anti-Human EPH Receptor B6 Antikörper für Western Blotting

Recommended EPH Receptor B6 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
EPH Receptor B6 (EPHB6) Antikörper
  • CEK9
  • EPHB5
  • Cekl
  • Mep
  • HEP
  • EPH receptor B6
  • Eph receptor B6
  • EPHB6
  • Ephb6
Epitop
AA 990-1021, C-Term
24
19
11
10
10
8
8
8
7
7
7
6
4
4
3
3
3
2
1
1
1
1
1
1
1
Reaktivität
Human
172
64
35
4
3
1
1
1
1
Wirt
Kaninchen
104
63
16
6
2
Klonalität
Polyklonal
Konjugat
Dieser EPH Receptor B6 Antikörper ist unkonjugiert
10
9
8
7
6
6
5
5
4
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
140
102
77
48
46
18
13
10
5
3
2
1
1
1
1
1
Optionen
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Produktnummer ABIN391928
$ 324.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.2286417 ABIN2704764 IP WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
3.2286417 ABIN1533496 IF IHC ELISA WB Rabbit IgG AA 861-910 Anmelden zum Anzeigen Polyclonal 1
3.2286417 ABIN391927 FACS IHC (p) WB Rabbit Ig Fraction AA 45-74, N-Term Anmelden zum Anzeigen Polyclonal 2
3.2286417 ABIN359819 EIA IHC (p) WB Rabbit Ig Fraction C-Term Anmelden zum Anzeigen Polyclonal 5
3.2286417 ABIN359818 EIA IHC (p) WB Rabbit Ig Fraction N-Term Anmelden zum Anzeigen Polyclonal 5
3.2286417 ABIN2776160 WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 0
3.2286417 ABIN781859 EIA IHC (p) WB Mouse IgG2a Anmelden zum Anzeigen 5D8 0
3.2286417 ABIN560773 IHC (p) ELISA WB Mouse IgG2a kappa AA 23-122, partial Anmelden zum Anzeigen 5D8 1
3.2286417 ABIN1881301 WB Rabbit AA 503-530, Center Anmelden zum Anzeigen Polyclonal 3
3.2286417 ABIN449957 IHC (fro) IHC (p) IHC ELISA WB Mouse IgG1 Anmelden zum Anzeigen 2A6B9 0
3.2286417 ABIN3184513 ELISA IF IHC WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
3.2286417 ABIN498409 IF IHC (p) WB Rabbit Anmelden zum Anzeigen Polyclonal 0
3.2286417 ABIN969479 IHC ELISA WB Mouse IgG1 Anmelden zum Anzeigen 8E7H12 2
3.2286417 ABIN4308728 WB Rabbit IgG Center Anmelden zum Anzeigen Polyclonal 0
3.2286417 ABIN931461 IHC ELISA WB Mouse IgG1 AA 601-750 Anmelden zum Anzeigen 2A6B9 0
3.2286417 ABIN560771 ELISA WB Mouse IgG2a kappa AA 23-122, partial Anmelden zum Anzeigen 5H6 0
3.2286417 ABIN1107117 EIA IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 2A6B9 4
3.2286417 ABIN4308727 ELISA IHC IHC (fro) IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 8E7H12 0
3.2286417 ABIN2983287 IHC ELISA WB Mouse IgG1 Anmelden zum Anzeigen 0
3.2286417 ABIN1848956 ELISA IF/ICC IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0

General

Antigen EPH Receptor B6 (EPHB6) Antikörper
Epitop AA 990-1021, C-Term
(24), (19), (11), (10), (10), (8), (8), (8), (7), (7), (7), (6), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(172), (64), (35), (4), (3), (1), (1), (1), (1)
Wirt Kaninchen
(104), (63), (16), (6), (2)
Klonalität (Klon)
Polyklonal   ( )
Konjugat Dieser EPH Receptor B6 Antikörper ist unkonjugiert
(10), (9), (8), (7), (6), (6), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(140), (102), (77), (48), (46), (18), (13), (10), (5), (3), (2), (1), (1), (1), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-EPH Receptor B6 Antikörper

Target Details EPH Receptor B6 Anwendungsinformationen Handhabung Referenzen für anti-EPH Receptor B6 Antikörper (ABIN391928) Bilder
Spezifität This EphB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 977~1006 amino acids from C-terminal region with histidine at postion990 of human EphB6.
Reinigung This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This EphB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 990-1021 AA from the C-terminal region of human EphB6.
Klon RB1666
Isotyp Ig Fraction

Target Details EPH Receptor B6

Produktdetails anti-EPH Receptor B6 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-EPH Receptor B6 Antikörper (ABIN391928) Bilder zurück nach oben
Antigen
Andere Bezeichnung EphB6 (EPHB6 Antibody Abstract)
Hintergrund Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB6 lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.
Synonyms: Ephrin type-B receptor 6, Tyrosine-protein kinase-defective receptor EPH-6, HEP
Molekulargewicht 109272 DA
Gen-ID 2051
UniProt O15197
Pathways RTK Signalweg, Hormone Transport

Anwendungsinformationen

Produktdetails anti-EPH Receptor B6 Antikörper Target Details EPH Receptor B6 Handhabung Referenzen für anti-EPH Receptor B6 Antikörper (ABIN391928) Bilder zurück nach oben
Applikationshinweise WB = 1:1000, IHC (p) = 1:50-100
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-EPH Receptor B6 Antikörper Target Details EPH Receptor B6 Anwendungsinformationen Referenzen für anti-EPH Receptor B6 Antikörper (ABIN391928) Bilder zurück nach oben
Format Liquid
Konzentration 1.11 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit 6 months

Referenzen für anti-EPH Receptor B6 Antikörper (ABIN391928)

Produktdetails anti-EPH Receptor B6 Antikörper Target Details EPH Receptor B6 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Gu, Li, Qian, Chen, Wang, Wang: "Expression of EphB6 in ovarian serous carcinoma is associated with grade, TNM stage and survival." in: Journal of clinical pathology, 2015

Brantley-Sieders, Jiang, Sarma, Badu-Nkansah, Walter, Shyr, Chen: "Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome." in: PLoS ONE, Vol. 6, Issue 9, pp. e24426, 2011

Yu, Bulk, Ji, Hascher, Tang, Metzger, Marra, Serve, Berdel, Wiewroth, Koschmieder, Müller-Tidow: "The EPHB6 receptor tyrosine kinase is a metastasis suppressor that is frequently silenced by promoter DNA hypermethylation in non-small cell lung cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 8, pp. 2275-83, 2010

Allgemeine Veröffentlichungen

Freywald, Sharfe, Rashotte, Grunberger, Roifman: "The EphB6 receptor inhibits JNK activation in T lymphocytes and modulates T cell receptor-mediated responses." in: The Journal of biological chemistry, Vol. 278, Issue 12, pp. 10150-6, 2003

Tang, Zhao, Robinson, Cohen, Cnaan, London, Cohn, Cheung, Brodeur, Evans, Ikegaki: "Implications of EPHB6, EFNB2, and EFNB3 expressions in human neuroblastoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 20, pp. 10936-41, 2000

Bilder

Produktdetails anti-EPH Receptor B6 Antikörper Target Details EPH Receptor B6 Anwendungsinformationen Handhabung Referenzen für anti-EPH Receptor B6 Antikörper (ABIN391928) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-EPH Receptor B6 (EPHB6) (AA 990-1021), (C-Term) antibody (ABIN391928) Western blot analysis of anti-EphB6 C-term Pab (ABIN391928) in Jurkat cell lysate. Ep...
Immunohistochemistry (IHC) image for anti-EPH Receptor B6 (EPHB6) (AA 990-1021), (C-Term) antibody (ABIN391928) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...