anti-Human CRY1 Antikörper für Western Blotting

Recommended CRY1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Cryptochrome 1 (Photolyase-Like) (CRY1) Antikörper
  • cry1-A
  • CRY1
  • cry2
  • phll1
  • xCRY1
  • PHLL1
  • AU020726
  • AU021000
  • Phll1
  • ATCRY1
  • BLU1
  • BLUE LIGHT UNINHIBITED 1
  • CRYPTOCHROME 1 APOPROTEIN (BLUE LIGHT PHOTORECEPTOR
  • ELONGATED HYPOCOTYL 4
  • HY4
  • OOP2
  • OUT OF PHASE 2
  • T3H13.14
  • T3H13_14
  • cryptochrome 1
  • cryptochrome circadian clock 1 L homeolog
  • cryptochrome circadian regulator 1
  • cryptochrome circadian clock 1
  • Cryptochrome-1
  • cryptochrome 1
  • cryptochrome 1 (photolyase-like)
  • cry1.L
  • CRY1
  • cry1
  • siu50817b
  • Cry1
Epitop
AA 556-586, C-Term
25
6
6
4
3
3
3
3
2
1
1
1
1
Reaktivität
Human
64
18
9
4
3
2
2
2
2
2
1
1
1
1
Wirt
Kaninchen
49
21
3
Klonalität
Polyklonal
Konjugat
Dieser CRY1 Antikörper ist unkonjugiert
2
2
2
2
2
2
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
68
38
35
16
11
6
3
2
2
2
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN390079
$ 324.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.3284883 ABIN3042761 WB Rabbit IgG AA 153-189, N-Term Anmelden zum Anzeigen Polyclonal
3.3284883 ABIN2788200 IHC WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 1
3.3284883 ABIN781975 EIA IF IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 4H4-1C4
3.3284883 ABIN4892971 IHC IHC (p) SimWes WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal
3.3284883 ABIN396476 WB Mouse IgG1 kappa AA 1-587 Anmelden zum Anzeigen 4H4-1C4
3.3284883 ABIN3197614 IHC WB Rabbit Anmelden zum Anzeigen Polyclonal
3.3284883 ABIN2562023 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
3.3284883 ABIN560474 IF IHC (p) ELISA WB Mouse IgG1 kappa AA 1-586, full length Anmelden zum Anzeigen 4H4-1C4
3.3284883 ABIN514616 IF WB Mouse AA 1-586, full length Anmelden zum Anzeigen Polyclonal
3.3284883 ABIN1867398 ICC IHC IP WB Rabbit IgG AA 3-132 Anmelden zum Anzeigen Polyclonal
1 ABIN358613 EIA IHC (p) WB Rabbit Ig Fraction C-Term Anmelden zum Anzeigen Polyclonal 5
1 ABIN958965 IHC (p) WB Rabbit AA 151-200 Anmelden zum Anzeigen Polyclonal
1 ABIN626034 IF IHC (p) ELISA WB Mouse IgG1, kappa AA 1-587 Anmelden zum Anzeigen 4H4-1C4
1 ABIN294034 IHC ELISA WB Goat IgG AA 115-224 Anmelden zum Anzeigen Polyclonal
1 ABIN603032 WB Mouse IgG1 C-Term Anmelden zum Anzeigen
1 ABIN201975 IHC ELISA WB Rabbit AA 571-586 Anmelden zum Anzeigen Polyclonal
1 ABIN1964706 IHC ELISA WB APC Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN1962327 IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN1968827 IHC ELISA WB Biotin Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN1971131 IHC ELISA WB FITC Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal

General

Antigen Cryptochrome 1 (Photolyase-Like) (CRY1) Antikörper
Epitop AA 556-586, C-Term
(25), (6), (6), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1)
Reaktivität Human
(64), (18), (9), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(49), (21), (3)
Klonalität (Klon)
Polyklonal   ( )
Konjugat Dieser CRY1 Antikörper ist unkonjugiert
(2), (2), (2), (2), (2), (2)
Applikation Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(68), (38), (35), (16), (11), (6), (3), (2), (2), (2), (1), (1)
Pubmed 4 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CRY1 Antikörper

Target Details CRY1 Anwendungsinformationen Handhabung Referenzen für anti-CRY1 Antikörper (ABIN390079) Bilder
Spezifität This Cry1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557~586 amino acids from the C-terminal region of human Cry1.
Homologie Monkey
Reinigung This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This Cry1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 556-586 AA from the C-terminal region of human Cry1.
Klon RB1844
Isotyp Ig Fraction

Target Details CRY1

Produktdetails anti-CRY1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CRY1 Antikörper (ABIN390079) Bilder zurück nach oben
Antigen
Andere Bezeichnung Cry1 (CRY1 Antibody Abstract)
Hintergrund Various biochemical, physiological and behavioural processes display circadian rhythms controlled by an internal biological clock. The central モgears?driving this clock appear to be composed of an autoregulatory transcription/posttranslation-based feedback loop. Cryptochrome 1 (CRY1) and 2 (CRY2) are DNA-binding flavoproteins that bear some homology to blue-light receptors and photolyases. In Drosophila, CRY is a photoreceptor for the circadian clock where it binds to the clock component TIM in a light-dependent fashion and blocks its function. Mammalian CRY1 and CRY2 function via light-independent interactions with circadian genes CLOCK and BMAL1, as well as with PER1, PER2, and TIM. They seem to act as light-independent components of the circadian clock and likely regulate Per1 transcriptional cycling via interactions with both the activator and its feedback inhibitors. Mutant mice not expressing the Cry1 or Cry2 protein display accelerated and delayed periodicity of locomotor activity, respectively. It appears that the combination of both proteins working together is essential to synchronize the organism to circadian phases. A critical balance between Cry1 and Cry2 is required for proper clock function, in complete darkness, double-mutant mice present with instantaneous arrhythmicity, indicating the absence of an internal circadian clock.
Synonyms: Cryptochrome-1, PHLL1
Molekulargewicht 66394 DA
Gen-ID 1407
UniProt Q16526
Forschungsgebiet Translation Factors, Cell Cycle, Transcription Factors, Signaling, Cell Structure
Pathways Response to Water Deprivation, Proton Transport

Anwendungsinformationen

Produktdetails anti-CRY1 Antikörper Target Details CRY1 Handhabung Referenzen für anti-CRY1 Antikörper (ABIN390079) Bilder zurück nach oben
Applikationshinweise WB = 1:1000, IHC (p) = 1:50-100
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CRY1 Antikörper Target Details CRY1 Anwendungsinformationen Referenzen für anti-CRY1 Antikörper (ABIN390079) Bilder zurück nach oben
Format Liquid
Konzentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit 6 months

Referenzen für anti-CRY1 Antikörper (ABIN390079)

Produktdetails anti-CRY1 Antikörper Target Details CRY1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Griffin, Staknis, Weitz: "Light-independent role of CRY1 and CRY2 in the mammalian circadian clock." in: Science (New York, N.Y.), Vol. 286, Issue 5440, pp. 768-71, 1999

van der Horst, Muijtjens, Kobayashi, Takano, Kanno, Takao, de Wit, Verkerk, Eker, van Leenen, Buijs, Bootsma, Hoeijmakers, Yasui: "Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms." in: Nature, Vol. 398, Issue 6728, pp. 627-30, 1999

Kobayashi, Kanno, Smit, van der Horst, Takao, Yasui: "Characterization of photolyase/blue-light receptor homologs in mouse and human cells." in: Nucleic acids research, Vol. 26, Issue 22, pp. 5086-92, 1999

Hsu, Zhao, Zhao, Kazantsev, Wang, Todo, Wei, Sancar: "Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins." in: Biochemistry, Vol. 35, Issue 44, pp. 13871-7, 1996

Bilder

Produktdetails anti-CRY1 Antikörper Target Details CRY1 Anwendungsinformationen Handhabung Referenzen für anti-CRY1 Antikörper (ABIN390079) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 556-586), (C-Term) antibody (ABIN390079) The anti-Cry1 N-term Pab (ABIN390079) is used in Western blot to detect Cry1 in place...
Immunohistochemistry (IHC) image for anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 556-586), (C-Term) antibody (ABIN390079) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...