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Human FGF2 Protein expressed in Escherichia coli (E. coli) - ABIN2721053
Li, Zuo, Jing, Ma, Wang, Liu, Zhu, Du, Xiong, Du, Xu, Xiao, Wang, Chai, Zhao, Deng: Small-Molecule-Driven Direct Reprogramming of Mouse Fibroblasts into Functional Neurons. in Cell stem cell 2015
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Human FGF2 Protein expressed in Escherichia coli (E. coli) - ABIN803891
Robinson, Zhao, Rathjen, Rathjen, Hutchinson, Eyre, Hemsley, Hopwood: Embryonic stem cell-derived glial precursors as a vehicle for sulfamidase production in the MPS-IIIA mouse brain. in Cell transplantation 2010
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Human FGF2 Protein expressed in Escherichia coli (E. coli) - ABIN2001904
Wied?ocha, Falnes, Madshus, Sandvig, Olsnes: Dual mode of signal transduction by externally added acidic fibroblast growth factor. in Cell 1994
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Human FGF2 Protein expressed in Escherichia coli (E. coli) - ABIN2129216
Czekanska, Ralphs, Alini, Stoddart: Enhancing inflammatory and chemotactic signals to regulate bone regeneration. in European cells & materials 2014
Human FGF2 Protein expressed in Escherichia coli (E. coli) - ABIN413246
Matsukura, Muneta, Tsuji, Miyatake, Yamada, Abula, Koga, Tomita, Sekiya: Mouse synovial mesenchymal stem cells increase in yield with knee inflammation. in Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2014
Human FGF2 Protein expressed in - ABIN621679
Guan, Guo, Yu, Wang, Wang, Konstantopoulos, Wang, Wang: The role of cyclooxygenase-2, interleukin-1β and fibroblast growth factor-2 in the activation of matrix metalloproteinase-1 in sheared-chondrocytes and articular cartilage. in Scientific reports 2015
the dual warhead-FGF2 conjugate may overcome the potential acquired resistance of FGFR1 (zeige FGFR1 Proteine)-overproducing cancer cells towards single cytotoxic drugs.
FGF2 initiates CYGB (zeige CYGB Proteine) transcription via the JNK (zeige MAPK8 Proteine) pathway.
A strong stromal FGF-2 expression was associated with a significantly higher clinical stage and higher biochemical recurrence rate. Patients with strong stromal FGF-2 expression also had a significantly worse biochemical recurrence-free survival.
levels of the angiogenesis mediators endoglin (zeige ENG Proteine), HB-EGF (zeige HBEGF Proteine), BMP-9 (zeige GDF2 Proteine) and FGF-2 in patients with severe sepsis and septic shock
Our results suggest photodynamic therapy is effective in increasing the expression of bFGF gene, an important factor in periodontal tissue regeneration and could indicate periodontal tissue regeneration
High FGF2 expression is associated with gastric cancer.
Regulation of vascular smooth muscle cell calcification by syndecan-4 (zeige SDC4 Proteine)/FGF-2/PKCalpha (zeige PKCa Proteine) signalling and cross-talk with TGF-beta1 (zeige TGFB1 Proteine).
evaluation of the presence and localization of FGF2 in human sperm cells, and determination of FGF2 levels in semen samples and its relationship with conventional semen parameters
We have presented evidence that FGF2 promotes myofibroblast apoptosis in vivo, antagonizes pro-fibrotic TGF-beta (zeige TGFB1 Proteine) signaling, inhibits fibroblast activation and prevents transdifferentiation of non-fibroblasts into myofibroblasts, and promotes a less fibrotic gene expression paradigm [Review]
These results demonstrate that FGF-TGFbeta (zeige TGFB1 Proteine) signaling antagonism is the primary regulator of the smooth muscle cell phenotype switch.
present study highlights the central role for FGF-2 in the progression and maintenance of newly acquired blood and lymphatic vessels in the cornea of HSV-1-infected mice in the absence of infectious virions
NF-kappaBmiR15abFGF/VEGFA (zeige VEGFA Proteine) axis contributes to the impaired angiogenic capacity of bone marrowmesenchymal stem cells in high fat dietfed mice.
Fibroblast growth factor (FGF1 (zeige FGF1 Proteine) and FGF2), but not vascular endothelial growth factor (VEGF (zeige VEGF Proteine)) rescued Psen1 (zeige PSEN1 Proteine)-/- cells from serum starvation induced apoptosis.In the absence of serum, FGF2 immunoreactivity was distributed diffusely in cytoplasmic and nuclear vesicles of wt and Psen1 (zeige PSEN1 Proteine)-/- cells, as levels of FGF2 in nuclear and cytosolic fractions were not significantly different.
Knockout of the 18-kDa FGF-2 isoform significantly attenuated atherogenesis, reduced aortic plaques, reduced macrophage infiltration and suppressed oxidative stress in mice fed with a high fat diet at all-time points.
Data show that exostosin-like 2 (EXTL2 (zeige EXTL2 Proteine)) controls fibroblast growth factor 2 (FGF2) signaling through regulation of heparan sulfate biosynthesis.
BMP4 (zeige BMP4 Proteine) promotes survival of neural stem/progenitor cells by enhancing the anti-apoptotic function of Bcl-xL (zeige BCL2L1 Proteine) via BMP4 (zeige BMP4 Proteine)-Smad1 (zeige SMAD1 Proteine)/5/8-Id1 (zeige ID1 Proteine) signaling in the presence of FGF-2.
FGF2 signaling can regulate osteoblastic niche cells to support HSC (zeige FUT1 Proteine) homeostasis in response to bone marrow damage
Dynamic changes in heparan sulfate during muscle differentiation and ageing regulate myoblast cell fate and FGF2 signaling.
altered glycosaminoglycans (GAG) distribution in mucopolysaccharidoses I (MPS I) chondrocytes, and altered GAG, FGF2 and Indian hedgehog (zeige IHH Proteine) distribution in growth plates from MPS I mice, is reported.
Data show that LOX (zeige LOX Proteine)-PP enhances adipogenesis at least partially through inhibition of FGF-2 receptor signaling.
These results suggest that bFGF activation of neuronal FGFR1 (zeige FGFR1 Proteine) generates filopodial processes in neurons that promote nerve-muscle interaction and facilitate NMJ establishment.
activation of FGFR1 (zeige FGFR1 Proteine) and FGFR2 (zeige FGFR2 Proteine) by uterine- and endometrial-derived FGF2 stimulates PI3K/AKT (zeige AKT1 Proteine) and mitogen-activated protein kinase (zeige MAPK1 Proteine) pathways for development of the porcine uterus and improvement of litter size
Taken together, Staphylococcus aureus induces TGF-beta1 (zeige TGFB1 Proteine) and bFGF expression through the activation of AP-1 (zeige JUN Proteine) and NF-kappaB (zeige NFKB1 Proteine) in bovine mammary gland fibroblasts.
Data suggest THBS1 (thrombospondin-1 (zeige THBS1 Proteine)) expression predominates in luteal endothelial cells; THBS2 (zeige THBS2 Proteine) expression predominates in luteinized granulosa cells. Luteinizing signals down-regulate expression of THBS1 (zeige THBS1 Proteine)/THBS2 (zeige THBS2 Proteine) but up-regulate expression of FGF2.
Mixed populations of luteal cells were treated with SU1498 (VEGF receptor 2 inhibitor) or SU5402 (FGF receptor 1 inhibitor) or control on days 0-3, 3-6 or 6-9 to determine the role of FGF2 and VEGFA (zeige VEGFA Proteine) during these specific windows.
FGF2 was crucial for luteal endothelial network formation.
Associations between reproduction and milk traits, and polymorphisms at the STAT5A (zeige STAT5A Proteine) and FGF2 gene loci, were found with STAT5A (zeige STAT5A Proteine) polymorphism for age at first calving (suggestive effect; P =0.077) and lactation milk yield (significant effect; P<0.05).
FGF2 and FGF10 (zeige FGF10 Proteine) regulate migratory activity of ovine trophoblast cells through MAPK (zeige MAPK1 Proteine)-dependent pathways.
investigation of signaling mechanisms used by FGF2 to regulate interferon-tau (IFNT) production in trophoblasts: several lines of evidence suggest that FGF2 regulates IFNT production in trophoblasts by acting through protein kinase C-delta (zeige PKCd Proteine)
Alterations in the expression of VEGF-A (zeige VEGFA Proteine) and bFGF systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.
bFGF is oxidized by lysyl oxidase (zeige LOX Proteine)
FOXO1 (zeige FOXO1 Proteine)-suppressed miR (zeige MYLIP Proteine)-424 regulates both the proliferation and osteogenic differentiation of mesenchymal stem cells via targeting FGF2.
Fibroblast growth factor-2 promotes in vitro heart valve interstitial cell repair through the Akt1 (zeige AKT1 Proteine) pathway.
The overlapping relationships of 3'UTR ends between NUDT6 (zeige NUDT6 Proteine) and FGF-2 genes, were analyzed.
FGF2 in porcine ovary may be important for the growth of more follicles due to the localisation and concentration difference between stroma and follicle tissue.
By inducing the release of an endothelial elastase, shear stress induces an integrin-dependent release of FGF-2 from endothelial cells.
qPCR analysis demonstrated an increase in FGF-2 mRNA levels beginning on day 75 and on day 114 of pregnancy.
FGF2 activates FGFR (zeige FGFR2 Proteine) which then represses the fibroblast activation of valvular interstitial cells.
FGF2 effectively blocks transforming growth factor-beta1 (TGF-beta1 (zeige TGFB1 Proteine))-mediated myofibroblast activation
upregulation of TGFalpha or FGF2 expression is not a pre-requisite for enhanced testicular growth and increased Sertoli cell proliferation that occurs subsequent to hemicastration in the neonatal boar
Continuous passive motion can promote b-FGF expression to enhance type III collagen (zeige COL3A1 Proteine) synthesis at the tendon-bone interface in early stage of tendon-bone repair following acute rupture of supraspinatus tendon in rabbits.
Results uncover a novel Sdc2 (zeige SDC2 Proteine)-Tbx16-Fgf2 pathway that regulates epithelial cell morphogenesis.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
basic fibroblast growth factor bFGF
, fibroblast growth factor 2
, heparin-binding growth factor 2
, basic fibroblast growth factor
, Basic fibroblast growth factor
, Heparin-binding growth factor 2