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SGLT2 (zeige SLC5A2 ELISA Kits)/MAP17 functions as a low-affinity Na(+)-glucose cotransporter (zeige SLC5A1 ELISA Kits) in the kidney.
Differential gene expression analysis demonstrated significant upregulation of PDZK1IP1, EEF1A2 (zeige EEF1A2 ELISA Kits) and RPL41 (zeige RPL41 ELISA Kits) (ENSG00000279483) genes in the intrahepatic cholangiocarcinoma samples when compared with the matched paratumor samples.
Data show that bortezomib induces a prosurvival response through cytoprotective autophagy and nuclear factor kappa B (NFkappaB (zeige NFKB1 ELISA Kits)) nuclear translocation, which is repressed by high levels of membrane-associated protein 17 (MAP17).
In this study we found that the levels of MAP17 were related to clinical findings and survival in a cohort of 58 patients with larynx cancer
Results suggest that the use of MAP17 and SGLT1 (zeige SLC5A1 ELISA Kits) markers may identify patients who are likely to exhibit a better response to treatments that boost oxidative stress in other cancer types.
MAP17 is overexpressed in late-stage breast tumors, in which oncogenic activity relies on p38 (zeige CRK ELISA Kits) insensitivity to induce intracellular ROS (zeige ROS1 ELISA Kits).
The Th cell cytokine-induced up-regulation of MAP17 expression may be linked to the down-regulation of filaggrin (zeige FLG ELISA Kits) in normal epidermal keratinocytes, which may be associated with abnormal epidermal differentiation observed in the dermatological diseases.
Large scale genetic screening identifies MAP17 as protein bypassing TNF-alpha (zeige TNF ELISA Kits)-induced growth arrest.
Independent activation of MAP17 promoter can be driven by oncogenes and might explain the common overexpression of MAP17 in human carcinomas.
Tumorigenic capability of MAP17 through a connection between sodium-coupled co-transporters and reactive oxygen species.
membrane associated protein 17 may be an endogenous regulator of cellular PDZ domain containing 1(PDZK1 (zeige PDZK1 ELISA Kits)) levels by regulating PDZK1 (zeige PDZK1 ELISA Kits) turnover
MAP17 1) interacts with PDZK1 (zeige PDZK1 ELISA Kits) only, 2) associates with the NH2 terminus of NaPi-IIa within the PDZK1 (zeige PDZK1 ELISA Kits)/NaPi-IIa/MAP17 complex, and 3) acts as an apical anchoring site for PDZK1 (zeige PDZK1 ELISA Kits).
the interaction between MAP17, NHERF3 (zeige PDZK1 ELISA Kits)/4, and NaPiIIa in the trans-Golgi network could be an important intermediate or alternate path in the internalization of NaPiIIa
Knockout mice for 3 members of the sodium-hydrogen regulatory factor (NHERF (zeige SLC9A3R1 ELISA Kits)) family of PDZ (zeige INADL ELISA Kits) adaptor proteins, NHERF1 (EBP50 (zeige SLC9A3R1 ELISA Kits)), NHERF2 (E3KARP (zeige SLC9A3R2 ELISA Kits)) and NHERF3 (PDZK1 (zeige PDZK1 ELISA Kits)), have helped to show that NHERF1 (zeige SLC9A3R2 ELISA Kits) is essential for both normal and mutant CFTR (zeige CFTR ELISA Kits) function [review]
Systematic analysis of Pdzk1ip1 is reported.
XPteg functions as a direct transcriptional target of RA signaling to regulate pronephric tubulogenesis in Xenopus early development
expressed specifically in kidney\; increased expression is detected in renal carcinoma
PDZK1-interacting protein 1
, 17 kDa membrane-associated protein
, PDZK1 interacting protein 1
, epithelial protein up-regulated in carcinoma, membrane associated protein 17
, membrane-associated protein 17
, membrane-associated protein 17 (Map17)
, MAP-like protein
, MAP17-like protein
, membrane-associated protein
, proximal tubules-expressed gene protein
, proximal tubules-expressing