6 Proteine) and FGF-2 genes, were analyzed.
FGF2 in porcine ovary may be important for the growth of more follicles due to the localisation and concentration difference between stroma and follicle tissue.
By inducing the release of an endothelial elastase, shear stress induces an integrin-dependent release of FGF-2 from endothelial cells.
qPCR analysis demonstrated an increase in FGF-2 mRNA levels beginning on day 75 and on day 114 of pregnancy.
FGF2 activates FGFR (zeige FGFR2 Proteine) which then represses the fibroblast activation of valvular interstitial cells.
FGF2 effectively blocks transforming growth factor-beta1 (TGF-beta1 (zeige TGFB1 Proteine))-mediated myofibroblast activation
upregulation of TGFalpha or FGF2 expression is not a pre-requisite for enhanced testicular growth and increased Sertoli cell proliferation that occurs subsequent to hemicastration in the neonatal boar
These results suggest that bFGF activation of neuronal FGFR1 (zeige FGFR1 Proteine) generates filopodial processes in neurons that promote nerve-muscle interaction and facilitate NMJ establishment.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
, basic fibroblast growth factor
, heparin-binding growth factor 2
, fibroblast growth factor 2
, basic fibroblast growth factor bFGF
, Basic fibroblast growth factor
, Heparin-binding growth factor 2