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Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validierenRelevance Score | ABIN | Application | Konjugat | Host | Isotype | Epitope | Hersteller | Clonality | References | Details |
---|---|---|---|---|---|---|---|---|---|---|
1 | ABIN1701008 | IHC (p) | Biotin | Rabbit | IgG | Anmelden zum Anzeigen | Polyclonal | 0 | ||
1 | ABIN1714510 | IF (p) IHC (p) | Rabbit | IgG | Anmelden zum Anzeigen | Polyclonal | 0 |
General |
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Antigen | Cell Adhesion Molecule-Related/down-Regulated By Oncogenes (CDON) Antikörper |
Reaktivität | Human, Maus, Ratte (Rattus) Alternativen |
Wirt | Kaninchen Alternativen |
Klonalität | |
Konjugat | HRP Alternativen |
Applikation |
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Alternativen
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Hersteller | Anmelden zum Anzeigen |
ProduktdetailsAntigendetails Anwendungsinformationen Handhabung Bilder |
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Reinigung | Purified by Protein A. |
Immunogen | KLH conjugated synthetic peptide derived from human CDON |
Isotyp | IgG |
AntigendetailsProduktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben |
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Antigen | |
Andere Bezeichnung | Cdon (CDON Antibody Abstract) |
Hintergrund |
Cell adhesion molecule-related/down-regulated by oncogenes (CDO) and BOC (brother of CDO) are members of the immunoglobulin/fibronectin type III repeat family and act as cell surface receptors. CDO is a component of a cell-surface receptor complex which also contains BOC, NEO1, CTNNB1 and cadherins and which acts as a mediator of cell-cell interactions between muscle cells. CDO and BOC are single pass membrane proteins that play a role in myogenic cell differentiation. Together, CDO and BOC participate in a positive feedback loop with MyoD, a myogenic transcription factor. The 1,242 amino acid rat CDO protein has a 24 residue signal sequence, five Ig V-like repeats, a 25 residue membrane-spanning region, three FNIII-like repeats and a cytoplasmic region of 256 amino acids containing a proline-rich stretch. The human protein contains 1,225 amino acid residues and shares significant homology with the domain structures of the rat protein. Subcellular location: Extracellular Synonyms: CDO, CDON, Cell adhesion molecule-related/down-regulated by oncogenes, CDON_HUMAN. |
Gen-ID | 50937 |
Pathways | Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Embryonic Body Morphogenesis |
AnwendungsinformationenProduktdetails Antigendetails Handhabung Bilder zurück nach oben |
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Applikationshinweise | IHC-P 1:100-500 |
Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben |
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Format | Liquid |
Konzentration | 1 μg/μL |
Buffer | Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin. |
Konservierungsmittel | Gentamicin sulfate |
Vorsichtsmaßnahmen | This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handhabung | Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase. |
Lagerung | 4 °C |
Informationen zur Lagerung | Store at 4°C |
Haltbarkeit | 12 months |