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anti-Human TACR1 Antikörper:
anti-Mouse (Murine) TACR1 Antikörper:
anti-Rat (Rattus) TACR1 Antikörper:
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Human Polyclonal TACR1 Primary Antibody für ICC, FACS - ABIN152468
Lai, Ho, Kilpatrick, Wang, Tuluc, Korchak, Douglas: Full-length and truncated neurokinin-1 receptor expression and function during monocyte/macrophage differentiation. in Proceedings of the National Academy of Sciences of the United States of America 2006
Show all 36 Pubmed References
Guinea Pig Polyclonal TACR1 Primary Antibody für ICC, IHC (fro) - ABIN152451
Anderson, Seybold: Phosphorylated cAMP response element binding protein increases in neurokinin-1 receptor-immunoreactive neurons in rat spinal cord in response to formalin-induced nociception. in Neuroscience letters 2000
Show all 30 Pubmed References
Human Polyclonal TACR1 Primary Antibody für ICC, IF - ABIN261566
Cavanaugh, Lee, Lo, Shields, Zylka, Basbaum, Anderson: Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli. in Proceedings of the National Academy of Sciences of the United States of America 2009
Human Polyclonal TACR1 Primary Antibody für ELISA, WB - ABIN563081
Chernova, Lai, Li, Schwartz, Tuluc, Korchak, Douglas, Kilpatrick: Substance P (SP) enhances CCL5-induced chemotaxis and intracellular signaling in human monocytes, which express the truncated neurokinin-1 receptor (NK1R). in Journal of leukocyte biology 2008
Cow (Bovine) Polyclonal TACR1 Primary Antibody für IHC (p) - ABIN4339804
Chui, Di Girolamo, Coroneo, Wakefield: The role of substance P in the pathogenesis of pterygia. in Investigative ophthalmology & visual science 2007
Human Polyclonal TACR1 Primary Antibody für FACS, ICC - ABIN4235052
Altawil, Lyström, El-Nour: Kinetics of neuronal contribution during the development of a contact allergic reaction. in Archives of dermatological research 2012
Human Monoclonal TACR1 Primary Antibody für FACS - ABIN4898761
Taracanova, Alevizos, Karagkouni, Weng, Norwitz, Conti, Leeman, Theoharides: SP and IL-33 together markedly enhance TNF synthesis and secretion from human mast cells mediated by the interaction of their receptors. in Proceedings of the National Academy of Sciences of the United States of America 2017
Expression of NK1R increases in the eosinophils of chronic spontaneous urticaria (CSU) patients. Blockers of NK1R might be used for CSU treatment.
NK-1R may positively regulate melanogenesis through Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling pathway.
This study revealed for the first time an increase of Mast Cells -nerve association and NK1R expression on Mast Cells during Allergic Rhinitis as well as nerve fibres containing receptors for mass cells.
Kinase activation led to increased MMP-2 (zeige MMP2 Antikörper) and MT1-MMP (zeige MMP14 Antikörper) expression and melanoma cell migration induced by hHK-1 (zeige HOOK1 Antikörper). Thus, hHK-1 (zeige HOOK1 Antikörper) and the NK1 receptor are critical to melanoma cell migration and each may be a promising chemotherapeutic target
Within a small cohort of patients who presented for treatment,a novel gene was identified that appears to contribute to anorexia nervosa pathophysiology, TACR1.
NK1 receptor expression is increased in colonic tissues from experimental colitis models and in the colon of Irritable Bowel Disease patients.
High Truncated Neurokinin-1 Receptor expression is associated with Neuroblastoma (zeige ARHGEF16 Antikörper).
Abnormalities in substance P neurokinin-1 (zeige TAC1 Antikörper) receptor binding in key brainstem nuclei is associated with sudden infant death syndrome.
TGF-beta1 (zeige TGFB1 Antikörper) down-regulates the gene expression of the full-length variant of NK-1 (zeige CD160 Antikörper) R in human keratocytes, which might impact its signaling pathway and thus explain the known delay in internalization after activation by SP seen with TGF-beta1 (zeige TGFB1 Antikörper) treatment.
Expression substance P/neurokinin A (zeige TAC1 Antikörper)/hemokinin-1 and their preferred neurokinin 1/neurokinin 2 (zeige TAC1 Antikörper) receptors are dysregulated in uterine leiomyomata.
results indicate the contribution of NK1R signaling in maintaining the homeostasis of the ocular surface under steady-state condition, and that the lack of functional NK1R increases the susceptibility of eyes to develop severe herpes stromal keratitis upon ocular HSV-1 infection
the NK1R-CreER mouse line is a valuable new tool for conditional gene manipulation enabling the visualization and manipulation of cells that express NK1R.
NK1R-/- mice did not exhibit excessive false alarms, compared with wildtypes (response disinhibition) but, as in the 5-Choice ContinuousPerformance Test, they exhibited more perseverative responses throughout the test
NK1R-expressing dorsal horn neurons play a major role in the expression of symptoms of chronic itch.
The results of this study indicated that certain behaviours, disrupted in ADHD, are influenced by an interaction between the BRAS and NK1R, and suggest that ACE (zeige ACE Antikörper) inhibitors could provide a novel treatment for this disorder.
Results provide evidence linking enhanced waking activity and the pro-inflammatory molecule substance P (zeige TAC1 Antikörper) to changes in slow-wave activity associated with sleep-active cortical cells that co-express nNOS (zeige NOS1 Antikörper) and the NK-1R
the hyperactivity, perseveration and, possibly, inattentiveness of NK1R-/- mice is a direct consequence of a lack of functional NK1R
Substance P (zeige TAC1 Antikörper) partly accounts for the increased density of microglia in the substantia nigra through chemotaxic recruitment via a novel NK1R-NOX2 (zeige CYBB Antikörper) axis-mediated pathway.
NK1 (zeige HGF Antikörper)-R expression in the trachea, bronchus, and lung tissue increased in MP-infected BALB/c mice, which may explain why wheezing occurs after MP infection.
The behavioural response of mice lacking NK1r to guanfacine resembles its clinical profile in treatment of ADHD
Implanting vascular bundles into the tissue engineered bone can significantly improve the expression levels of NK1R and VIPR1 (zeige VIPR1 Antikörper).
Activation of neurokinin-1 (zeige TAC1 Antikörper) receptors in primary sensory neurons plays a role in the generation of overactive bladder.
Substance P (zeige TAC1 Antikörper) and SP-R mRNA expressions were reduced after IMETIT treatment of allergic rhinitis.
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P.
, substance-P receptor
, tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor)
, Nk1 receptor
, neurokinin receptor 1
, substance P receptor
, neurokinin 1 receptor
, substance p receptor
, neurokinin receptor subtype NK1
, tachikinin receptor 1
, tachykinin receptor 1
, neurokinin-1 receptor